3D Electron Microscopy (3D-EM) Data Navigator [English / [日本語]]
Top Gallery List Statistics Shape search Viewer
Movie pageYodrodumi (structure viewer)
PDBj>EM Navigator>Detail page - PDB-5xti

This page is a legacy version and will be discarded in future. The new page is here.

Cryo-EM architecture of human respiratory chain megacomplex-I2III2IV2

by single particle reconstruction, at 17.4 A resolution

Movie

Orientation:

#1: Deposited structure unit, Imaged by Jmol

#2: Superimposition on EM map, EMDB-6776, Imaged by UCSF CHIMERA

Entry
Summary
Database / IDPORTEIN DATA BANK (PDB) / 5xti
TitleCryo-EM architecture of human respiratory chain megacomplex-I2III2IV2
DescriptorAcyl carrier protein,mitochondrial
NADH-ubiquinone oxidoreductase 75 kDa subunit,mitochondrial
heme protein,mitochondrial
(NADH dehydrogenase [ubiquinone] flavoprotein ...) x 3
(NADH dehydrogenase [ubiquinone] iron-sulfur protein ...) x 7
and more 5 items
KeywordsOXIDOREDUCTASE/ELECTRON TRANSPORT, Homo sapiens, Oxidoreductase, Respiratory, OXIDOREDUCTASE-ELECTRON TRANSPORT complex
AuthorsGu, J., Wu, M., Yang, M.
DateDeposition: 2017-06-19, Release: 2017-09-13
PDBj Mine pagesSummary, Structural Details, Experimental Details, Functional Details
Other databasesRCSB-PDB, PDBe, FSSP, SCOP
Structure Visualization
MoviesMovie Page

#1: Deposited structure unit, Imaged by Jmol

#2: Superimposition on EM map, EMDB-6776, Imaged by UCSF CHIMERA

Structure viewersYorodumi, jV4, Jmol, Biological unit (Images, jV)
Related Structure Data
Related Entries

EMDB-6776

CiteFit

Cite: data citing same article

Fit: target map of fitting

Similar-shape strucutres
Search for similar-shape assemblies throgh:
EMDB + EM entries in PDB
all of EMDB & PDB (Omokage search)
Article
Citation - primary
ArticleCell, Vol. 170, Issue 6, Page 1247-1257.e12, Year 2017
TitleArchitecture of Human Mitochondrial Respiratory Megacomplex I2III2IV2.
AuthorsRunyu Guo, Shuai Zong, Meng Wu, Jinke Gu, Maojun Yang
Ministry of Education Key Laboratory of Protein Science, Tsinghua-Peking Joint Center for Life Sciences, Beijing Advanced Innovation Center for Structural Biology, School of Life Sciences, Tsinghua University, 100084 Beijing, China.
LinksPubMed: 28844695, PII: S0092-8674(17)30887-5, DOI: 10.1016/j.cell.2017.07.050
Components
ID 1 : Complex I-51kD,CI-51kD,NADH dehydrogenase flavoprotein 1,NADH-ubiquinone oxidoreductase 51 kDa subunit
DescriptionNADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial
Typepolypeptide(L)
FragmentUNP RESIDUES 27-457
Formula weight47323.938 Da
Number of molecules2
ID1
Ec1.6.5.3,1.6.99.3
SourceMethod: Isolated from a natural source
Src id: 1
Common name: Human
Alt source flag: sample
Beg seq num: 1
End seq num: 431
NCBI taxonomy: ID:9606
Organism scientific: Homo sapiens
LinksUniProt: P49821, Sequence view
ID 2 : Complex I-23kD,CI-23kD,NADH-ubiquinone oxidoreductase 23 kDa subunit,TYKY subunit
DescriptionNADH dehydrogenase [ubiquinone] iron-sulfur protein 8, mitochondrial
Typepolypeptide(L)
Formula weight20314.037 Da
Number of molecules2
ID2
Ec1.6.5.3,1.6.99.3
SourceMethod: Isolated from a natural source
Src id: 1
Common name: Human
Alt source flag: sample
Beg seq num: 1
End seq num: 176
NCBI taxonomy: ID:9606
Organism scientific: Homo sapiens
LinksUniProt: O00217, Sequence view
ID 3 : Complex I-20kD,CI-20kD,NADH-ubiquinone oxidoreductase 20 kDa subunit,PSST subunit
DescriptionNADH dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial
Typepolypeptide(L)
FragmentUNP RESIDUES 58-213
Formula weight17887.928 Da
Number of molecules2
ID3
Ec1.6.5.3,1.6.99.3
SourceMethod: Isolated from a natural source
Src id: 1
Common name: Human
Alt source flag: sample
Beg seq num: 1
End seq num: 156
NCBI taxonomy: ID:9606
Organism scientific: Homo sapiens
LinksUniProt: O75251, Sequence view
ID 4 : Complex I-B14,CI-B14,LYR motif-containing protein 6,NADH-ubiquinone oxidoreductase B14 subunit
DescriptionNADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 6
Typepolypeptide(L)
FragmentUNP RESIDUES 42-154
Formula weight13758.070 Da
Number of molecules2
ID4
SourceMethod: Isolated from a natural source
Src id: 1
Common name: Human
Alt source flag: sample
Beg seq num: 1
End seq num: 113
NCBI taxonomy: ID:9606
Organism scientific: Homo sapiens
LinksUniProt: P56556, Sequence view
ID 5 : Complex I-B8,CI-B8,NADH-ubiquinone oxidoreductase B8 subunit
DescriptionNADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2
Typepolypeptide(L)
FragmentUNP RESIDUES 14-96
Formula weight9535.905 Da
Number of molecules2
ID5
SourceMethod: Isolated from a natural source
Src id: 1
Common name: Human
Alt source flag: sample
Beg seq num: 1
End seq num: 83
NCBI taxonomy: ID:9606
Organism scientific: Homo sapiens
LinksUniProt: O43678, Sequence view
ID 6 : ACP,CI-SDAP,NADH-ubiquinone oxidoreductase 9.6 kDa subunit
DescriptionAcyl carrier protein, mitochondrial
Typepolypeptide(L)
FragmentUNP RESIDUES 72-196
Formula weight9845.247 Da
Number of molecules4
ID6
SourceMethod: Isolated from a natural source
Src id: 1
Common name: Human
Alt source flag: sample
Beg seq num: 1
End seq num: 85
NCBI taxonomy: ID:9606
Organism scientific: Homo sapiens
LinksUniProt: O14561, Sequence view
ID 7 : Complex I subunit B13,Complex I-13kD-B,CI-13kD-B,NADH-ubiquinone oxidoreductase 13 kDa-B subunit
DescriptionNADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 5
Typepolypeptide(L)
FragmentUNP RESIDUES 5-116
Formula weight13119.208 Da
Number of molecules2
ID7
SourceMethod: Isolated from a natural source
Src id: 1
Common name: Human
Alt source flag: sample
Beg seq num: 1
End seq num: 112
NCBI taxonomy: ID:9606
Organism scientific: Homo sapiens
LinksUniProt: Q16718, Sequence view
ID 8 : Complex I-B14.5a,CI-B14.5a,NADH-ubiquinone oxidoreductase subunit B14.5a
DescriptionNADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 7
Typepolypeptide(L)
FragmentUNP RESIDUES 4-113
Formula weight12282.051 Da
Number of molecules2
ID8
SourceMethod: Isolated from a natural source
Src id: 1
Common name: Human
Alt source flag: sample
Beg seq num: 1
End seq num: 110
NCBI taxonomy: ID:9606
Organism scientific: Homo sapiens
LinksUniProt: O95182, Sequence view
ID 9 : Complex I-39kD,CI-39kD,NADH-ubiquinone oxidoreductase 39 kDa subunit
DescriptionNADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 9, mitochondrial
Typepolypeptide(L)
FragmentUNP RESIDUES 40-376
Formula weight38387.594 Da
Number of molecules2
ID9
SourceMethod: Isolated from a natural source
Src id: 1
Common name: Human
Alt source flag: sample
Beg seq num: 1
End seq num: 337
NCBI taxonomy: ID:9606
Organism scientific: Homo sapiens
LinksUniProt: Q16795, Sequence view
ID 10 : Complex I-9kD,CI-9kD,NADH-ubiquinone oxidoreductase 9 kDa subunit,Renal carcinoma antigen NY-REN-4
DescriptionNADH dehydrogenase [ubiquinone] flavoprotein 3, mitochondrial
Typepolypeptide(L)
FragmentUNP RESIDUES 74-106
Formula weight3900.312 Da
Number of molecules2
ID10
SourceMethod: Isolated from a natural source
Src id: 1
Common name: Human
Alt source flag: sample
Beg seq num: 1
End seq num: 33
NCBI taxonomy: ID:9606
Organism scientific: Homo sapiens
LinksUniProt: P56181, Sequence view
ID 11 : Complex I-18 kDa,CI-18 kDa,Complex I-AQDQ,CI-AQDQ,NADH-ubiquinone oxidoreductase 18 kDa subunit
DescriptionNADH dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial
Typepolypeptide(L)
FragmentUNP RESIDUES 58-175
Formula weight13721.598 Da
Number of molecules2
ID11
SourceMethod: Isolated from a natural source
Src id: 1
Common name: Human
Alt source flag: sample
Beg seq num: 1
End seq num: 118
NCBI taxonomy: ID:9606
Organism scientific: Homo sapiens
LinksUniProt: O43181, Sequence view
ID 12 : Complex I-75kD,CI-75kD
DescriptionNADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial
Typepolypeptide(L)
FragmentUNP RESIDUES 30-716
Formula weight75471.484 Da
Number of molecules2
ID12
Ec1.6.5.3,1.6.99.3
SourceMethod: Isolated from a natural source
Src id: 1
Common name: Human
Alt source flag: sample
Beg seq num: 1
End seq num: 687
NCBI taxonomy: ID:9606
Organism scientific: Homo sapiens
LinksUniProt: P28331, Sequence view
ID 13 : 13 kDa differentiation-associated protein,Complex I-B17.2,CIB17.2,NADH-ubiquinone oxidoreductase subunit B17.2
DescriptionNADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12
Typepolypeptide(L)
FragmentUNP RESIDUES 2-144
Formula weight16880.068 Da
Number of molecules2
ID13
SourceMethod: Isolated from a natural source
Src id: 1
Common name: Human
Alt source flag: sample
Beg seq num: 1
End seq num: 143
NCBI taxonomy: ID:9606
Organism scientific: Homo sapiens
LinksUniProt: Q9UI09, Sequence view
ID 14 : NADH-ubiquinone oxidoreductase 24 kDa subunit
DescriptionNADH dehydrogenase [ubiquinone] flavoprotein 2, mitochondrial
Typepolypeptide(L)
FragmentUNP RESIDUES 36-247
Formula weight23430.881 Da
Number of molecules2
ID14
Ec1.6.5.3,1.6.99.3
SourceMethod: Isolated from a natural source
Src id: 1
Common name: Human
Alt source flag: sample
Beg seq num: 1
End seq num: 212
NCBI taxonomy: ID:9606
Organism scientific: Homo sapiens
LinksUniProt: P19404, Sequence view
ID 15 : Complex I-30kD,CI-30kD,NADH-ubiquinone oxidoreductase 30 kDa subunit
DescriptionNADH dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial
Typepolypeptide(L)
FragmentUNP RESIDUES 43-250
Formula weight24432.656 Da
Number of molecules2
ID15
Ec1.6.5.3,1.6.99.3
SourceMethod: Isolated from a natural source
Src id: 1
Common name: Human
Alt source flag: sample
Beg seq num: 1
End seq num: 208
NCBI taxonomy: ID:9606
Organism scientific: Homo sapiens
LinksUniProt: O75489, Sequence view
ID 16 : Complex I-49kD,CI-49kD,NADH-ubiquinone oxidoreductase 49 kDa subunit
DescriptionNADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial
Typepolypeptide(L)
Formula weight49236.480 Da
Number of molecules2
ID16
Ec1.6.5.3,1.6.99.3
SourceMethod: Isolated from a natural source
Src id: 1
Common name: Human
Alt source flag: sample
Beg seq num: 1
End seq num: 430
NCBI taxonomy: ID:9606
Organism scientific: Homo sapiens
LinksUniProt: O75306, Sequence view
ID 17 : Complex I-MWFE,CI-MWFE,NADH-ubiquinone oxidoreductase MWFE subunit
DescriptionNADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 1
Typepolypeptide(L)
Formula weight8084.391 Da
Number of molecules2
ID17
SourceMethod: Isolated from a natural source
Src id: 1
Common name: Human
Alt source flag: sample
Beg seq num: 1
End seq num: 70
NCBI taxonomy: ID:9606
Organism scientific: Homo sapiens
LinksUniProt: O15239, Sequence view
ID 18 : Complex I-13kD-A,CI-13kD-A,NADH-ubiquinone oxidoreductase 13 kDa-A subunit
DescriptionNADH dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrial
Typepolypeptide(L)
FragmentUNP RESIDUES 29-123
Formula weight10578.848 Da
Number of molecules2
ID18
SourceMethod: Isolated from a natural source
Src id: 1
Common name: Human
Alt source flag: sample
Beg seq num: 1
End seq num: 95
NCBI taxonomy: ID:9606
Organism scientific: Homo sapiens
LinksUniProt: O75380, Sequence view
ID 19 : Complex I-B9,CI-B9,NADH-ubiquinone oxidoreductase B9 subunit
DescriptionNADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 3
Typepolypeptide(L)
Formula weight9156.602 Da
Number of molecules2
ID19
SourceMethod: Isolated from a natural source
Src id: 1
Common name: Human
Alt source flag: sample
Beg seq num: 1
End seq num: 83
NCBI taxonomy: ID:9606
Organism scientific: Homo sapiens
LinksUniProt: O95167, Sequence view
ID 20 : Complex I-B14.7,CI-B14.7,NADH-ubiquinone oxidoreductase subunit B14.7
DescriptionNADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 11
Typepolypeptide(L)
Formula weight14736.853 Da
Number of molecules2
ID20
SourceMethod: Isolated from a natural source
Src id: 1
Common name: Human
Alt source flag: sample
Beg seq num: 1
End seq num: 140
NCBI taxonomy: ID:9606
Organism scientific: Homo sapiens
LinksUniProt: Q86Y39, Sequence view
ID 21 : Cell death regulatory protein GRIM-19,Complex I-B16.6,CI-B16.6,Gene associated with retinoic and interferon-induced mortality 19 protein,Gene associated with retinoic and IFN-induced mortality 19 protein,NADH-ubiquinone oxidoreductase B16.6 subunit
DescriptionNADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13
Typepolypeptide(L)
FragmentUNP RESIDUES 7-144
Formula weight16132.570 Da
Number of molecules2
ID21
SourceMethod: Isolated from a natural source
Src id: 1
Common name: Human
Alt source flag: sample
Beg seq num: 1
End seq num: 138
NCBI taxonomy: ID:9606
Organism scientific: Homo sapiens
LinksUniProt: Q9P0J0, Sequence view
ID 22 : Complex I-AGGG,CI-AGGG,NADH-ubiquinone oxidoreductase AGGG subunit
DescriptionNADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 2, mitochondrial
Typepolypeptide(L)
FragmentUNP RESIDUES 39-97
Formula weight7468.270 Da
Number of molecules2
ID22
SourceMethod: Isolated from a natural source
Src id: 1
Common name: Human
Alt source flag: sample
Beg seq num: 1
End seq num: 59
NCBI taxonomy: ID:9606
Organism scientific: Homo sapiens
LinksUniProt: O95178, Sequence view
ID 23 : Complex I-B12,CI-B12,NADH-ubiquinone oxidoreductase B12 subunit
DescriptionNADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 3
Typepolypeptide(L)
FragmentUNP RESIDUES 10-89
Formula weight9261.605 Da
Number of molecules2
ID23
SourceMethod: Isolated from a natural source
Src id: 1
Common name: Human
Alt source flag: sample
Beg seq num: 1
End seq num: 80
NCBI taxonomy: ID:9606
Organism scientific: Homo sapiens
LinksUniProt: O43676, Sequence view
ID 24 : Complex I-SGDH,CI-SGDH,NADH-ubiquinone oxidoreductase SGDH subunit
DescriptionNADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 5, mitochondrial
Typepolypeptide(L)
FragmentUNP RESIDUES 52-189
Formula weight16573.160 Da
Number of molecules2
ID24
SourceMethod: Isolated from a natural source
Src id: 1
Common name: Human
Alt source flag: sample
Beg seq num: 1
End seq num: 138
NCBI taxonomy: ID:9606
Organism scientific: Homo sapiens
LinksUniProt: O43674, Sequence view
ID 25 : Complex I-B17,CI-B17,NADH-ubiquinone oxidoreductase B17 subunit
DescriptionNADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 6
Typepolypeptide(L)
FragmentUNP RESIDUES 3-126
Formula weight15008.635 Da
Number of molecules2
ID25
SourceMethod: Isolated from a natural source
Src id: 1
Common name: Human
Alt source flag: sample
Beg seq num: 1
End seq num: 124
NCBI taxonomy: ID:9606
Organism scientific: Homo sapiens
LinksUniProt: O95139, Sequence view
ID 26 : Complex I-ASHI,CI-ASHI,NADH-ubiquinone oxidoreductase ASHI subunit
DescriptionNADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8, mitochondrial
Typepolypeptide(L)
FragmentUNP RESIDUES 34-186
Formula weight18267.562 Da
Number of molecules2
ID26
SourceMethod: Isolated from a natural source
Src id: 1
Common name: Human
Alt source flag: sample
Beg seq num: 1
End seq num: 153
NCBI taxonomy: ID:9606
Organism scientific: Homo sapiens
LinksUniProt: O95169, Sequence view
ID 27 : Complex I-PDSW,CI-PDSW,NADH-ubiquinone oxidoreductase PDSW subunit
DescriptionNADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 10
Typepolypeptide(L)
FragmentUNP RESIDUES 1-171
Formula weight20721.650 Da
Number of molecules2
ID27
SourceMethod: Isolated from a natural source
Src id: 1
Common name: Human
Alt source flag: sample
Beg seq num: 1
End seq num: 171
NCBI taxonomy: ID:9606
Organism scientific: Homo sapiens
LinksUniProt: O96000, Sequence view
ID 28 : Complex I-ESSS,CI-ESSS,NADH-ubiquinone oxidoreductase ESSS subunit,Neuronal protein 17.3,p17.3
DescriptionNADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 11, mitochondrial
Typepolypeptide(L)
FragmentUNP RESIDUES 54-150
Formula weight11494.942 Da
Number of molecules2
ID28
SourceMethod: Isolated from a natural source
Src id: 1
Common name: Human
Alt source flag: sample
Beg seq num: 1
End seq num: 97
NCBI taxonomy: ID:9606
Organism scientific: Homo sapiens
LinksUniProt: Q9NX14, Sequence view
ID 29 : Complex I-KFYI,CI-KFYI,NADH-ubiquinone oxidoreductase KFYI subunit
DescriptionNADH dehydrogenase [ubiquinone] 1 subunit C1, mitochondrial
Typepolypeptide(L)
FragmentUNP RESIDUES 28-74
Formula weight5704.602 Da
Number of molecules2
ID29
SourceMethod: Isolated from a natural source
Src id: 1
Common name: Human
Alt source flag: sample
Beg seq num: 1
End seq num: 47
NCBI taxonomy: ID:9606
Organism scientific: Homo sapiens
LinksUniProt: O43677, Sequence view
ID 30 : Complex I-B14.5b,CI-B14.5b,Human lung cancer oncogene 1 protein,HLC-1,NADH-ubiquinone oxidoreductase subunit B14.5b
DescriptionNADH dehydrogenase [ubiquinone] 1 subunit C2
Typepolypeptide(L)
Formula weight14209.521 Da
Number of molecules2
ID30
SourceMethod: Isolated from a natural source
Src id: 1
Common name: Human
Alt source flag: sample
Beg seq num: 1
End seq num: 119
NCBI taxonomy: ID:9606
Organism scientific: Homo sapiens
LinksUniProt: O95298, Sequence view
ID 31 : Complex I-15 kDa,CI-15 kDa,NADH-ubiquinone oxidoreductase 15 kDa subunit
DescriptionNADH dehydrogenase [ubiquinone] iron-sulfur protein 5
Typepolypeptide(L)
FragmentUNP RESIDUES 2-105
Formula weight12314.254 Da
Number of molecules2
ID31
SourceMethod: Isolated from a natural source
Src id: 1
Common name: Human
Alt source flag: sample
Beg seq num: 1
End seq num: 104
NCBI taxonomy: ID:9606
Organism scientific: Homo sapiens
LinksUniProt: O43920, Sequence view
ID 32 : NADH-ubiquinone oxidoreductase chain 2
DescriptionNADH-ubiquinone oxidoreductase chain 2
Typepolypeptide(L)
Formula weight39007.656 Da
Number of molecules2
ID32
Ec1.6.5.3
SourceMethod: Isolated from a natural source
Src id: 1
Common name: Human
Alt source flag: sample
Beg seq num: 1
End seq num: 347
NCBI taxonomy: ID:9606
Organism scientific: Homo sapiens
LinksUniProt: Q4GRX1, Sequence view
ID 33 : NADH-ubiquinone oxidoreductase chain 3
DescriptionNADH-ubiquinone oxidoreductase chain 3
Typepolypeptide(L)
FragmentUNP RESIDUES 1-115
Formula weight13147.871 Da
Number of molecules2
ID33
Ec1.6.5.3
SourceMethod: Isolated from a natural source
Src id: 1
Common name: Human
Alt source flag: sample
Beg seq num: 1
End seq num: 115
NCBI taxonomy: ID:9606
Organism scientific: Homo sapiens
LinksUniProt: B9EE38, Sequence view
ID 34 : NADH-ubiquinone oxidoreductase chain 4L
DescriptionNADH-ubiquinone oxidoreductase chain 4L
Typepolypeptide(L)
FragmentUNP RESIDUES 1-97
Formula weight10702.086 Da
Number of molecules2
ID34
Ec1.6.5.3
SourceMethod: Isolated from a natural source
Src id: 1
Common name: Human
Alt source flag: sample
Beg seq num: 1
End seq num: 97
NCBI taxonomy: ID:9606
Organism scientific: Homo sapiens
LinksUniProt: V9JN72, Sequence view
ID 35 : NADH-ubiquinone oxidoreductase chain 5
DescriptionNADH-ubiquinone oxidoreductase chain 5
Typepolypeptide(L)
Formula weight67096.023 Da
Number of molecules2
ID35
Ec1.6.5.3
SourceMethod: Isolated from a natural source
Src id: 1
Common name: Human
Alt source flag: sample
Beg seq num: 1
End seq num: 603
NCBI taxonomy: ID:9606
Organism scientific: Homo sapiens
LinksUniProt: X5BVZ3, Sequence view
ID 36 : NADH-ubiquinone oxidoreductase chain 6
DescriptionNADH-ubiquinone oxidoreductase chain 6
Typepolypeptide(L)
Formula weight18660.979 Da
Number of molecules2
ID36
Ec1.6.5.3
SourceMethod: Isolated from a natural source
Src id: 1
Common name: Human
Alt source flag: sample
Beg seq num: 1
End seq num: 174
NCBI taxonomy: ID:9606
Organism scientific: Homo sapiens
LinksUniProt: Q8HAX7, Sequence view
ID 37 : Complex I-MNLL,CI-MNLL,NADH-ubiquinone oxidoreductase MNLL subunit
DescriptionNADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 1
Typepolypeptide(L)
FragmentUNP RESIDUES 3-58
Formula weight6741.883 Da
Number of molecules2
ID37
SourceMethod: Isolated from a natural source
Src id: 1
Common name: Human
Alt source flag: sample
Beg seq num: 1
End seq num: 56
NCBI taxonomy: ID:9606
Organism scientific: Homo sapiens
LinksUniProt: O75438, Sequence view
ID 38 : Complex I-B15,CI-B15,NADH-ubiquinone oxidoreductase B15 subunit
DescriptionNADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 4
Typepolypeptide(L)
Formula weight15100.399 Da
Number of molecules2
ID38
SourceMethod: Isolated from a natural source
Src id: 1
Common name: Human
Alt source flag: sample
Beg seq num: 1
End seq num: 128
NCBI taxonomy: ID:9606
Organism scientific: Homo sapiens
LinksUniProt: O95168, Sequence view
ID 39 : Complex I-B22,CI-B22,LYR motif-containing protein 3,NADH-ubiquinone oxidoreductase B22 subunit
DescriptionNADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 9
Typepolypeptide(L)
FragmentUNP RESIDUES 8-179
Formula weight21189.141 Da
Number of molecules2
ID39
SourceMethod: Isolated from a natural source
Src id: 1
Common name: Human
Alt source flag: sample
Beg seq num: 1
End seq num: 172
NCBI taxonomy: ID:9606
Organism scientific: Homo sapiens
LinksUniProt: Q9Y6M9, Sequence view
ID 40 : NADH-ubiquinone oxidoreductase chain 4
DescriptionNADH-ubiquinone oxidoreductase chain 4
Typepolypeptide(L)
Formula weight51689.688 Da
Number of molecules2
ID40
Ec1.6.5.3
SourceMethod: Isolated from a natural source
Src id: 1
Common name: Human
Alt source flag: sample
Beg seq num: 1
End seq num: 459
NCBI taxonomy: ID:9606
Organism scientific: Homo sapiens
LinksUniProt: B2XJG5, Sequence view
ID 41 : NADH-ubiquinone oxidoreductase chain 1
DescriptionNADH-ubiquinone oxidoreductase chain 1
Typepolypeptide(L)
Formula weight35621.215 Da
Number of molecules2
ID41
Ec1.6.5.3
SourceMethod: Isolated from a natural source
Src id: 1
Common name: Human
Alt source flag: sample
Beg seq num: 1
End seq num: 318
NCBI taxonomy: ID:9606
Organism scientific: Homo sapiens
LinksUniProt: H9PGF0, Sequence view
ID 42 : Complex I-19kD,CI-19kD,Complex I-PGIV,CI-PGIV,NADH-ubiquinone oxidoreductase 19 kDa subunit
DescriptionNADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8
Typepolypeptide(L)
FragmentUNP RESIDUES 4-172
Formula weight19853.736 Da
Number of molecules2
ID42
SourceMethod: Isolated from a natural source
Src id: 1
Common name: Human
Alt source flag: sample
Beg seq num: 1
End seq num: 169
NCBI taxonomy: ID:9606
Organism scientific: Homo sapiens
LinksUniProt: P51970, Sequence view
ID 43 : Cell adhesion protein SQM1,Complex I-B18,CI-B18,NADH-ubiquinone oxidoreductase B18 subunit
DescriptionNADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 7
Typepolypeptide(L)
FragmentUNP RESIDUES 3-124
Formula weight14997.401 Da
Number of molecules2
ID43
SourceMethod: Isolated from a natural source
Src id: 1
Common name: Human
Alt source flag: sample
Beg seq num: 1
End seq num: 122
NCBI taxonomy: ID:9606
Organism scientific: Homo sapiens
LinksUniProt: P17568, Sequence view
ID 44 : Complex I-42kD,CI-42kD,NADH-ubiquinone oxidoreductase 42 kDa subunit
DescriptionNADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial
Typepolypeptide(L)
Formula weight37200.270 Da
Number of molecules2
ID44
SourceMethod: Isolated from a natural source
Src id: 1
Common name: Human
Alt source flag: sample
Beg seq num: 1
End seq num: 320
NCBI taxonomy: ID:9606
Organism scientific: Homo sapiens
LinksUniProt: O95299, Sequence view
ID 45 : Cytochrome c oxidase polypeptide I
DescriptionCytochrome c oxidase subunit 1
Typepolypeptide(L)
Formula weight57065.844 Da
Number of molecules2
ID45
Ec1.9.3.1
SourceMethod: Isolated from a natural source
Src id: 1
Common name: Bovine
Alt source flag: sample
Beg seq num: 1
End seq num: 514
NCBI taxonomy: ID:9913
Organism scientific: Bos taurus

LinksUniProt: P00396, Sequence view
ID 46 : Cytochrome c oxidase polypeptide II
DescriptionCytochrome c oxidase subunit 2
Typepolypeptide(L)
Formula weight26040.393 Da
Number of molecules2
ID46
SourceMethod: Isolated from a natural source
Src id: 1
Common name: Bovine
Alt source flag: sample
Beg seq num: 1
End seq num: 227
NCBI taxonomy: ID:9913
Organism scientific: Bos taurus
LinksUniProt: P68530, Sequence view
ID 47 : Cytochrome c oxidase polypeptide III
DescriptionCytochrome c oxidase subunit 3
Typepolypeptide(L)
Formula weight29957.627 Da
Number of molecules2
ID47
SourceMethod: Isolated from a natural source
Src id: 1
Common name: Bovine
Alt source flag: sample
Beg seq num: 1
End seq num: 261
NCBI taxonomy: ID:9913
Organism scientific: Bos taurus
LinksUniProt: P00415, Sequence view
ID 48 : Cytochrome c oxidase polypeptide IV,Cytochrome c oxidase subunit IV isoform 1,COX IV-1
DescriptionCytochrome c oxidase subunit 4 isoform 1, mitochondrial
Typepolypeptide(L)
FragmentUNP RESIDUES 26-169
Formula weight16913.367 Da
Number of molecules2
ID48
SourceMethod: Isolated from a natural source
Src id: 1
Common name: Bovine
Alt source flag: sample
Beg seq num: 1
End seq num: 144
NCBI taxonomy: ID:9913
Organism scientific: Bos taurus
LinksUniProt: P00423, Sequence view
ID 49 : Cytochrome c oxidase polypeptide Va
DescriptionCytochrome c oxidase subunit 5A, mitochondrial
Typepolypeptide(L)
Formula weight12453.081 Da
Number of molecules2
ID49
SourceMethod: Isolated from a natural source
Src id: 1
Common name: Bovine
Alt source flag: sample
Beg seq num: 1
End seq num: 109
NCBI taxonomy: ID:9913
Organism scientific: Bos taurus
LinksUniProt: P00426, Sequence view
ID 50 : Cytochrome c oxidase polypeptide VIa,Cytochrome c oxidase polypeptide Vb
DescriptionCytochrome c oxidase subunit 5B, mitochondrial
Typepolypeptide(L)
Formula weight10684.038 Da
Number of molecules2
ID50
SourceMethod: Isolated from a natural source
Src id: 1
Common name: Bovine
Alt source flag: sample
Beg seq num: 1
End seq num: 98
NCBI taxonomy: ID:9913
Organism scientific: Bos taurus
LinksUniProt: P00428, Sequence view
ID 51 : Cytochrome c oxidase polypeptide VIa-heart,COXVIAH,Cytochrome c oxidase polypeptide VIb
DescriptionCytochrome c oxidase subunit 6A2, mitochondrial
Typepolypeptide(L)
FragmentUNP RESIDUES 13-96
Formula weight9452.687 Da
Number of molecules2
ID51
SourceMethod: Isolated from a natural source
Src id: 1
Common name: Bovine
Alt source flag: sample
Beg seq num: 1
End seq num: 84
NCBI taxonomy: ID:9913
Organism scientific: Bos taurus
LinksUniProt: P07471, Sequence view
ID 52 : Cytochrome c oxidase polypeptide VII,Cytochrome c oxidase subunit AED,Cytochrome c oxidase subunit VIb isoform 1,COX VIb-1
DescriptionCytochrome c oxidase subunit 6B1
Typepolypeptide(L)
FragmentUNP RESIDUES 12-86
Formula weight8925.979 Da
Number of molecules2
ID52
SourceMethod: Isolated from a natural source
Src id: 1
Common name: Bovine
Alt source flag: sample
Beg seq num: 1
End seq num: 75
NCBI taxonomy: ID:9913
Organism scientific: Bos taurus
LinksUniProt: P00429, Sequence view
ID 53 : Cytochrome c oxidase polypeptide VIc,Cytochrome c oxidase subunit STA
DescriptionCytochrome c oxidase subunit 6C
Typepolypeptide(L)
Formula weight8494.982 Da
Number of molecules2
ID53
SourceMethod: Isolated from a natural source
Src id: 1
Common name: Bovine
Alt source flag: sample
Beg seq num: 1
End seq num: 73
NCBI taxonomy: ID:9913
Organism scientific: Bos taurus
LinksUniProt: P04038, Sequence view
ID 54 : Cytochrome c oxidase subunit VIIIc,VIIIC,Cytochrome c oxidase subunit VIIa-heart,Cytochrome c oxidase subunit VIIa-H,Cytochrome c oxidase subunit VIIa-muscle,Cytochrome c oxidase subunit VIIa-M
DescriptionCytochrome c oxidase subunit 7A1, mitochondrial
Typepolypeptide(L)
FragmentUNP RESIDUES 22-77
Formula weight6286.220 Da
Number of molecules2
ID54
SourceMethod: Isolated from a natural source
Src id: 1
Common name: Bovine
Alt source flag: sample
Beg seq num: 1
End seq num: 56
NCBI taxonomy: ID:9913
Organism scientific: Bos taurus
LinksUniProt: P07470, Sequence view
ID 55 : Cytochrome c oxidase polypeptide VIIb,IHQ
DescriptionCytochrome c oxidase subunit 7B, mitochondrial
Typepolypeptide(L)
FragmentUNP RESIDUES 30-78
Formula weight5442.168 Da
Number of molecules2
ID55
SourceMethod: Isolated from a natural source
Src id: 1
Common name: Bovine
Alt source flag: sample
Beg seq num: 1
End seq num: 49
NCBI taxonomy: ID:9913
Organism scientific: Bos taurus
LinksUniProt: P13183, Sequence view
ID 56 : Cytochrome c oxidase polypeptide VIIIA,Cytochrome c oxidase polypeptide VIIc
DescriptionCytochrome c oxidase subunit 7C, mitochondrial
Typepolypeptide(L)
Formula weight5449.396 Da
Number of molecules2
ID56
SourceMethod: Isolated from a natural source
Src id: 1
Common name: Bovine
Alt source flag: sample
Beg seq num: 1
End seq num: 47
NCBI taxonomy: ID:9913
Organism scientific: Bos taurus
LinksUniProt: P00430, Sequence view
ID 57 : Cytochrome c oxidase polypeptide VIII-heart,Cytochrome c oxidase subunit 8-1,Cytochrome c oxidase subunit 8H,IX,VIIIb
DescriptionCytochrome c oxidase subunit 8B, mitochondrial
Typepolypeptide(L)
FragmentUNP RESIDUES 25-67
Formula weight4738.523 Da
Number of molecules2
ID57
SourceMethod: Isolated from a natural source
Src id: 1
Common name: Bovine
Alt source flag: sample
Beg seq num: 1
End seq num: 43
NCBI taxonomy: ID:9913
Organism scientific: Bos taurus
LinksUniProt: P10175, Sequence view
ID 58 : Complex III subunit 8,Complex III subunit VIII,Ubiquinol-cytochrome c reductase complex 9.5 kDa protein,Ubiquinol-cytochrome c reductase complex ubiquinone-binding protein QP-C
DescriptionCytochrome b-c1 complex subunit 8
Typepolypeptide(L)
Formula weight9791.181 Da
Number of molecules2
ID58
SourceMethod: Isolated from a natural source
Src id: 1
Common name: Human
Alt source flag: sample
Beg seq num: 1
End seq num: 81
NCBI taxonomy: ID:9606
Organism scientific: Homo sapiens
LinksUniProt: O14949, Sequence view
ID 59 : Complex III subunit 5,Cytochrome b-c1 complex subunit 5,Rieske iron-sulfur protein,RISP,Ubiquinol-cytochrome c reductase iron-sulfur subunit
DescriptionCytochrome b-c1 complex subunit Rieske, mitochondrial
Typepolypeptide(L)
FragmentUNP RESIDUES 1-57
Formula weight5893.814 Da
Number of molecules2
ID59
Ec1.10.2.2
SourceMethod: Isolated from a natural source
Src id: 1
Common name: Human
Alt source flag: sample
Beg seq num: 1
End seq num: 57
NCBI taxonomy: ID:9606
Organism scientific: Homo sapiens
LinksUniProt: P47985, Sequence view
ID 60 : Complex III subunit 5,Cytochrome b-c1 complex subunit 5,Rieske iron-sulfur protein,RISP,Ubiquinol-cytochrome c reductase iron-sulfur subunit
DescriptionCytochrome b-c1 complex subunit Rieske, mitochondrial
Typepolypeptide(L)
Formula weight21645.578 Da
Number of molecules2
ID60
Ec1.10.2.2
SourceMethod: Isolated from a natural source
Src id: 1
Common name: Human
Alt source flag: sample
Beg seq num: 1
End seq num: 196
NCBI taxonomy: ID:9606
Organism scientific: Homo sapiens
LinksUniProt: P47985, Sequence view
ID 61 : Complex III subunit 9,Complex III subunit X,Cytochrome c1 non-heme 7 kDa protein,Ubiquinol-cytochrome c reductase complex 7.2 kDa protein
DescriptionCytochrome b-c1 complex subunit 9
Typepolypeptide(L)
Formula weight7189.299 Da
Number of molecules2
ID61
SourceMethod: Isolated from a natural source
Src id: 1
Common name: Human
Alt source flag: sample
Beg seq num: 1
End seq num: 62
NCBI taxonomy: ID:9606
Organism scientific: Homo sapiens
LinksUniProt: Q9UDW1, Sequence view
ID 62 : Complex III subunit 6,Complex III subunit VIII,Cytochrome c1 non-heme 11 kDa protein,Mitochondrial hinge protein,Ubiquinol-cytochrome c reductase complex 11 kDa protein
DescriptionCytochrome b-c1 complex subunit 6, mitochondrial
Typepolypeptide(L)
FragmentUNP RESIDUES 18-91
Formula weight8861.742 Da
Number of molecules2
ID62
SourceMethod: Isolated from a natural source
Src id: 1
Common name: Human
Alt source flag: sample
Beg seq num: 1
End seq num: 74
NCBI taxonomy: ID:9606
Organism scientific: Homo sapiens
LinksUniProt: P07919, Sequence view
ID 63 : Complex III subunit 7,Complex III subunit VII,QP-C,Ubiquinol-cytochrome c reductase complex 14 kDa protein
DescriptionCytochrome b-c1 complex subunit 7
Typepolypeptide(L)
FragmentUNP RESIDUES 6-111
Formula weight13037.842 Da
Number of molecules2
ID63
SourceMethod: Isolated from a natural source
Src id: 1
Common name: Human
Alt source flag: sample
Beg seq num: 1
End seq num: 106
NCBI taxonomy: ID:9606
Organism scientific: Homo sapiens
LinksUniProt: P14927, Sequence view
ID 64 : Complex III subunit 10,Complex III subunit XI,Ubiquinol-cytochrome c reductase complex 6.4 kDa protein
DescriptionCytochrome b-c1 complex subunit 10
Typepolypeptide(L)
FragmentUNP RESIDUES 2-52
Formula weight5958.912 Da
Number of molecules2
ID64
SourceMethod: Isolated from a natural source
Src id: 1
Common name: Human
Alt source flag: sample
Beg seq num: 1
End seq num: 51
NCBI taxonomy: ID:9606
Organism scientific: Homo sapiens
LinksUniProt: O14957, Sequence view
ID 65 : Complex III subunit 4,Complex III subunit IV,Cytochrome b-c1 complex subunit 4,Ubiquinol-cytochrome-c reductase complex cytochrome c1 subunit,Cytochrome c-1
DescriptionCytochrome c1, heme protein, mitochondrial
Typepolypeptide(L)
Formula weight27388.395 Da
Number of molecules2
ID65
SourceMethod: Isolated from a natural source
Src id: 1
Common name: Human
Alt source flag: sample
Beg seq num: 1
End seq num: 241
NCBI taxonomy: ID:9606
Organism scientific: Homo sapiens
LinksUniProt: P08574, Sequence view
ID 66 : Complex III subunit 3,Complex III subunit III,Cytochrome b-c1 complex subunit 3,Ubiquinol-cytochrome-c reductase complex cytochrome b subunit
DescriptionCytochrome b
Typepolypeptide(L)
FragmentUNP RESIDUES 2-479
Formula weight42543.016 Da
Number of molecules2
ID66
SourceMethod: Isolated from a natural source
Src id: 1
Common name: Human
Alt source flag: sample
Beg seq num: 1
End seq num: 378
NCBI taxonomy: ID:9606
Organism scientific: Homo sapiens
LinksUniProt: P00156, Sequence view
ID 67 : Complex III subunit 2,Core protein II,Ubiquinol-cytochrome-c reductase complex core protein 2
DescriptionCytochrome b-c1 complex subunit 2, mitochondrial
Typepolypeptide(L)
FragmentUNP RESIDUES 35-453
Formula weight44946.582 Da
Number of molecules2
ID67
SourceMethod: Isolated from a natural source
Src id: 1
Common name: Human
Alt source flag: sample
Beg seq num: 1
End seq num: 419
NCBI taxonomy: ID:9606
Organism scientific: Homo sapiens
LinksUniProt: P22695, Sequence view
ID 68 : Complex III subunit 1,Core protein I,Ubiquinol-cytochrome-c reductase complex core protein 1
DescriptionCytochrome b-c1 complex subunit 1, mitochondrial
Typepolypeptide(L)
Formula weight49181.430 Da
Number of molecules2
ID68
SourceMethod: Isolated from a natural source
Src id: 1
Common name: Human
Alt source flag: sample
Beg seq num: 1
End seq num: 446
NCBI taxonomy: ID:9606
Organism scientific: Homo sapiens
LinksUniProt: P31930, Sequence view
ID 69 : IRON/SULFUR CLUSTER
DescriptionIRON/SULFUR CLUSTER
Typenon-polymer
Formula weight351.640 Da
Number of molecules12
ID69
SourceMethod: Obtained synthetically
ID 70 : FLAVIN MONONUCLEOTIDE
DescriptionFLAVIN MONONUCLEOTIDE
Typenon-polymer
Formula weight456.344 Da
Number of molecules2
ID70
SourceMethod: Obtained synthetically
ID 71 : (9R,11S)-9-({[(1S)-1-HYDROXYHEXADECYL]OXY}METHYL)-2,2-DIMETHYL-5,7,10-TRIOXA-2LAMBDA~5~-AZA-6LAMBDA~5~-PHOSPHAOCTACOSANE-6,6,11-TRIOL
Description(9R,11S)-9-({[(1S)-1-HYDROXYHEXADECYL]OXY}METHYL)-2,2-DIMETHYL-5,7,10-TRIOXA-2LAMBDA~5~-AZA-6LAMBDA~5~-PHOSPHAOCTACOSANE-6,6,11-TRIOL
Typenon-polymer
Formula weight767.132 Da
Number of molecules21
ID71
SourceMethod: Obtained synthetically
ID 72 : S-[2-({N-[(2R)-2-hydroxy-3,3-dimethyl-4-(phosphonooxy)butanoyl]-beta-alanyl}amino)ethyl] dodecanethioate
DescriptionS-[2-({N-[(2R)-2-hydroxy-3,3-dimethyl-4-(phosphonooxy)butanoyl]-beta-alanyl}amino)ethyl] dodecanethioate
Typenon-polymer
Formula weight540.651 Da
Number of molecules4
ID72
SourceMethod: Obtained synthetically
ID 73 : NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
DescriptionNADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
Typenon-polymer
Formula weight745.421 Da
Number of molecules2
ID73
SourceMethod: Obtained synthetically
ID 74 : FE2/S2 (INORGANIC) CLUSTER
DescriptionFE2/S2 (INORGANIC) CLUSTER
Typenon-polymer
Formula weight175.820 Da
Number of molecules6
ID74
SourceMethod: Obtained synthetically
ID 75 : CARDIOLIPIN
DescriptionCARDIOLIPIN
Typenon-polymer
Formula weight1464.043 Da
Number of molecules19
ID75
SourceMethod: Obtained synthetically
ID 76 : 1,2-Dioleoyl-sn-glycero-3-phosphoethanolamine
Description1,2-Dioleoyl-sn-glycero-3-phosphoethanolamine
Typenon-polymer
Formula weight749.073 Da
Number of molecules14
ID76
SourceMethod: Obtained synthetically
ID 77 : COPPER (II) ION
DescriptionCOPPER (II) ION
Typenon-polymer
Formula weight63.546 Da
Number of molecules6
ID77
SourceMethod: Obtained synthetically
ID 78 : MAGNESIUM ION
DescriptionMAGNESIUM ION
Typenon-polymer
Formula weight24.305 Da
Number of molecules2
ID78
SourceMethod: Obtained synthetically
ID 79 : HEME-A
DescriptionHEME-A
Typenon-polymer
Formula weight852.837 Da
Number of molecules4
ID79
SourceMethod: Obtained synthetically
ID 80 : ZINC ION
DescriptionZINC ION
Typenon-polymer
Formula weight65.409 Da
Number of molecules2
ID80
SourceMethod: Obtained synthetically
ID 81 : HEME C
DescriptionHEME C
Typenon-polymer
Formula weight618.503 Da
Number of molecules2
ID81
SourceMethod: Obtained synthetically
ID 82 : PROTOPORPHYRIN IX CONTAINING FE
DescriptionPROTOPORPHYRIN IX CONTAINING FE
Typenon-polymer
Formula weight616.487 Da
Number of molecules4
ID82
SourceMethod: Obtained synthetically
Sample
Entity assembly
Entity id list1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63, 64, 65, 66, 67, 68
NameHuman respiratory chain megacomplex-I2III2IV2
SourceNATURAL
TypeCOMPLEX
Buffer
Specimen id1
PH7.4
Experiment
Aggregation statePARTICLE
Reconstruction methodSINGLE PARTICLE
Vitrification
Specimen id1
Cryogen nameETHANE
Experiment
MethodELECTRON MICROSCOPY
Electron Microscopy
Imaging
MicroscopeModel: FEI TITAN KRIOS
Electron gun
Electron sourceFIELD EMISSION GUN
Accelerating voltage300 kV
Illumination modeOTHER
Lens
ModeBRIGHT FIELD
Processing
Single particle entity
Image processing id1
Point symmetryC1
3D reconstruction
Image processing id1
Number of particles8600
Resolution17.4 A
Resolution methodFSC 0.143 CUT-OFF
Symmetry typePOINT
Download
PDB format
Allpdb5xti.ent.gz
pdb5xti.ent (uncompressed file)
Header onlypdb5xti.ent.gz
mmCIF format
mmCIF5xti.cif.gz
XML format
All5xti.xml.gz
No-atom5xti-noatom.xml.gz
Ext-atom5xti-extatom.xml.gz
Movie files
movie #1
.mp4 (H.264/MPEG-4 AVC format), 3.3 MB
.webm (WebM/VP8 format), 6.6 MB
movie #2
.mp4 (H.264/MPEG-4 AVC format), 3.7 MB
.webm (WebM/VP8 format), 6.7 MB