eF-site ID 8pch-A PDB Code 8pch Chain A click to enlarge Title CRYSTAL STRUCTURE OF PORCINE CATHEPSIN H DETERMINED AT 2.1 ANGSTROM RESOLUTION: LOCATION OF THE MINI-CHAIN C-TERMINAL CARBOXYL GROUP DEFINES CATHEPSIN H AMINOPEPTIDASE FUNCTION Classification HYDROLASE Compound CATHEPSIN H Source ORGANISM_COMMON: pig; ORGANISM_SCIENTIFIC: Sus scrofa; Sequence A:  YPPSMDWRKKGNFVSPVKNQGSCGSCWTFSTTGALESAVA IATGKMLSLAEQQLVDCAQNFNNHGCQGGLPSQAFEYIRY NKGIMGEDTYPYKGQDDHCKFQPDKAIAFVKDVANITMND EEAMVEAVALYNPVSFAFEVTNDFLMYRKGIYSSTSCHKT PDKVNHAVLAVGYGEENGIPYWIVKNSWGPQWGMNGYFLI ERGKNMCGLAACASYPIPLV Description Functional site 1) chain A residue 25 type sequence C description ACTIVE SITE. source : ACT 2) chain A residue 159 type sequence H description ACTIVE SITE. source : ACT 3) chain A residue 19 type catalytic sequence Q description 682 source MCSA : MCSA1 4) chain A residue 25 type catalytic sequence C description 682 source MCSA : MCSA1 5) chain A residue 159 type catalytic sequence H description 682 source MCSA : MCSA1 6) chain A residue 159 type CARBOHYD sequence H description N-linked (GlcNAc...) asparagine => ECO:0000255 source Swiss-Prot : SWS_FT_FI1 7) chain A residue 175 type CARBOHYD sequence N description N-linked (GlcNAc...) asparagine => ECO:0000255 source Swiss-Prot : SWS_FT_FI1 8) chain A residue 112 type CARBOHYD sequence N description N-linked (GlcNAc...) asparagine => ECO:0000255 source Swiss-Prot : SWS_FT_FI2 9) chain A residue 19-30 type prosite sequence QGSCGSCWTFST description THIOL_PROTEASE_CYS Eukaryotic thiol (cysteine) proteases cysteine active site. QGsCGSCWTfST source prosite : PS00139 10) chain A residue 157-167 type prosite sequence VNHAVLAVGYG description THIOL_PROTEASE_HIS Eukaryotic thiol (cysteine) proteases histidine active site. VNHAVLAVGYG source prosite : PS00639 11) chain A residue 170-189 type prosite sequence YWIVKNSWGPQWGMNGYFLI description THIOL_PROTEASE_ASN Eukaryotic thiol (cysteine) proteases asparagine active site. YWIvKNSWgpqWGmnGYFlI source prosite : PS00640

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