eF-site ID 7ins-A PDB Code 7ins Chain A click to enlarge Title STRUCTURE OF PORCINE INSULIN COCRYSTALLIZED WITH CLUPEINE Z Classification HORMONE Compound INSULIN (CHAIN A) Source Sus scrofa (Pig) (7INS) Sequence A:  GIVEQCCTSICSLYQLENYCN Description Functional site 1) chain A residue 6 type sequence C description M-CRESOL BINDING SITE. OH BINDS ON EACH MONOMER TO OA6 AND NHA11 VIA HYDROGEN BOND. IT IS BOUNDED BY B10 OF SAME MONOMER AND B5 OF A DIFFERENT ONE WITHIN THE SAME TRIMER. source : MCR 2) chain A residue 11 type sequence C description M-CRESOL BINDING SITE. OH BINDS ON EACH MONOMER TO OA6 AND NHA11 VIA HYDROGEN BOND. IT IS BOUNDED BY B10 OF SAME MONOMER AND B5 OF A DIFFERENT ONE WITHIN THE SAME TRIMER. source : MCR 3) chain A residue 6 type sequence C description BINDING SITE FOR RESIDUE CRS A 22 source : AC4 4) chain A residue 10 type sequence I description BINDING SITE FOR RESIDUE CRS A 22 source : AC4 5) chain A residue 11 type sequence C description BINDING SITE FOR RESIDUE CRS A 22 source : AC4 6) chain A residue 6-20 type prosite sequence CCTSICSLYQLENYC description INSULIN Insulin family signature. CCTSiCSlyqLenyC source prosite : PS00262

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