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eF-site ID
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7cjf-ABC |
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PDB Code
|
7cjf |
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Chain
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A, B, C |
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click to enlarge
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Title
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Crystal structure of SARS-CoV-2 RBD in complex with a neutralizing antibody Fab |
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Classification
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VIRAL PROTEIN |
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Compound
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antibody heavy chain |
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Source
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(SPIKE_SARS2) |
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Sequence
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A: |
EVQLVESGGGLIQPGGSLRLSCAASGFIVSSNYMSWVRQA
PGKGLEWVSIIYSGGSTFYADSVKGRFTISRDNSKNTLYL
QMNSLRVEDTAVYYCARDLQELGSLDYWGQGTLVTVSSAS
TKGPSVFPLAPCSRSTSESTAALGCLVKDYFPEPVTVSWN
SGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTKTYT
CNVDHKPSNTKVDKRVESKY
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| B: |
DIQMTQSPSSVSASVGDRVTITCRASQGISSWLAWYQQKP
GKAPKLLIYAASSLQSGVPSRFSGSGSGTDFTLTISSLQP
EDFATYYCQEANSFPYTFGQGTKLEIKRTVAAPSVFIFPP
SDEQLKSGTASVVCLLNNFYPREAKVQWKVDNALQSGNSQ
ESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQG
LSSPVTKSFNRGE
|
| C: |
NLCPFGEVFNATRFASVYAWNRKRISNCVADYSVLYNSAS
FSTFKCYGVSPTKLNDLCFTNVYADSFVIRGDEVRQIAPG
QTGKIADYNYKLPDDFTGCVIAWNSNNLDSKVGGNYNYLY
RLFRKSNLKPFERDISTEIYQAGSTPCNGVEGFNCYFPLQ
SYGFQPTNGVGYQPYRVVVLSFELLHAPATVCGP
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Description
|
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Functional site
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|
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1)
|
chain |
C |
| residue |
343 |
| type |
CARBOHYD |
| sequence |
N
|
| description |
N-linked (GlcNAc...) (complex) asparagine; by host => ECO:0000255|HAMAP-Rule:MF_04099, ECO:0000269|PubMed:32155444, ECO:0000269|PubMed:32363391, ECO:0000269|PubMed:32366695, ECO:0000269|PubMed:32979942
|
| source |
Swiss-Prot : SWS_FT_FI1
|
|
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2)
|
chain |
A |
| residue |
199-205 |
| type |
prosite |
| sequence |
YTCNVDH
|
| description |
IG_MHC Immunoglobulins and major histocompatibility complex proteins signature. YTCNVDH
|
| source |
prosite : PS00290
|
|
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3)
|
chain |
B |
| residue |
192-198 |
| type |
prosite |
| sequence |
YACEVTH
|
| description |
IG_MHC Immunoglobulins and major histocompatibility complex proteins signature. YTCNVDH
|
| source |
prosite : PS00290
|
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