eF-site ID 6vo2-A PDB Code 6vo2 Chain A click to enlarge Title Crystal structure of Staphylococcus aureus ketol-acid reductoisomerase in complex with Mg, NADPH and inhibitor. Classification METAL BINDING PROTEIN Compound Ketol-acid reductoisomerase (NADP(+)) Source (A0A145BYP4_STAAU) Sequence A:  TTVYYDQDVKTDALQGKKIAVVGYGSQGHAHAQNLKDNGY DVVIGIRPGRSFDKAKEDGFDVFPVAEAVKQADVIMVLLP DEIQGDVYKNEIEPNLEKHNALAFAHGFNIHFGVIQPPAD VDVFLVAPKGPGHLVRRTFVEGSAVPSLFGIQQDASGQAR NIALSYAKGIGATRAGVIETTFKEETETDLFGEQAVLCGG VSKLIQSGFETLVEAGYQPELAYFEVLHEMKLIVDLMYEG GMENVRYSISNTAEFGDYVSGPRVITPDVKENMKAVLTDI QNGNFSNRFIEDNKNGFKEFYKLREEQHGHQIEKVGRELR EMMPFI Description Functional site 1) chain A residue 190 type sequence D description binding site for residue MG A 401 source : AC1 2) chain A residue 194 type sequence E description binding site for residue MG A 401 source : AC1 3) chain A residue 190 type sequence D description binding site for residue MG A 402 source : AC2 4) chain A residue 230 type sequence E description binding site for residue R67 A 403 source : AC3 5) chain A residue 234 type sequence I description binding site for residue R67 A 403 source : AC3 6) chain A residue 250 type sequence I description binding site for residue R67 A 403 source : AC3 7) chain A residue 251 type sequence S description binding site for residue R67 A 403 source : AC3 8) chain A residue 254 type sequence A description binding site for residue R67 A 403 source : AC3 9) chain A residue 25 type sequence Y description binding site for residue NDP A 404 source : AC4 10) chain A residue 26 type sequence G description binding site for residue NDP A 404 source : AC4 11) chain A residue 27 type sequence S description binding site for residue NDP A 404 source : AC4 12) chain A residue 28 type sequence Q description binding site for residue NDP A 404 source : AC4 13) chain A residue 47 type sequence I description binding site for residue NDP A 404 source : AC4 14) chain A residue 48 type sequence R description binding site for residue NDP A 404 source : AC4 15) chain A residue 52 type sequence S description binding site for residue NDP A 404 source : AC4 16) chain A residue 79 type sequence L description binding site for residue NDP A 404 source : AC4 17) chain A residue 80 type sequence L description binding site for residue NDP A 404 source : AC4 18) chain A residue 81 type sequence P description binding site for residue NDP A 404 source : AC4 19) chain A residue 82 type sequence D description binding site for residue NDP A 404 source : AC4 20) chain A residue 85 type sequence Q description binding site for residue NDP A 404 source : AC4 21) chain A residue 88 type sequence V description binding site for residue NDP A 404 source : AC4 22) chain A residue 106 type sequence A description binding site for residue NDP A 404 source : AC4 23) chain A residue 107 type sequence H description binding site for residue NDP A 404 source : AC4 24) chain A residue 131 type sequence G description binding site for residue NDP A 404 source : AC4 25) chain A residue 132 type sequence P description binding site for residue NDP A 404 source : AC4 26) chain A residue 133 type sequence G description binding site for residue NDP A 404 source : AC4 27) chain A residue 131 type sequence G description binding site for residue R67 B 403 source : AC7 28) chain A residue 132 type sequence P description binding site for residue R67 B 403 source : AC7 29) chain A residue 190 type sequence D description binding site for residue R67 B 403 source : AC7 30) chain A residue 194 type sequence E description binding site for residue R67 B 403 source : AC7 31) chain A residue 249 type sequence S description binding site for residue NDP B 404 source : AC8 32) chain A residue 250 type sequence I description binding site for residue NDP B 404 source : AC8 33) chain A residue 251 type sequence S description binding site for residue NDP B 404 source : AC8 34) chain A residue 107 type ACT_SITE sequence H description ACT_SITE => ECO:0000255|HAMAP-Rule:MF_00435 source Swiss-Prot : SWS_FT_FI1 35) chain A residue 251 type BINDING sequence S description BINDING => ECO:0000255|HAMAP-Rule:MF_00435 source Swiss-Prot : SWS_FT_FI2 36) chain A residue 52 type BINDING sequence S description BINDING => ECO:0000255|HAMAP-Rule:MF_00435 source Swiss-Prot : SWS_FT_FI2 37) chain A residue 82 type BINDING sequence D description BINDING => ECO:0000255|HAMAP-Rule:MF_00435 source Swiss-Prot : SWS_FT_FI2 38) chain A residue 133 type BINDING sequence G description BINDING => ECO:0000255|HAMAP-Rule:MF_00435 source Swiss-Prot : SWS_FT_FI2 39) chain A residue 190 type BINDING sequence D description BINDING => ECO:0000255|HAMAP-Rule:MF_00435 source Swiss-Prot : SWS_FT_FI2 40) chain A residue 194 type BINDING sequence E description BINDING => ECO:0000255|HAMAP-Rule:MF_00435 source Swiss-Prot : SWS_FT_FI2 41) chain A residue 226 type BINDING sequence E description BINDING => ECO:0000255|HAMAP-Rule:MF_00435 source Swiss-Prot : SWS_FT_FI2 42) chain A residue 230 type BINDING sequence E description BINDING => ECO:0000255|HAMAP-Rule:MF_00435 source Swiss-Prot : SWS_FT_FI2 43) chain A residue 25 type BINDING sequence Y description BINDING => ECO:0000255|HAMAP-Rule:MF_00435 source Swiss-Prot : SWS_FT_FI2 44) chain A residue 48 type BINDING sequence R description BINDING => ECO:0000255|HAMAP-Rule:MF_00435 source Swiss-Prot : SWS_FT_FI2

Display surface Download Links