|
|
eF-site ID
|
6tq2-.AAA |
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PDB Code
|
6tq2 |
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Chain
|
AAA |
|
click to enlarge
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Title
|
N-TERMINAL BROMODOMAIN OF HUMAN BRD2 WITH 5-(4-(4-fluorophenyl)-1H-imidazol-5-yl)-1-methylpyridin-2(1H)-one |
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Classification
|
TRANSCRIPTION |
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Compound
|
Bromodomain-containing protein 2 |
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Source
|
(BRD2_HUMAN) |
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Sequence
|
AAA: |
VTNQLQYLHKVVMKALWKHQFAWPFRQPVDAVKLGLPDYH
KIIKQPMDMGTIKRRLENNYYWAASECMQDFNTMFTNCYI
YNKPTDDIVLMAQTLEKIFLQKVASMPQEEQE
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Description
|
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Functional site
|
|
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1)
|
chain |
AAA |
| residue |
96-155 |
| type |
prosite |
| sequence |
AWPFRQPVDAVKLGLPDYHKIIKQPMDMGTIKRRLENNYY
WAASECMQDFNTMFTNCYIY
|
| description |
BROMODOMAIN_1 Bromodomain signature. AwpFrqpvDavklglpDYHkiIkqpMdmgtIkrrlenny..Ywaasecmqdfnt.MftNCyiY
|
| source |
prosite : PS00633
|
|
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2)
|
chain |
AAA |
| residue |
112 |
| type |
BINDING |
| sequence |
D
|
| description |
BINDING => ECO:0000269|PubMed:37731000, ECO:0007744|PDB:8SB6
|
| source |
Swiss-Prot : SWS_FT_FI1
|
|
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3)
|
chain |
AAA |
| residue |
155 |
| type |
BINDING |
| sequence |
Y
|
| description |
BINDING => ECO:0000269|PubMed:37731000, ECO:0007744|PDB:8SB6
|
| source |
Swiss-Prot : SWS_FT_FI1
|
|
|
4)
|
chain |
AAA |
| residue |
156 |
| type |
BINDING |
| sequence |
N
|
| description |
BINDING => ECO:0000269|PubMed:37731000, ECO:0007744|PDB:8SB6
|
| source |
Swiss-Prot : SWS_FT_FI1
|
|
|
5)
|
chain |
AAA |
| residue |
157 |
| type |
BINDING |
| sequence |
K
|
| description |
BINDING => ECO:0000269|PubMed:37731000, ECO:0007744|PDB:8SB6
|
| source |
Swiss-Prot : SWS_FT_FI1
|
|
|
6)
|
chain |
AAA |
| residue |
160 |
| type |
BINDING |
| sequence |
D
|
| description |
BINDING => ECO:0000269|PubMed:20048151, ECO:0007744|PDB:2DVQ, ECO:0007744|PDB:2DVS
|
| source |
Swiss-Prot : SWS_FT_FI2
|
|
|
7)
|
chain |
AAA |
| residue |
161 |
| type |
BINDING |
| sequence |
D
|
| description |
BINDING => ECO:0000269|PubMed:20048151, ECO:0007744|PDB:2DVQ, ECO:0007744|PDB:2DVS
|
| source |
Swiss-Prot : SWS_FT_FI2
|
|
|
|