eF-site ID 6tim-B PDB Code 6tim Chain B click to enlarge Title THE ADAPTABILITY OF THE ACTIVE SITE OF TRYPANOSOMAL TRIOSEPHOSPHATE ISOMERASE AS OBSERVED IN THE CRYSTAL STRUCTURES OF THREE DIFFERENT COMPLEXES Classification ISOMERASE(INTRAMOLECULAR OXIDOREDUCTASE) Compound TRIOSEPHOSPHATE ISOMERASE Source Trypanosoma brucei brucei (TPIS_TRYBB) Sequence B:  SKPQPIAAANWKCNGSQQSLSELIDLFNSTSINHDVQCVV ASTFVHLAMTKERLSHPKFVIAAQNAIAKSGAFTGEVSLP ILKDFGVNWIVLGHSERRAYYGETNEIVADKVAAAVASGF MVIACIGETLQERESGRTAVVVLTQIAAIAKKLKKADWAK VVIAYEPVWAIGTGKVATPQQAQEAHALIRSWVSSKIGAD VAGELRILYGGSVNGKNARTLYQQRDVNGFLVGGASLKPE FVDIIKATQ Description Functional site 1) chain B residue 11 type sequence N description BINDING SITE FOR RESIDUE G3P B 300 source : AC1 2) chain B residue 13 type sequence K description BINDING SITE FOR RESIDUE G3P B 300 source : AC1 3) chain B residue 95 type sequence H description BINDING SITE FOR RESIDUE G3P B 300 source : AC1 4) chain B residue 167 type sequence E description BINDING SITE FOR RESIDUE G3P B 300 source : AC1 5) chain B residue 172 type sequence I description BINDING SITE FOR RESIDUE G3P B 300 source : AC1 6) chain B residue 173 type sequence G description BINDING SITE FOR RESIDUE G3P B 300 source : AC1 7) chain B residue 213 type sequence S description BINDING SITE FOR RESIDUE G3P B 300 source : AC1 8) chain B residue 232 type sequence L description BINDING SITE FOR RESIDUE G3P B 300 source : AC1 9) chain B residue 234 type sequence G description BINDING SITE FOR RESIDUE G3P B 300 source : AC1 10) chain B residue 235 type sequence G description BINDING SITE FOR RESIDUE G3P B 300 source : AC1 11) chain B residue 11 type BINDING sequence N description source Swiss-Prot : SWS_FT_FI3 12) chain B residue 13 type BINDING sequence K description source Swiss-Prot : SWS_FT_FI3 13) chain B residue 95 type ACT_SITE sequence H description Electrophile source Swiss-Prot : SWS_FT_FI1 14) chain B residue 167 type ACT_SITE sequence E description Proton acceptor source Swiss-Prot : SWS_FT_FI2

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