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eF-site ID
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6t8v-.AAA.BBB |
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PDB Code
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6t8v |
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Chain
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AAA, BBB |
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click to enlarge
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Title
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Complement factor B in complex with (S)-5,7-Dimethyl-4-((2-phenylpiperidin-1-yl)methyl)-1H-indole |
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Classification
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HYDROLASE |
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Compound
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Complement factor B |
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Source
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(CFAB_HUMAN) |
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Sequence
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AAA: |
SLCGMVWRKGTDYHKQPWQAKISVIRPSKGHESCMGAVVS
EYFVLTAAHCFTVDDKEHSIKVSVGGEKRDLEIEVVLFHP
NYNINGKKEAGIPEFYDYDVALIKLKNKLKYGQTIRPICL
PCTEGTTRALRLPPTTTCQQQKEELLPAQDIKALFVSEEE
KKLTRKEVYIKNGDKKGSCERDAQYAPGYDKVKDISEVVT
PRFLCTGGVSPYADPNTCRGDSGGPLIVHKRSRFIQVGVI
SWGVVDVCKNQKRQKQVPAHARDFHINLFQVLPWLKEKLQ
DEDLGFL
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| BBB: |
SLCGMVWTDYHKQPWQAKISVIRPSKGHESCMGAVVSEYF
VLTAAHCFTVDDKEHSIKVSVGGEKRDLEIEVVLFHPNYN
INGKKEAGIPEFYDYDVALIKLKNKLKYGQTIRPICLPCT
EGTTRALRLPPTTTCQQQKEELLPAQDIKALFVSEEEKKL
TRKEVYIKNGDKKGSCERDAQYAPGYDKVKDISEVVTPRF
LCTGGVSPYADPNTCRGDSGGPLIVHKRSRFIQVGVISWG
VVDVCPAHARDFHINLFQVLPWLKEKLQDEDLGFL
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Description
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Functional site
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|
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1)
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chain |
AAA |
| residue |
57 |
| type |
ACT_SITE |
| sequence |
H
|
| description |
Charge relay system
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| source |
Swiss-Prot : SWS_FT_FI1
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|
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2)
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chain |
AAA |
| residue |
102 |
| type |
ACT_SITE |
| sequence |
D
|
| description |
Charge relay system
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| source |
Swiss-Prot : SWS_FT_FI1
|
|
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3)
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chain |
AAA |
| residue |
195 |
| type |
ACT_SITE |
| sequence |
S
|
| description |
Charge relay system
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| source |
Swiss-Prot : SWS_FT_FI1
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|
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4)
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chain |
BBB |
| residue |
57 |
| type |
ACT_SITE |
| sequence |
H
|
| description |
Charge relay system
|
| source |
Swiss-Prot : SWS_FT_FI1
|
|
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5)
|
chain |
BBB |
| residue |
102 |
| type |
ACT_SITE |
| sequence |
D
|
| description |
Charge relay system
|
| source |
Swiss-Prot : SWS_FT_FI1
|
|
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6)
|
chain |
BBB |
| residue |
195 |
| type |
ACT_SITE |
| sequence |
S
|
| description |
Charge relay system
|
| source |
Swiss-Prot : SWS_FT_FI1
|
|
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7)
|
chain |
AAA |
| residue |
53-58 |
| type |
prosite |
| sequence |
LTAAHC
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| description |
TRYPSIN_HIS Serine proteases, trypsin family, histidine active site. LTAAHC
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| source |
prosite : PS00134
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8)
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chain |
AAA |
| residue |
189-200 |
| type |
prosite |
| sequence |
NTCRGDSGGPLI
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| description |
TRYPSIN_SER Serine proteases, trypsin family, serine active site. NTcrGDSGGPLI
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| source |
prosite : PS00135
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