eF-site ID 6spb-123456CDEFGHIJKLMNOPQRSTUVWXYZ PDB Code 6spb Chain 1, 2, 3, 4, 5, 6, C, D, E, F, G, H, I, J, K, L, M, N, O, P, Q, R, S, T, U, V, W, X, Y, Z click to enlarge Title Pseudomonas aeruginosa 50s ribosome from a clinical isolate with a mutation in uL6 Classification RIBOSOME Compound 23S ribosomal RNA Source ORGANISM_SCIENTIFIC: Pseudomonas aeruginosa; Sequence 1:  KADIHPTYEAIEATCSCGNVIKTRSTLCKPI 2:  AVQQNKKSRSARDMRRSHDALESNALSVEKSTGEVHLRHH VSPDGFYRGRKVV 3:  RELIRLVSSAGTGHFYTTDKNKRTKPEKIEIKKYDPVVRQ HVIYKEAKIK 4:  MKRTFQPSTLKRARVHGFRARMATKNGRQVLSRRRAKGRK RLTV 5:  PKMKTKSGAAKRFKKTAGGLKHKHAFKSHILTKMTTKRKR QLRGTSMLNKSDVARVERSLRLR 6:  MKVRASVKKLCRNCKIIRRDGIVRVICSAEPRHKQRQG C:  IVKCKPTSAGRRFVVKVVNQELHKGAPYAPLLEKKSKSGG RNNNGRITTRHIGGGHKQHYRLVDFRRNKDGIPAIVERVE YDPNRTAHIALLKYADGERRYIIAPKGVAAGDQLISGIGA PIKAGNSMPLRNIPVGSTVHGIELKPGKGAQIARSAGASA QLVAREGAYVTLRLRSGEMRKVLAECRATLGEVSNSEHSL RSLGKAGATRWRGVRPTVRGVAMNPVDHPHGGGEGRTSAG RHPVSPWGLQTKGKKTRSNKRTDNMIVRRRK D:  IGVVGRKCGMTRIFTEEGVSIPVTVIEVEPNRVTQFKTEE TDGYRAVQVTAGERRASRVTKAQAGHFAKANVAAGRGVWE FRLGEEQYAAGDQITVDLFQAGQMVDVTGESKGKGFAGTI KRWNFRGQDNTHGNSVSHRVPGSIGQCQTPGRVFKGKKMS GHLGAERVTVQSLEIVRVDAERNLLLVKGAVPGATGGDVI VRPAAKA E:  QLNVNGAQAIEVSERTFGGEFNETLVHQAVVAYMAGGRQG SKAQKTRSEVSGGGKKPWRQKGTGRARAGTIRSPIWRGGG TTFAAKPRSHEQKLNKKMYRAALRSILAELVRLDRLVVVA DFAVDAPKTKGLVAKLDTLGLKDVLIVTDGVDENLYLAAR NLAHVDVRDVQGSDPVSLIAYDKVLVTVSAVKKFEELLG F:  RLKELYRKEIAPKLKEELQLANVMEVPRVTKITLNMGLGE AVGDKKIIENAVADLEKITGQKPVVTYARKSIAGFKIAAG WPIGVKVTLRSDRMYEFLDRLLSISLPRVRDFRGLNAKSF DGRGNYSMGVKEQIIFPEIDYDKIDALRGLDITLTTTART DDEGRALLRAFKFP G:  SRVAKNPVKLPAGVEIKLAGQQLSIKGAKGALELKVHPSV EVIQDSGELRFAARNGDQQTRAMAGTTRALVNNMVVGVSQ GFERKLQLVGVQAKGQVLSLSLGFSHPVDYELPAGIVAET PSQTDILIKGIDKQLVGQVAAEIRDFRPPEPYKGKGVRYA DEVVRRKEA H:  EVILLEKVANLGNLGDKVNIKGGYARNFLLPQGKATVATA ENVAAFEARRAELEKAAAEKKAAAEARAAQLSELVVTL I:  KKIQAYIKLQVKAGQANPSPPVGPALGQHGVNIMEFCKAF NAKTQGQEPGLPTPVIITVYSDRSFTFETKSTPAAVLLKK AAGITSGSARPNSQKVGTVTRAQLEEIAKTKQADLTAADL DAAVRTIAGSARSMGLNVEG J:  KTYTAKPETVQRDWFVVDAAGQTLGRLATEIARRLRGKHK PEYTPHVDTGDYIVVINAEQVRVTGAKTTDKMYYHHSGFP GGIKSINFEKLIAKAPERVIETAVKGMLPKNPLGRDMYRK LKVYKGASHPHTAQQPQELKI K:  MIQTQSMLDVADNSGARRVMCIKVLGGSHRRYAGIGDIIK VTVKEAIPRGKVKKGQVMTAVVVRTKHGVRRTDGSIIRFD GNAAVLLNNKQEPIGTRIFGPVTRELRTEKFMKIVSLAPE L:  QLNDLRSAPGARREKHRPGRGIGSGLGKTGGRGHKGLTSR SGGKVAPGFEGGQQPLHRRLPKFGFVSLKAMDRAEVRTSE LAKVEGDVVSLQTLKDANLINQHVQRVKVMLSGEVGRAVT LKGIAATKGARAAIEAAGGKFED M:  MLQPKRTKFRKQMTGHNRGLAHRGSKVSFGEYALKATSRG RLTARQIESARRALTRHVKRGGKIWIRVFPDKPVTKKPLE VRMGKGKGGVEYWVAQIQPGKVLYEIEGVSEELAREAFAL AAAKLPLATSFVKRT N:  MRHRKSGRHLSRTSAHRKAMFQNMAVSLFEHELIKTTLPK AKELRRVAEPLITLAKEDSVANRRLAFDRTRSKAAVGKLF NDLGKRYANRPGGYLRILKCGFRAGDNAPMAYVELVDR O:  SVKKETRLRRARKARLKMRELETVRLCVYRSSQHIYAQVI AADGGKVLASASTLDKDLREGATGNIDAAKKVGQLVAERA KAAGVTQVAFDRSGFKYHGRVKALADAAREGGLEF P:  KIIQQIEAEQMNKEIPAFAPGDTVIVQVKVKEGDRQRLQA FEGVVIAKRNRGLNSAFTVRKISNGVGVERTFQTYSPIVD SLSVKRRGDVRKAKLYYLRALSGKAARIKEKLV Q:  ARVKRGVIARRRHKKILKLAKGYYGARSRVFRVAKQAVIK AGQYAYRDRRQRKRQFRALWIARINAGARQNGLSYSRLIA GLKKAAIEIDRKVLADLAVNEKAAFTAIVEKAKASLA R:  MYAVIVTGGKQHKVTEGEFLKVEKLDVATGEAIDFDRVLL VANGEDVKIGLPVVEGAKVTAEVVSHGRHDKVRIIKFRRR KHHMKRQGHRQWFTEIKITGIQ S:  EVAAKLSGARISAQKARLVADQIRGKKVGEALNLLAFSSK KAAEIMKKVLESAVANAEHNEGADVDDLKVSTVFVNEGRS LKRIMPRAKGRADRIVKRSCHITVKVADK T:  AAERVFKVLLGPHISEKATGLADGKSQFVFKVATDATKLE IKKAVESLFSVKVQRVTTLNVKGKTKRTARGLGKRNDWKK AYIALQPGQDLD U:  MQKIRRDDEVIVIAGKDKGKRGKVLKVLADDRLVVGGVNL IKRHTKPNPMLGQQGGIVEKEAPLHVSNVAIFNTETSKAD RVGFKVEDGKKIRVFKSTQKPVQ V:  FIVNAQVRSDLGKGASRRLRRNAGLVPAVVYGGDKEPQSV TLELREIAKLLENEAAFSHVIALNVGGVKETVLIKALQRH PAKGFVMHADFLRVVADHKLTAHVPLHFINEEVAVGVKQA GGEISHTISEVEVSCLPKDLPEFIEVDMAKVELGQIVHLS DLKAPKGVELVQLAHGNDLAVANIHASR W:  TRNGRDSESKRLGVKLFGGQAVKAGNILVRLRGTKFHAGY GVGLGKDHTLFAKVDGVVKFETKGAFGRKYVSIVAA X:  SRVCQVTGKGPVTGNNISHAHNKTRRRFLPNLQHHRFWVE SEKRFVRLRVSAKGMRIIDKRGIEAVLADLRARGEKF Y:  KANELREEKSGPVTGNNISHLLRDQFNLRMQKATGQLGQS HLLSQVKRDIARVKTVLNQQ Z:  ATVKVTLVKSLNGRLANHKACVKGLGLRRINHTVEVQDTP ENRGMINKAYYLLRVEG Description (1)  50S ribosomal protein L2, 50S ribosomal protein L3, 50S ribosomal protein L4, 50S ribosomal protein L5, 50S ribosomal protein L6, 50S ribosomal protein L9, 50S ribosomal protein L11, 50S ribosomal protein L13, 50S ribosomal protein L14, 50S ribosomal protein L15, 50S ribosomal protein L16, 50S ribosomal protein L17, 50S ribosomal protein L18, 50S ribosomal protein L19, 50S ribosomal protein L20, 50S ribosomal protein L21, 50S ribosomal protein L22, 50S ribosomal protein L23, 50S ribosomal protein L24, 50S ribosomal protein L25, 50S ribosomal protein L27, 50S ribosomal protein L28, 50S ribosomal protein L29, 50S ribosomal protein L30, 50S ribosomal protein L31, 50S ribosomal protein L32, 50S ribosomal protein L33, 50S ribosomal protein L34, 50S ribosomal protein L35, 50S ribosomal protein L36/RNA Complex Functional site 1) chain R residue 72-94 type prosite sequence VRIIKFRRRKHHMKRQGHRQWFT description RIBOSOMAL_L21 Ribosomal protein L21 signature. VriiKfrrRKhhmkrqGHRQwfT source prosite : PS01169 2) chain D residue 101-124 type prosite sequence FQAGQMVDVTGESKGKGFAGTIKR description RIBOSOMAL_L3 Ribosomal protein L3 signature. FqagqmvDvtGeSkGKGfaGtikR source prosite : PS00474 3) chain L residue 109-139 type prosite sequence KVMLSGEVGRAVTLKGIAATKGARAAIEAAG description RIBOSOMAL_L15 Ribosomal protein L15 signature. KVMLsGeVgra..VtLkgiaATkgAraaIeaaG source prosite : PS00475 4) chain 5 residue 5-30 type prosite sequence KTKSGAAKRFKKTAGGLKHKHAFKSH description RIBOSOMAL_L35 Ribosomal protein L35 signature. KTKsGAaKRFkktagglkhkhafk..SH source prosite : PS00936 5) chain P residue 87-102 type prosite sequence VKRRGDVRKAKLYYLR description RIBOSOMAL_L19 Ribosomal protein L19 signature. VkRrGDVR.KAKLYYLR source prosite : PS01015 6) chain G residue 150-158 type prosite sequence PEPYKGKGV description RIBOSOMAL_L6_1 Ribosomal protein L6 signature 1. PEpYKGKGV source prosite : PS00525 7) chain C residue 218-229 type prosite sequence PTVRGVAMNPVD description RIBOSOMAL_L2 Ribosomal protein L2 signature. PtvRGVAmNPvD source prosite : PS00467 8) chain J residue 105-127 type prosite sequence VKGMLPKNPLGRDMYRKLKVYKG description RIBOSOMAL_L13 Ribosomal protein L13 signature. VKGMLPknpl.GRdmyrkLkVYkG source prosite : PS00783 9) chain 6 residue 11-37 type prosite sequence CRNCKIIRRDGIVRVICSAEPRHKQRQ description RIBOSOMAL_L36 Ribosomal protein L36 signature. CrnCkiIrRdgiVrViCsaepRHkQrQ source prosite : PS00828 10) chain F residue 57-73 type prosite sequence LEKITGQKPVVTYARKS description RIBOSOMAL_L5 Ribosomal protein L5 signature. LekITGQkpVvTyARkS source prosite : PS00358 11) chain 3 residue 17-36 type prosite sequence YTTDKNKRTKPEKIEIKKYD description RIBOSOMAL_L33 Ribosomal protein L33 signature. YtTdKNkrtkPekIEikKYD source prosite : PS00582 12) chain H residue 13-40 type prosite sequence GNLGDKVNIKGGYARNFLLPQGKATVAT description RIBOSOMAL_L9 Ribosomal protein L9 signature. GnlGdkvnIkgGYarNFLlpqgkAtvaT source prosite : PS00651 13) chain Y residue 39-53 type prosite sequence QSHLLSQVKRDIARV description RIBOSOMAL_L29 Ribosomal protein L29 signature. QSHLLSqVKRDIARV source prosite : PS00579 14) chain U residue 7-24 type prosite sequence DDEVIVIAGKDKGKRGKV description RIBOSOMAL_L24 Ribosomal protein L24 signature. DDeViVIaGkdKGkr.GkV source prosite : PS01108 15) chain S residue 83-107 type prosite sequence KRIMPRAKGRADRIVKRSCHITVKV description RIBOSOMAL_L22 Ribosomal protein L22 signature. KriMpRAkGRadrivkrsCHITVkV source prosite : PS00464 16) chain M residue 59-70 type prosite sequence KRGGKIWIRVFP description RIBOSOMAL_L16_1 Ribosomal protein L16 signature 1. KRgGKIWIRVFP source prosite : PS00586 17) chain M residue 82-93 type prosite sequence RMGKGKGGVEYW description RIBOSOMAL_L16_2 Ribosomal protein L16 signature 2. RMGkGKGgveyW source prosite : PS00701 18) chain I residue 127-142 type prosite sequence RTIAGSARSMGLNVEG description RIBOSOMAL_L11 Ribosomal protein L11 signature. RtIaGSarSMGlNVeG source prosite : PS00359 19) chain N residue 34-56 type prosite sequence IKTTLPKAKELRRVAEPLITLAK description RIBOSOMAL_L17 Ribosomal protein L17 signature. IkTTlpKaKelrrvaEpLITlAK source prosite : PS01167 20) chain 4 residue 2-21 type prosite sequence KRTFQPSTLKRARVHGFRAR description RIBOSOMAL_L34 Ribosomal protein L34 signature. KRTFQpstlkRarvh.GFraR source prosite : PS00784 21) chain Q residue 54-70 type prosite sequence KRQFRALWIARINAGAR description RIBOSOMAL_L20 Ribosomal protein L20 signature. KrqfRaLWIARINagaR source prosite : PS00937 22) chain K residue 60-86 type prosite sequence AVVVRTKHGVRRTDGSIIRFDGNAAVL description RIBOSOMAL_L14 Ribosomal protein L14 signature. AVVVrtkhgvrrt.DGsiirFdgNaaVL source prosite : PS00049

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