eF-site ID 6skl-6 PDB Code 6skl Chain 6 click to enlarge Title Cryo-EM structure of the CMG Fork Protection Complex at a replication fork - Conformation 1 Classification REPLICATION Compound DNA replication licensing factor MCM2 Source (CSM3_YEAST) Sequence 6:  SFKSRALNHVKKVDDVTGEKVREAFEQFLEDFSVQSTDTG EVEKVYRAQIEFMKIYDLNTIYIDYQHLSMRENGALAMAI SEQYYRFLPFLQKGLRRVVRKYAPELLNTSSPEQTERVFQ ISFFNLPTVHRIRDIRSEKIGSLLSISGTVTRTSEVRPEL YKASFTCDMCRAIVDNVEQSFKYTEPTFCPNPSCENRAFW TLNVTRSRFLDWQKVRIQENANEIPTGSMPRTLDVILRGD SVERAKPGDRCKFTGVEIVVPDVTQLGLPGVKPSSNSGVT GLRSLGVRDLTYKISFLACHVISIGNERDQEVFLNSLSSD EINELKEMVKDEHIYDKLVRSIAPAVFGHEAVKKGILLQM LGGVHKSTVEGIKLRGDINICVVGDPSTSKSQFLKYVVGF APRSVYTSGKASSAAGLTAAVVRDDYTIEAGALMLADNGI CCIDEFDKMDISDQVAIHEAMEQQTISIAKAGIHATLNAR TSILAAANPVGGRYNRKLSLRGNLNMTAPIMSRFDLFFVI LDDCNEKIDTELASHIVDLHMKPPFSAEQLRRYIKYARTF KPILTKEARSYLVEKYKELRKDDAQGFSRSSYRITVRQLE SMIRLSEAIARANCVDEITPSFIAEAYDLLRQSIIRV Description Functional site 1) chain 6 residue 657 type sequence E description binding site for residue ANP 2 902 source : AC2 2) chain 6 residue 658 type sequence Q description binding site for residue ANP 2 902 source : AC2 3) chain 6 residue 708 type sequence R description binding site for residue ANP 2 902 source : AC2 4) chain 6 residue 797 type sequence V description binding site for residue ANP 2 902 source : AC2 5) chain 6 residue 798 type sequence R description binding site for residue ANP 2 902 source : AC2 6) chain 6 residue 801 type sequence E description binding site for residue ANP 2 902 source : AC2 7) chain 6 residue 311 type sequence C description binding site for residue ZN 6 1400 source : AD1 8) chain 6 residue 314 type sequence C description binding site for residue ZN 6 1400 source : AD1 9) chain 6 residue 333 type sequence C description binding site for residue ZN 6 1400 source : AD1 10) chain 6 residue 338 type sequence C description binding site for residue ZN 6 1400 source : AD1 11) chain 6 residue 634-642 type prosite sequence GICCIDEFD description MCM_1 MCM family signature. GVCCIDEFD source prosite : PS00847

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