eF-site ID 6skl-5 PDB Code 6skl Chain 5 click to enlarge Title Cryo-EM structure of the CMG Fork Protection Complex at a replication fork - Conformation 1 Classification REPLICATION Compound DNA replication licensing factor MCM2 Source (CSM3_YEAST) Sequence 5:  NDDDNTEIIKSFKNFILEFRLDSQFIYRDQLRNNILVKNY SLTVNMEHLIGYNEDIYKKLSDEPSDIIPLFETAITQVAK RISILSRASLPTFQLILNSNANQIPLRDLDSEHVSKIVRL SGIIISTSVLSSRATYLSIMCRNCRHTTSITINNFNVSLP RSCLSNCGPDPYIIIHESSKFIDQQFLKLQEIPELVPVGE MPRNLTMTCDRYLTNKVIPGTRVTIVGIYSIYNSKNGVAI RTPYIKILGIQSDVETSSIWNSVTMFTEEEEEEFLQLSRN PKLYEILTNSIAPSIFGNEDIKKAIVCLLMGGSKKILPDG MRLRGDINVLLLGDPGTAKSQLLKFVEKVSPIAVYTSGKG SSAAGLTASVQRDPMTREFYLEGGAMVLADGGVVCIDEFD KMRDEDRVAIHEAMEQQTISIAKAGITTVLNSRTSVLAAA NPIYGRYDDLKSPGDNIDFQTTILSRFDMIFIVKDDHNEE RDISIANHVINIHTGNANAMQNQQEENGSEISIEKMKRYI TYCRLKCAPRLSPQAAEKLSSNFVTIRKQLLINELESTER SSIPITIRQLEAIIRITESLAKLELSPIAQERHVDEAIRL FQASTMDAASQ Description (1)  Cell division control protein 45, DNA polymerase alpha-binding protein, DNA replication complex GINS protein PSF1, DNA replication complex GINS protein PSF2, DNA replication complex GINS protein SLD5, DNA replication licensing factor MCM2, DNA replication licensing factor MCM3, Minichromosome maintenance protein 5, DNA replication licensing factor MCM6, DNA replication licensing factor MCM4, DNA replication licensing factor MCM7, DNA replication complex GINS protein PSF3, Topoisomerase 1-associated factor 1, Chromosome segregation in meiosis protein 3/DNA Complex Functional site 1) chain 5 residue 498 type sequence E description binding site for residue ANP 3 1500 source : AC4 2) chain 5 residue 499 type sequence Q description binding site for residue ANP 3 1500 source : AC4 3) chain 5 residue 549 type sequence R description binding site for residue ANP 3 1500 source : AC4 4) chain 5 residue 650 type sequence I description binding site for residue ANP 3 1500 source : AC4 5) chain 5 residue 651 type sequence R description binding site for residue ANP 3 1500 source : AC4 6) chain 5 residue 654 type sequence E description binding site for residue ANP 3 1500 source : AC4 7) chain 5 residue 377 type sequence S description binding site for residue ANP 5 801 source : AC7 8) chain 5 residue 379 type sequence F description binding site for residue ANP 5 801 source : AC7 9) chain 5 residue 418 type sequence P description binding site for residue ANP 5 801 source : AC7 10) chain 5 residue 419 type sequence G description binding site for residue ANP 5 801 source : AC7 11) chain 5 residue 420 type sequence T description binding site for residue ANP 5 801 source : AC7 12) chain 5 residue 421 type sequence A description binding site for residue ANP 5 801 source : AC7 13) chain 5 residue 422 type sequence K description binding site for residue ANP 5 801 source : AC7 14) chain 5 residue 423 type sequence S description binding site for residue ANP 5 801 source : AC7 15) chain 5 residue 424 type sequence Q description binding site for residue ANP 5 801 source : AC7 16) chain 5 residue 524 type sequence N description binding site for residue ANP 5 801 source : AC7 17) chain 5 residue 423 type sequence S description binding site for residue MG 5 802 source : AC8 18) chain 5 residue 183 type sequence C description binding site for residue ZN 5 803 source : AC9 19) chain 5 residue 186 type sequence C description binding site for residue ZN 5 803 source : AC9 20) chain 5 residue 211 type sequence C description binding site for residue ZN 5 803 source : AC9 21) chain 5 residue 236 type sequence C description binding site for residue ZN 5 803 source : AC9 22) chain 5 residue 475-483 type prosite sequence GVVCIDEFD description MCM_1 MCM family signature. GVVCIDEFD source prosite : PS00847

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