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eF-site ID
|
6skl-4 |
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PDB Code
|
6skl |
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Chain
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4 |
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click to enlarge
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Title
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Cryo-EM structure of the CMG Fork Protection Complex at a replication fork - Conformation 1 |
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Classification
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REPLICATION |
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Compound
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DNA replication licensing factor MCM2 |
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Source
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(CSM3_YEAST) |
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Sequence
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4: |
SEPLRIIWGTNVSIQECTTNFRNFLMSFKYKFRKILDERE
EFINNTTDEELYYIKQLNEMRELGTSNLNLDARNLLAYKQ
TEDLYHQLLNYPQEVISIMDQTIKDCMVSLIVDNNLDYDL
DEIETKFYKVRPYNVGSCKGMRELNPNDIDKLINLKGLVL
RSTPVIPDMKVAFFKCNVCDHTMAVEIDRGVIQEPARCER
IDCNEPNSMSLIHNRCSFADKQVIKLQETPDFVPDGQTPH
SISLCVYDELVDSCRAGDRIEVTGTFRSIPIRANSRQRVL
KSLYKTYVDVVHVKKVDLAKIREVAAREDLYSLLARSIAP
SIYELEDVKKGILLQLFGGTNKTFRYRGDINILLCGDPST
SKSQILQYVHKITPRGVYTSGKGSSAVGLTAYITRVLESG
ALVLSDGGVCCIDEFDKMSDSTRSVLHEVMEQQTISIAKA
GIITTLNARSSILASANPIGSRYNPNLPVTENIDLPPPLL
SRFDLVYLVLDKVDEKNDRELAKHLTNLYLEDVLPVEFLT
MYISYAKEHIHPIITEAAKTELVRAYVGMRKMTATTRQLE
SMIRLAEAHAKMKLKNVVELEDVQEAVRLIRSAIKDKIDM
NLVQTGKSVIQRKLQEDLSREIMNVLKDQASDSMSFNELI
KQINEHSQDRVESSDIQEALSRLQQEDKVIVLGGVRRSV
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Description
|
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Functional site
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|
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1)
|
chain |
4 |
| residue |
349 |
| type |
|
| sequence |
C
|
| description |
binding site for residue ZN 4 1400
|
| source |
: AC6
|
|
|
2)
|
chain |
4 |
| residue |
352 |
| type |
|
| sequence |
C
|
| description |
binding site for residue ZN 4 1400
|
| source |
: AC6
|
|
|
3)
|
chain |
4 |
| residue |
371 |
| type |
|
| sequence |
C
|
| description |
binding site for residue ZN 4 1400
|
| source |
: AC6
|
|
|
4)
|
chain |
4 |
| residue |
376 |
| type |
|
| sequence |
C
|
| description |
binding site for residue ZN 4 1400
|
| source |
: AC6
|
|
|
5)
|
chain |
4 |
| residue |
627-635 |
| type |
prosite |
| sequence |
GVCCIDEFD
|
| description |
MCM_1 MCM family signature. GVCCIDEFD
|
| source |
prosite : PS00847
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