eF-site ID 6skl-3 PDB Code 6skl Chain 3 click to enlarge Title Cryo-EM structure of the CMG Fork Protection Complex at a replication fork - Conformation 1 Classification REPLICATION Compound DNA replication licensing factor MCM2 Source (CSM3_YEAST) Sequence 3:  DAVFGDRVRRFQEFLDTFTSYRDSVRSIQVYNSNNAANYN ILPHRIIISLDDLREFDRSFWSGILVEPAYFIPPAEKALT DLADSMDDVPHPNASAVSSRHPWKLSFKGSFGAHALSPRT LTAQHLNKLVSVEGIVTKTSLVRPKLIRSVHYAAKTGRFH YRDYTDATTTLTTRIPTPAIYPTEDTEGNKLTTEYGYSTF IDHQRITVQEMPEMAPAGQLPRSIDVILDDDLVDKTKPGD RVNVVGVFKSLGAGGMNQSNSNTLIGFKTLILGNTVYPLH ARAARQMLTDFDIRNINKLSKKKDIFDILSQSLAPSIYGH DHIKKAILLMLMGGVEKNLENGSHLRGDINILMVGDPSTA KSQLLRFVLNTASLAIATTGRGSSGVGLTAAVTTDRETGE RRLEAGAMVLADRGVVCIDEFDKMTDVDRVAIHEVMEQQT VTIAKAGIHTTLNARCSVIAAANPVFGQYDVNRDPHQNIA LPDSLLSRFDLLFVVTDDINEIRDRSISEHVLRTHRYLPP GYLEGEPVRPKLVTIPFLRKYVQYAKERVIPQLTQEAINV IVKNYTDLRNDPITARTLETLIRLATAHAKVRLSKTVNKV DAKVAANLLRFALLGE Description (1)  Cell division control protein 45, DNA polymerase alpha-binding protein, DNA replication complex GINS protein PSF1, DNA replication complex GINS protein PSF2, DNA replication complex GINS protein SLD5, DNA replication licensing factor MCM2, DNA replication licensing factor MCM3, Minichromosome maintenance protein 5, DNA replication licensing factor MCM6, DNA replication licensing factor MCM4, DNA replication licensing factor MCM7, DNA replication complex GINS protein PSF3, Topoisomerase 1-associated factor 1, Chromosome segregation in meiosis protein 3/DNA Complex Functional site 1) chain 3 residue 372 type sequence Y description binding site for residue ANP 3 1500 source : AC4 2) chain 3 residue 411 type sequence P description binding site for residue ANP 3 1500 source : AC4 3) chain 3 residue 412 type sequence S description binding site for residue ANP 3 1500 source : AC4 4) chain 3 residue 413 type sequence T description binding site for residue ANP 3 1500 source : AC4 5) chain 3 residue 414 type sequence A description binding site for residue ANP 3 1500 source : AC4 6) chain 3 residue 415 type sequence K description binding site for residue ANP 3 1500 source : AC4 7) chain 3 residue 416 type sequence S description binding site for residue ANP 3 1500 source : AC4 8) chain 3 residue 417 type sequence Q description binding site for residue ANP 3 1500 source : AC4 9) chain 3 residue 517 type sequence N description binding site for residue ANP 3 1500 source : AC4 10) chain 3 residue 565 type sequence V description binding site for residue ANP 3 1500 source : AC4 11) chain 3 residue 416 type sequence S description binding site for residue MG 3 1501 source : AC5 12) chain 3 residue 468-476 type prosite sequence GVVCIDEFD description MCM_1 MCM family signature. GVVCIDEFD source prosite : PS00847

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