eF-site ID 6skl-2 PDB Code 6skl Chain 2 click to enlarge Title Cryo-EM structure of the CMG Fork Protection Complex at a replication fork - Conformation 1 Classification REPLICATION Compound DNA replication licensing factor MCM2 Source (CSM3_YEAST) Sequence 2:  DIDPLREELTLESLSNVKANSYSEWITQPNVSRTIARELK SFLLEYTDETGRSVYGARIRTLGEMNSESLEVNYRHLAES KAILALFLAKCPEEMLKIFDLVAMEATELHYPDYARIHSE IHVRISDFPTIYSLRELRESNLSSLVRVTGVVTRRTGVFP QLKYVKFNCLKCGSILGPFFQDSNEEIRISFCTNCKSKGP FRVNGEKTVYRNYQRVTLQEAPGTVPPGRLPRHREVILLA DLVDVSKPGEEVEVTGIYKNNYDGNLNAKNGFPVFATIIE ANSIKRREGNTANEGEEGLDVFSWTEEEEREFRKISRDRG IIDKIISSMAPSIYGHRDIKTAVACSLFGGVPKNVNGKHS IRGDINVLLLGDPGTAKSQILKYVEKTAHRAVFATGQGAS AVGLTASVRKDPITKEWTLEGGALVLADKGVCLIDEFDKM NDQDRTSIHEAMEQQSISISKAGIVTTLQARCSIIAAANP NGGRYNSTLPLAQNVSLTEPILSRFDILCVVRDLVDEEAD ERLATFVVDSHVRSHPENLNARQRRLQRQRKKEEEISPIP QELLMKYIHYARTKIYPKLHQMDMDKVSRVYADLRRESIS TGSFPITVRHLESILRIAESFAKMRLSEFVSSYDLDRAIK VVVDSFVDAQKVSVRRQLRRSFAIYTLGH Description (1)  Cell division control protein 45, DNA polymerase alpha-binding protein, DNA replication complex GINS protein PSF1, DNA replication complex GINS protein PSF2, DNA replication complex GINS protein SLD5, DNA replication licensing factor MCM2, DNA replication licensing factor MCM3, Minichromosome maintenance protein 5, DNA replication licensing factor MCM6, DNA replication licensing factor MCM4, DNA replication licensing factor MCM7, DNA replication complex GINS protein PSF3, Topoisomerase 1-associated factor 1, Chromosome segregation in meiosis protein 3/DNA Complex Functional site 1) chain 2 residue 341 type sequence C description binding site for residue ZN 2 901 source : AC1 2) chain 2 residue 344 type sequence C description binding site for residue ZN 2 901 source : AC1 3) chain 2 residue 364 type sequence C description binding site for residue ZN 2 901 source : AC1 4) chain 2 residue 367 type sequence C description binding site for residue ZN 2 901 source : AC1 5) chain 2 residue 506 type sequence Y description binding site for residue ANP 2 902 source : AC2 6) chain 2 residue 508 type sequence H description binding site for residue ANP 2 902 source : AC2 7) chain 2 residue 545 type sequence P description binding site for residue ANP 2 902 source : AC2 8) chain 2 residue 546 type sequence G description binding site for residue ANP 2 902 source : AC2 9) chain 2 residue 547 type sequence T description binding site for residue ANP 2 902 source : AC2 10) chain 2 residue 548 type sequence A description binding site for residue ANP 2 902 source : AC2 11) chain 2 residue 549 type sequence K description binding site for residue ANP 2 902 source : AC2 12) chain 2 residue 550 type sequence S description binding site for residue ANP 2 902 source : AC2 13) chain 2 residue 551 type sequence Q description binding site for residue ANP 2 902 source : AC2 14) chain 2 residue 651 type sequence N description binding site for residue ANP 2 902 source : AC2 15) chain 2 residue 695 type sequence L description binding site for residue ANP 2 902 source : AC2 16) chain 2 residue 699 type sequence V description binding site for residue ANP 2 902 source : AC2 17) chain 2 residue 550 type sequence S description binding site for residue MG 2 903 source : AC3 18) chain 2 residue 531 type sequence H description binding site for residue ANP 5 801 source : AC7 19) chain 2 residue 625 type sequence E description binding site for residue ANP 5 801 source : AC7 20) chain 2 residue 626 type sequence Q description binding site for residue ANP 5 801 source : AC7 21) chain 2 residue 676 type sequence R description binding site for residue ANP 5 801 source : AC7 22) chain 2 residue 807 type sequence V description binding site for residue ANP 5 801 source : AC7 23) chain 2 residue 808 type sequence R description binding site for residue ANP 5 801 source : AC7 24) chain 2 residue 811 type sequence E description binding site for residue ANP 5 801 source : AC7 25) chain 2 residue 676 type sequence R description binding site for residue MG 5 802 source : AC8 26) chain 2 residue 602-610 type prosite sequence GVCLIDEFD description MCM_1 MCM family signature. GVVCIDEFD source prosite : PS00847

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