eF-site ID 6s12-1234ABCDEFGHIJKLMNOPQRSTUVWXYZ PDB Code 6s12 Chain 1, 2, 3, 4, A, B, C, D, E, F, G, H, I, J, K, L, M, N, O, P, Q, R, S, T, U, V, W, X, Y, Z Title Erythromycin Resistant Staphylococcus aureus 50S ribosome (delta R88 A89 uL22). Classification RIBOSOME Compound 23S ribosomal RNA Source ORGANISM_SCIENTIFIC: Staphylococcus aureus; Sequence 1:  RVNVTLACTECGDRNYITTKNKRNNPERIEMKKYCPRLNK YTLHRET 2:  VKRTYQPNKRKHSKVHGFRKRMSTKNGRKVLARRRRKGRK VLS 3:  PKMKTHRGAAKRVKRTASGQLKRSRAFTSHLFANKSTKQK RQLRKARLVSKSDMKRVKQLLAYK 4:  MKVRPSVKPICEKCKVIKRKGKVMVICENPKHKQRQG A:  UUAAGUUAUUAAGGGCGCACGGUGGAUGCCUUGGCACUAG AAGCCGAUGAAGGACGUUACUAACGACGAUAUGCUUUGGG GAGCUGUAAGUAAGCUUUGAUCCAGAGAUUUCCGAAUGGG GAAACCCAGCAUGAGUUAUGUCAUGUUAUCGAUAUGUGAA UACAUAGCAUAUCAGAAGGCACACCCGGAGAACUGAAACA UCUUAGUACCCGGAGGAAGAGAAAGAAAAUUCGAUUCCCU UAGUAGCGGCGAGCGAAAUGGGAAGAGCCCAAACCAACAA GCUUGCUUGUUGGGGUUGUAGGACACUCUACGGAGUUACA AAGGACGACAUUAGACGAAUCAUCUGGAAAGAUGAAUCAA AGAAGGUAAUAAUCCUGUAGUCGAAAAUGUUGUCUCUCUU GAGUGGAUCCUGAGUACGACGGAGCACGUGAAAUUCCGUC GGAAUCUGGGAGGACCAUCUCCUAAGGCUAAAUACUCUCU AGUGACCGAUAGUGAACCAGUACCGUGAGGGAAAGGUGAA AAGCACCCCGGAAGGGGAGUGAAAUAGAACCUGAAACCGU GUGCUUACAAGUAGUCAGAGCCCGUUAAUGGGUGAUGGCG UGCCUUUUGUAGAAUGAACCGGCGAGUUACGAUUUGAUGC AAGGUUAAGCAGUAAAUGUGGAGCCGUAGCGAAAGCGAGU CUGAAUAGGGCGUUUAGUAUUUGGUCGUAGACCCGAAACC AGGUGAUCUACCCUUGGUCAGGUUGAAGUUCAGGUAACAC UGAAUGGAGGACCGAACCGACUUACGUUGAAAAGUGAGCG GAUGAACUGAGGGUAGCGGAGAAAUUCCAAUCGAACCUGG AGAUAGCUGGUUCUCUCCGAAAUAGCUUUAGGGCUAGCCU CAAGUGAUGAUUAUUGGAGGUAGAGCACUGUUUGGACGAG GGGCCGGUUACCGAAUUCAGACAAACUCCGAAUGCCAAUU AAUUUAACUUGGGAGUCAGAACAUGGGUGAUAAGGUCCGU GUUCGAAAGGGAAACAGCCCAGACCACCAGCUAAGGUCCC AAAAUAUAUGUUAAGUGGAAAAGGAUGUGGCGUUGCCCAG ACAACUAGGAUGUUGGCUUAGAAGCAGCCAUCAUUUAAAG AGUGCGUAAUAGCUCACUAGUCGAGUGACACUGCGCCGAA AAUGUACCGGGGCUAAACAUAUUACCGAAGCUGUGGAUUG UCCUUUGGACAAUGGUAGGAGAGCGUUCUAAGGGCGUUGA AGCAUGAUCGUAAGGACAUGUGGAGCGCUUAGAAGUGAGA AUGCCGGUGUGAGUAGCGAAAGACGGGUGAGAAUCCCGUC CACCGAUUGACUAAGGUUUCCAGAGGAAGGCUCGUCCGCU CUGGGUUAGUCGGGUCCUAAGCUGAGGCCGACAGGCGUAG GCGAUGGAUAACAGGUUGAUAUUCCUGUACCACCUAUAAU CGUUUUAAUCGAUGGGGGGACGCAGUAGGAUAGGCGAAGC GUGCGAUUGGAUUGCACGUCUAAGCAGUAAGGCUGAGUAU UAGGCAAAUCCGGUACUCGUUAAGGCUGAGCUGUGAUGGG GAGAAGACAUUGUGUCUUCGAGUCGUUGAUUUCACACUGC CGAGAAAAGCCUCUAGAUAGAAAAUAGGUGCCCGUACCGC AAACCGACACAGGUAGUCAAGAUGAGAAUUCUAAGGUGAG CGAGCGAACUCUCGUUAAGGAACUCGGCAAAAUGACCCCG UAACUUCGGGAGAAGGGGUGCUCUUUAGGGUUAACGCCCA GAAGAGCCGCAGUGAAUAGGCCCAAGCGACUGUUUAUCAA AAACACAGGUCUCUGCUAAACCGUAAGGUGAUGUAUAGGG GCUGACGCCUGCCCGGUGCUGGAAGGUUAAGAGGAGUGGU UAGCUUCUGCGAAGCUACGAAUCGAAGCCCCAGUAAACGG CGGCCGUAUAACGGUCCUAAGGUAGCGAAAUUCCUUGUCG GGUAAGUUCCGACCCGCACGAAAGGCGUAACGAUUUGGGC ACUGUCUCAACGAGAGACUCGGUGAAAUCAUAGUACCUGU GAAGAUGCAGGUUACCCGCGACAGGACGGAAAGACCCCGU GGAGCUUUACUGUAGCCUGAUAUUGAAAUUCGGCACAGCU UGUACAGGAUAGGUAGGAGCCUUUGAAACGUGAGCGCUAG CUUACGUGGAGGCGCUGGUGGGAUACUACCCUAGCUGUGU UGGCUUUCUAACCCGCACCACUUAUCGUGGUGGGAGACAG UGUCAGGCGGGCAGUUUGACUGGGGCGGUCGCCUCCUAAA AGGUAACGGAGGCGCUCAAAGGUUCCCUCAGAAUGGUUGG AAAUCAUUCAUAGAGUGUAAAGGCAUAAGGGAGCUUGACU GCGAGACCUACAAGUCGAGCAGGGUCGAAAGACGGACUUA GUGAUCCGGUGGUUCCGCAUGGAAGGGCCAUCGCUCAACG GAUAAAAGCUACCCCGGGGAUAACAGGCUUAUCUCCCCCA AGAGUUCACAUCGACGGGGAGGUUUGGCACCUCGAUGUCG GCUCAUCGCAUCCUGGGGCUGUAGUCGGUCCCAAGGGUUG GGCUGUUCGCCCAUUAAAGCGGUACGCGAGCUGGGUUCAG AACGUCGUGAGACAGUUCGGUCCCUAUCCGUCGUGGGCGU AGGAAAUUUGAGAGGAGCUGUCCUUAGUACGAGAGGACCG GGAUGGACAUACCUCUGGUGUACCAGUUGUCGUGCCAACG GCAUAGCUGGGUAGCUAUGUGUGGACGGGAUAAGUGCUGA AAGCAUCUAAGCAUGAAGCCCCCCUCAAGAUGAGAUUUCC CAACUUCGGUUAUAAGAUCCCUCAAAGAUGAUGAGGUUAA UAGGUUCGAGGUGGAAGCAUGGUGACAUGUGGAGCUGACG AAUACUAAUCGAUCGAAGACUUAAU B:  UCUGGUGACUAUAGCAAGGAGGUCACACCUGUUCCCAUGC CGAACACAGAAGUUAAGCUCCUUAGCGUCGAUGGUAGUCG AACUUACGUUCCGCUAGAGUAGAACGUUGCCAGGC C:  AIKKYKPITNGRRNMTSLDFAEITKTTPEKSLLKPLPKKA GRNNQGKLTVRHHGGGHKRQYRVIDFKRNKDGINAKVDSI QYDPNRSANIALVVYADGEKRYIIAPKGLEVGQIVESGAE ADIKVGNALPLQNIPVGTVVHNIELKPGKGGQIARSAGAS AQVLGKEGKYVLIRLRSGEVRMILSTCRATIGQVGNLQHE LVNVGKAGRSRWKGIRPTVRGSVMNPNDHPHGGGEGRAPI GRPSPMSPWGKPTLGKKTRRGKKSSDKLIVRGRK D:  TKGILGRKIGMTQVFGENGELIPVTVVEAKENVVLQKKTV EVDGYNAIQVGFEDKKAYKKDAKSNKYANKPAEGHAKKAD AAPKRFIREFRNVDVDAYEVGQEVSVDTFVAGDVIDVTGV SKGKGFQGAIKRHGQSRGPMSHGSHFHRAPGSVGMASDAS RVFKGQKMPGRMGGNTVTVQNLEVVQVDTENKVILVKGNV PGPKKGLVEIRTSIK E:  ANYDVLKLDGTKSGSIELSDAVFGIEPNNSVLFEAINLQR ASLRQGTHAVKNRSAVSGGGRKPWKQKGTGRARQGTIRAP QWRGGGIVFGPTPRSYAYKMPKKMRRLALRSALSFKAQEN GLTVVDAFNFEAPKTKEFKNVLSTLEQPKKVLVVTENEDV NVELSARNIPGVQVTTAQGLNVLDITNADSLVITEAAAKK VEEVLG F:  NRLKEKFNTEVTENLMKKFNYSSVMEVPKIDKIVVNMGVG DAVQNSKVLDNAVEELELITGQKPLVTKAKKSIATFRLRE GMPIGAKVTLRGERMYEFLDKLISVSLPRVRDFQGVSKKA FDGRGNYTLGVKEQLIFPEIDYDKVSKVRGMDIVIVTTAN TDEEARELLANFGMP G:  SRVGKKIIDIPSDVTVTFDGNHVTVKGPKGELSRTLNERM TFKQEENTIEVVRPSDSKEDRTNHGTTRALLNNMVQGVSQ GYVKVLELVGVGYRAQMQGKDLILNVGYSHPVEIKAEENI TFSVEKNTVVKVEGISKEQVGALASNIRSVRPPEPYKGKG IRYQGEYVRRKEGKT H:  MRQTFMANESNIERKWYVIDAEGQTLGRLSSEVASILRGK NKVTYTPHVDTGDYVIVINASKIEFTGNKETDKVYYRHSN HPGGIKSITAGELRRTNPERLIENSIKGMLPSTRLGEKQG KKLFVYGGAEHPHAAQQPENYELRG I:  MIQQETRLKVADNSGAREVLTIKVLGGSGRKTANIGDVIV CTVKNATPGGVVKKGDVVKAVIVRTKSGVRRNDGSYIKFD ENACVIIRDDKGPRGTRIFGPVARELREGNFMKIVSLAPE VL J:  MKLHELKPAEGSRKERNRVGRGVATGNGKTSGRGHKGQKA RSGGGVRPGFEGGQLPLFRRLPKRGFTNINRKEYAIVNLD QLNKFEDGTEVTPALLVESGVVKNEKSGIKILGNGSLDKK LTVKAHKFSASAAEAIDAKGGAHEVI K:  MLLPKRVKYRRQHRPKTTGRSKGGNYVTFGEFGLQATTTS WITSRQIESARIAMTRYMKRGGKVWIKIFPHTPYTKKPLE VRMGAGKGAVEGWIAVVKPGRILFEVAGVSEEVAREALRL ASHKLPVKTKFVKREEL L:  YRKLGRTSDQRKAMLRDLATSLIISERIETTEARAKEVRS VVEKLITLGKKGDLASRRNAAKTLRNVEILNEDETTQTAL QKLFGEIAERYTERQGGYTRILKQGPRRGDGAESVIIELV M:  MISKIDKNKVRLKRHARVRTNLSGTAEKPRLNVYRSNKHI YAQIIDDNKGVTLAQASSKDSDIATTATKVELATKVGEAI AKKAADKGIKEIVFDRGGYLYHGRVKALAEAARESGLEF N:  TNHKLIEAVTKSQLRTDLPSFRPGDTLRVHVRIIEGTRER IQVFEGVVIKRRGGGVSETFTVRKISSGVGVERTFPLHTP KIEKIEVKRRGKVRRAKLYYLRSLRGKAARIQEI O:  PRVKGGTVTRARRKKTIKLAKGYFGSKHTLYKVAKQQVMK SGQYAFRDRRQRKRDFRKLWITRINAAARQHEMSYSRLMN GLKKAGIDINRKMLSEIAISDEKAFAQLVTKAKDAL P:  MFAIIETGGKQIKVEEGQEIFVEKLDVNEGDTFTFDKVLF VGGDSVKVGAPTVEGATVTATVNKQGRGKKITVFTYKRRK NSKRKKGHRQPYTKLTIDKINA Q:  MEAKAVARTIRIAPRKVRLVLDLIRGKNAAEAIAILKLTN KASSPVIEKVLMSALANAEHNYDMNTDELVVKEAYANEGP TLKRFRPQGRASAINKRTSHITIVVSDGKE R:  EARDILKRPVITEKSSEAMAEDKYTFDVDTRVNKTQVKMA VEEIFNVKVASVNIMNYKPKKKRMGRYQGYTNKRRKAIVT LKEGSIDLF S:  HIKKGDNVKVIAGKDKGKEGKVIATLPKKDRVVVEGVNIM KKHQKPTQLNPEGGILETEAAIHVSNVQLLDPKTNEPTRV GYKFVDGKKVRIAKKSGEEIKSN T:  ASLKSIIRQGKQTRSDLKQLRKSGKVPAVVYGYGTKNVSV KVDEVEFIKVIREVGRNGVIELGVGSKTIKVMVADYQFDP LKNQITHIDFLAIN U:  KKGVSSTKNGRDSESKRLGAKRADGQFVTGGSILYRQRGT KIYPGENVGRGGDDTLFAKIDGVVKFERKGRDKKQVSVYA VA V:  KQCFVTGRKASTGNRRSHALNSTKRRWNANLQKVRILVDG KPKKVWVSARALKSGKVT W:  KAKEIRDLTTSEIEEQIKSSKEELFNLRFQLATGQLEETA RIRTVRKTIARLKTVAREREIEQSKAN X:  AKLQITLTRSVIGRPETQRKTVEALGLKKTNSSVVVEDNP AIRGQINKVKHLVTVEEK Y:  MKQGIHPEYHQVIFLDTTTNFKFLSGSTKTSSEMMEWEDG KEYPVIRLDISSDSHPFYT Z:  AVPKRRTSKTRKNKRRTHFKISVPGMTECPNCGEYKLSHR VCKNCGSY Description (1)  50S ribosomal protein L2, 50S ribosomal protein L3, 50S ribosomal protein L4, 50S ribosomal protein L5, 50S ribosomal protein L6, 50S ribosomal protein L13, 50S ribosomal protein L14, 50S ribosomal protein L15, 50S ribosomal protein L16, 50S ribosomal protein L17, 50S ribosomal protein L18, 50S ribosomal protein L19, 50S ribosomal protein L20, 50S ribosomal protein L21, 50S ribosomal protein L22, 50S ribosomal protein L23, 50S ribosomal protein L24, 50S ribosomal protein L25, 50S ribosomal protein L27, 50S ribosomal protein L28, 50S ribosomal protein L29, 50S ribosomal protein L30, 50S ribosomal protein L31 type B, 50S ribosomal protein L32, 50S ribosomal protein L33, 50S ribosomal protein L34, 50S ribosomal protein L35, 50S ribosomal protein L36/RNA Complex Functional site 1) chain F residue 57-73 type prosite sequence LELITGQKPLVTKAKKS description RIBOSOMAL_L5 Ribosomal protein L5 signature. LelITGQkpLvTkAKkS source prosite : PS00358 2) chain I residue 60-86 type prosite sequence AVIVRTKSGVRRNDGSYIKFDENACVI description RIBOSOMAL_L14 Ribosomal protein L14 signature. AVIVrtksgvrrn.DGsyikFdeNacVI source prosite : PS00049 3) chain 3 residue 5-31 type prosite sequence KTHRGAAKRVKRTASGQLKRSRAFTSH description RIBOSOMAL_L35 Ribosomal protein L35 signature. KTHrGAaKRVkrtasgqlkrsraft.SH source prosite : PS00936 4) chain K residue 134-137 type prosite sequence REEL description ER_TARGET Endoplasmic reticulum targeting sequence. REEL source prosite : PS00014 5) chain K residue 59-70 type prosite sequence KRGGKVWIKIFP description RIBOSOMAL_L16_1 Ribosomal protein L16 signature 1. KRgGKVWIKIFP source prosite : PS00586 6) chain K residue 82-93 type prosite sequence RMGAGKGAVEGW description RIBOSOMAL_L16_2 Ribosomal protein L16 signature 2. RMGaGKGavegW source prosite : PS00701 7) chain 4 residue 11-36 type prosite sequence CEKCKVIKRKGKVMVICENPKHKQRQ description RIBOSOMAL_L36 Ribosomal protein L36 signature. CekCkvIkRkgkVmViCenp.KHkQrQ source prosite : PS00828 8) chain L residue 30-52 type prosite sequence IETTEARAKEVRSVVEKLITLGK description RIBOSOMAL_L17 Ribosomal protein L17 signature. IeTTeaRaKevrsvvEkLITlGK source prosite : PS01167 9) chain 1 residue 17-36 type prosite sequence YITTKNKRNNPERIEMKKYC description RIBOSOMAL_L33 Ribosomal protein L33 signature. YiTtKNkrnnPerIEmkKYC source prosite : PS00582 10) chain C residue 218-229 type prosite sequence PTVRGSVMNPND description RIBOSOMAL_L2 Ribosomal protein L2 signature. PtvRGSVmNPnD source prosite : PS00467 11) chain J residue 110-140 type prosite sequence KILGNGSLDKKLTVKAHKFSASAAEAIDAKG description RIBOSOMAL_L15 Ribosomal protein L15 signature. KILGnGsLdkk..LtVkahkFSasAaeaIdakG source prosite : PS00475 12) chain 2 residue 3-22 type prosite sequence KRTYQPNKRKHSKVHGFRKR description RIBOSOMAL_L34 Ribosomal protein L34 signature. KRTYQpnkrkHskvh.GFrkR source prosite : PS00784 13) chain U residue 42-56 type prosite sequence GSILYRQRGTKIYPG description RIBOSOMAL_L27 Ribosomal protein L27 signature. GsILyRQRGtkiypG source prosite : PS00831 14) chain S residue 6-23 type prosite sequence GDNVKVIAGKDKGKEGKV description RIBOSOMAL_L24 Ribosomal protein L24 signature. GDnVkVIaGkdKGke.GkV source prosite : PS01108 15) chain H residue 106-128 type prosite sequence IKGMLPSTRLGEKQGKKLFVYGG description RIBOSOMAL_L13 Ribosomal protein L13 signature. IKGMLPstrl.GEkqgkkLfVYgG source prosite : PS00783 16) chain G residue 154-162 type prosite sequence PEPYKGKGI description RIBOSOMAL_L6_1 Ribosomal protein L6 signature 1. PEpYKGKGI source prosite : PS00525 17) chain D residue 110-133 type prosite sequence FVAGDVIDVTGVSKGKGFQGAIKR description RIBOSOMAL_L3 Ribosomal protein L3 signature. FvagdviDvtGvSkGKGfqGaikR source prosite : PS00474 18) chain N residue 88-103 type prosite sequence VKRRGKVRRAKLYYLR description RIBOSOMAL_L19 Ribosomal protein L19 signature. VkRrGKVR.RAKLYYLR source prosite : PS01015 19) chain O residue 54-70 type prosite sequence KRDFRKLWITRINAAAR description RIBOSOMAL_L20 Ribosomal protein L20 signature. KrdfRkLWITRINaaaR source prosite : PS00937

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