eF-site ID 6rtm-A PDB Code 6rtm Chain A click to enlarge Title Thioredoxin glutathione reductase from Schistosoma mansoni in complex with 1-[(dimethylamino)methyl]-2-naphthol at 2 hour of soaking Classification FLAVOPROTEIN Compound Thioredoxin glutathione reductase Source (G4V8J4_SCHMA) Sequence A:  TSQWLRKTVDSAAVILFSKTTCPYCKKVKDVLAEAKIKHA TIELDQLSNGSAIQKCLASFSKIETVPQMFVRGKFIGDSQ TVLKYYSNDELAGIVNESKYDYDLIVIGGGSGGLAAGKEA AKYGAKTAVLDYVEPTPIGTTWGLGGTCVNVGCIPKKLMH QAGLLSHALEDAEHFGWSLDRSKISHNWSTMVEGVQSHIG SLNWGYKVALRDNQVTYLNAKGRLISPHEVQITDKNQKVS TITGNKIILATGERPKYPEIPGAVEYGITSDDLFSLPYFP GKTLVIGASYVALECAGFLASLGGDVTVMVRSILLRGFDQ QMAEKVGDYMENHGVKFAKLCVPDEIKQLKVVDTENNKPG LLLVKGHYTDGKKFEEEFETVIFAVGREPQLSKVLCETVG VKLDKNGRVVCTDDEQTTVSNVYAIGDINAGKPQLTPVAI QAGRYLARRLFAGATELTDYSNVATTVFTPLEYGACGLSE EDAIEKYGDKDIEVYHSNFKPLEWTVAHREDNVCYMKLVC RKSDNMRVLGLHVLGPNAGEITQGYAVAIKMGATKADFDR TIGIHPTCSETFTTLHVTKKSGVSPIV Description Functional site 1) chain A residue 113 type sequence I description binding site for residue FAD A 601 source : AC1 2) chain A residue 114 type sequence G description binding site for residue FAD A 601 source : AC1 3) chain A residue 116 type sequence G description binding site for residue FAD A 601 source : AC1 4) chain A residue 117 type sequence S description binding site for residue FAD A 601 source : AC1 5) chain A residue 118 type sequence G description binding site for residue FAD A 601 source : AC1 6) chain A residue 137 type sequence D description binding site for residue FAD A 601 source : AC1 7) chain A residue 138 type sequence Y description binding site for residue FAD A 601 source : AC1 8) chain A residue 152 type sequence G description binding site for residue FAD A 601 source : AC1 9) chain A residue 153 type sequence T description binding site for residue FAD A 601 source : AC1 10) chain A residue 154 type sequence C description binding site for residue FAD A 601 source : AC1 11) chain A residue 158 type sequence G description binding site for residue FAD A 601 source : AC1 12) chain A residue 159 type sequence C description binding site for residue FAD A 601 source : AC1 13) chain A residue 162 type sequence K description binding site for residue FAD A 601 source : AC1 14) chain A residue 226 type sequence A description binding site for residue FAD A 601 source : AC1 15) chain A residue 228 type sequence G description binding site for residue FAD A 601 source : AC1 16) chain A residue 256 type sequence A description binding site for residue FAD A 601 source : AC1 17) chain A residue 257 type sequence T description binding site for residue FAD A 601 source : AC1 18) chain A residue 258 type sequence G description binding site for residue FAD A 601 source : AC1 19) chain A residue 296 type sequence Y description binding site for residue FAD A 601 source : AC1 20) chain A residue 393 type sequence R description binding site for residue FAD A 601 source : AC1 21) chain A residue 400 type sequence V description binding site for residue FAD A 601 source : AC1 22) chain A residue 432 type sequence G description binding site for residue FAD A 601 source : AC1 23) chain A residue 433 type sequence D description binding site for residue FAD A 601 source : AC1 24) chain A residue 440 type sequence Q description binding site for residue FAD A 601 source : AC1 25) chain A residue 441 type sequence L description binding site for residue FAD A 601 source : AC1 26) chain A residue 442 type sequence T description binding site for residue FAD A 601 source : AC1 27) chain A residue 443 type sequence P description binding site for residue FAD A 601 source : AC1 28) chain A residue 571 type sequence H description binding site for residue FAD A 601 source : AC1 29) chain A residue 572 type sequence P description binding site for residue FAD A 601 source : AC1 30) chain A residue 488 type sequence D description binding site for residue PGE A 602 source : AC2 31) chain A residue 491 type sequence E description binding site for residue PGE A 602 source : AC2 32) chain A residue 492 type sequence K description binding site for residue PGE A 602 source : AC2 33) chain A residue 138 type sequence Y description binding site for residue PGE A 603 source : AC3 34) chain A residue 225 type sequence N description binding site for residue PGE A 603 source : AC3 35) chain A residue 227 type sequence K description binding site for residue PGE A 603 source : AC3 36) chain A residue 239 type sequence T description binding site for residue PGE A 603 source : AC3 37) chain A residue 240 type sequence D description binding site for residue PGE A 603 source : AC3 38) chain A residue 241 type sequence K description binding site for residue PGE A 603 source : AC3 39) chain A residue 447 type sequence Q description binding site for residue K A 604 source : AC4 40) chain A residue 565 type sequence D description binding site for residue K A 604 source : AC4 41) chain A residue 567 type sequence T description binding site for residue K A 604 source : AC4 42) chain A residue 579 type sequence T description binding site for residue K A 604 source : AC4 43) chain A residue 316 type sequence V description binding site for residue KJH A 605 source : AC5 44) chain A residue 320 type sequence L description binding site for residue KJH A 605 source : AC5 45) chain A residue 330 type sequence E description binding site for residue KJH A 605 source : AC5 46) chain A residue 334 type sequence D description binding site for residue KJH A 605 source : AC5 47) chain A residue 343 type sequence F description binding site for residue KJH A 605 source : AC5 48) chain A residue 345 type sequence K description binding site for residue KJH A 605 source : AC5 49) chain A residue 151-161 type prosite sequence GGTCVNVGCIP description PYRIDINE_REDOX_1 Pyridine nucleotide-disulphide oxidoreductases class-I active site. GGtCVnvGCIP source prosite : PS00076 50) chain A residue 20-38 type prosite sequence VILFSKTTCPYCKKVKDVL description THIOREDOXIN_1 Thioredoxin family active site. VIlFSktTCPYCKkVkdvL source prosite : PS00194 51) chain A residue 22-38 type prosite sequence LFSKTTCPYCKKVKDVL description GLUTAREDOXIN_1 Glutaredoxin active site. LFskttCPYCkkVkdvL source prosite : PS00195

Display surface Download Links