eF-site/Summary 6roj-C

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Title	Cryo-EM structure of the activated Drs2p-Cdc50p
Classification	LIPID TRANSPORT
Compound	Probable phospholipid-transporting ATPase DRS2,Oxaloacetate decarboxylase alpha chain
Source	(CDC50_YEAST)

Sequence	C:	TSKKPPNTAFRQQRLKAWQPILSPQSVLPLLIFVACIFTP IGIGLIVSATKVQDLTIDYSHCDTKASTTAFEDIPKKYIK YHFKSKVENKPQWRLTENENGEQSCELQFEIPNDIKKSIF IYYKITNFYQNHRRYVQSFDTKQILGEPIKKDDLDTSCSP IRSREDKIIYPCGLIANSMFNDTFSQVLSGIDDTEDYNLT NKHISWSIDRHRFKTTKYNASDIVPPPNWMKKYPDGYTDE NLPDIHTWEEFQVWMRTAAFPKFYKLTLKNESASLPKGKY QMNIELNYPISLFGGTKSFVLTTNGAIGGRNMSLGVLYLI VAGLCALFGIIFLVKLIFQP

Description	(1)	Probable phospholipid-transporting ATPase DRS2,Oxaloacetate decarboxylase alpha chain (E.C.7.6.2.1,7.2.4.2), Cell division control protein 50

Functional site


1)	chain	C
	residue	329
	type	CARBOHYD
	sequence	N
	description	N-linked (GlcNAc...) asparagine => ECO:0000255
	source	Swiss-Prot : SWS_FT_FI7

2)	chain	C
	residue	45-65
	type	TRANSMEM
	sequence	VLPLLIFVACIFTPIGIGLIV
	description	Helical => ECO:0000255
	source	Swiss-Prot : SWS_FT_FI2

3)	chain	C
	residue	332-352
	type	TRANSMEM
	sequence	LGVLYLIVAGLCALFGIIFLV
	description	Helical => ECO:0000255
	source	Swiss-Prot : SWS_FT_FI2

4)	chain	C
	residue	66-331
	type	TOPO_DOM
	sequence	SATKVQDLTIDYSHCDTKASTTAFEDIPKKYIKYHFKSKV ENKPQWRLTENENGEQSCELQFEIPNDIKKSIFIYYKITN FYQNHRRYVQSFDTKQILGEPIKKDDLDTSCSPIRSREDK IIYPCGLIANSMFNDTFSQVLSGIDDTEDYNLTNKHISWS IDRHRFKTTKYNASDIVPPPNWMKKYPDGYTDENLPDIHT WEEFQVWMRTAAFPKFYKLTLKNESASLPKGKYQMNIELN YPISLFGGTKSFVLTTNGAIGGRNMS
	description	Lumenal => ECO:0000255
	source	Swiss-Prot : SWS_FT_FI3

5)	chain	C
	residue	199
	type	CARBOHYD
	sequence	N
	description	N-linked (GlcNAc...) asparagine => ECO:0000269\|PubMed:31243363, ECO:0000269\|PubMed:31515475
	source	Swiss-Prot : SWS_FT_FI4

6)	chain	C
	residue	288
	type	CARBOHYD
	sequence	N
	description	N-linked (GlcNAc...) asparagine => ECO:0000269\|PubMed:31243363, ECO:0000269\|PubMed:31515475
	source	Swiss-Prot : SWS_FT_FI4

7)	chain	C
	residue	216
	type	CARBOHYD
	sequence	N
	description	N-linked (GlcNAc...) asparagine => ECO:0000269\|PubMed:31243363, ECO:0000269\|PubMed:31515475, ECO:0007744\|PDB:7OH6, ECO:0007744\|PDB:7OH7
	source	Swiss-Prot : SWS_FT_FI5

8)	chain	C
	residue	237
	type	CARBOHYD
	sequence	N
	description	N-linked (GlcNAc...) asparagine => ECO:0000269\|PubMed:31243363
	source	Swiss-Prot : SWS_FT_FI6