eF-site ID 6rn8-B PDB Code 6rn8 Chain B click to enlarge Title RIP2 Kinase Catalytic Domain complex with 2(4[(1,3benzothiazol5yl)amino]6(2methylpropane2sulfonyl)quinazolin7yl)oxy)ethyl phosphate Classification TRANSFERASE Compound Receptor-interacting serine/threonine-protein kinase 2 Source (RIPK2_HUMAN) Sequence B:  AICSALPTIPYHKLADLRYLSRGAGTVSSARHADWRVQVA VKHLHIPLLDSERKDVLREAEILHKARFSYILPILGICNE PEFLGIVTEYMPNGSLNELLHRKTEYPDVAWPLRFRILHE IALGVNYLHNMTPPLLHHDLKTQNILLDNEFHVKIADFGL SKWRMEGGTIIYMPPENYEPSIKHDIYSYAVITWEVLSRK QPFEDVTNPLQIMYSVSQGHRPVINEESLPYDIPHRARMI SLIESGWAQNPDERPSFLKCLIELEPVLRTFEEITFLEAV IQLK Description Functional site 1) chain B residue 112 type sequence E description binding site for residue CA B 401 source : AC2 2) chain B residue 24 type sequence L description binding site for residue K9T B 402 source : AC3 3) chain B residue 25 type sequence S description binding site for residue K9T B 402 source : AC3 4) chain B residue 32 type sequence V description binding site for residue K9T B 402 source : AC3 5) chain B residue 45 type sequence A description binding site for residue K9T B 402 source : AC3 6) chain B residue 47 type sequence K description binding site for residue K9T B 402 source : AC3 7) chain B residue 66 type sequence E description binding site for residue K9T B 402 source : AC3 8) chain B residue 70 type sequence L description binding site for residue K9T B 402 source : AC3 9) chain B residue 79 type sequence L description binding site for residue K9T B 402 source : AC3 10) chain B residue 95 type sequence T description binding site for residue K9T B 402 source : AC3 11) chain B residue 96 type sequence E description binding site for residue K9T B 402 source : AC3 12) chain B residue 97 type sequence Y description binding site for residue K9T B 402 source : AC3 13) chain B residue 98 type sequence M description binding site for residue K9T B 402 source : AC3 14) chain B residue 101 type sequence G description binding site for residue K9T B 402 source : AC3 15) chain B residue 105 type sequence E description binding site for residue K9T B 402 source : AC3 16) chain B residue 153 type sequence L description binding site for residue K9T B 402 source : AC3 17) chain B residue 163 type sequence A description binding site for residue K9T B 402 source : AC3 18) chain B residue 164 type sequence D description binding site for residue K9T B 402 source : AC3 19) chain B residue 146 type ACT_SITE sequence D description Proton acceptor => ECO:0000269|PubMed:9705938 source Swiss-Prot : SWS_FT_FI1 20) chain B residue 209 type CROSSLNK sequence K description Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin) => ECO:0000269|PubMed:18079694 source Swiss-Prot : SWS_FT_FI10 21) chain B residue 24 type BINDING sequence L description BINDING => ECO:0000255|PROSITE-ProRule:PRU00159 source Swiss-Prot : SWS_FT_FI2 22) chain B residue 47 type BINDING sequence K description source Swiss-Prot : SWS_FT_FI3 23) chain B residue 149 type MOD_RES sequence T description (Microbial infection) O-acetylthreonine; by Yersinia YopJ => ECO:0000269|PubMed:22520462 source Swiss-Prot : SWS_FT_FI4 24) chain B residue 189 type MOD_RES sequence T description (Microbial infection) O-acetylthreonine; by Yersinia YopJ => ECO:0000269|PubMed:22520462 source Swiss-Prot : SWS_FT_FI4 25) chain B residue 168 type MOD_RES sequence S description Phosphoserine => ECO:0007744|PubMed:19369195 source Swiss-Prot : SWS_FT_FI5

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