eF-site ID 6rkg-C PDB Code 6rkg Chain C click to enlarge Title 1.32 A RESOLUTION OF SPOROSARCINA PASTEURII UREASE INHIBITED IN THE PRESENCE OF NBPTO AT pH 7.5 Classification HYDROLASE Compound Urease subunit gamma Source ORGANISM_SCIENTIFIC: Sporosarcina pasteurii; Sequence C:  MKINRQQYAESYGPTVGDQVRLADTDLWIEVEKDYTTYGD EANFGGGKVLREGMGENGTYTRTENVLDLLLTNALILDYT GIYKADIGVKDGYIVGIGKGGNPDIMDGVTPNMIVGTATE VIAAEGKIVTAGGIDTHVHFINPDQVDVALANGITTLFGG GTGPAEGSKATTVTPGPWNIEKMLKSTEGLPINVGILGKG HGSSIAPIMEQIDAGAAGLXIHEDWGATPASIDRSLTVAD EADVQVAIHSDTLNEAGFLEDTLRAINGRVIHSFHVEGAG GGHAPDIMAMAGHPNVLPSSTNPTRPFTVNTIDEHLDMLM VCHHLKQNIPEDVAFADSRIRPETIAAEDILHDLGIISMM STDALAMGRAGEMVLRTWQTADKMKKQRGPLAEEKNGSDN FRAKRYVSKYTINPAIAQGIAHEVGSIEEGKFADLVLWEP KFFGVKADRVIKGGIIAYAQIGDPSASIPTPQPVMGRRMY GTVGDLIHDTNITFMSKSSIQQGVPAKLGLKRRIGTVKNC RNIGKKDMKWNDVTTDIDINPETYEVKVDGEVLTCEPVKE LPMAQRYFLF Description Functional site 1) chain C residue 309 type sequence V description binding site for residue EDO A 201 source : AC1 2) chain C residue 310 type sequence N description binding site for residue EDO A 201 source : AC1 3) chain C residue 559 type sequence K description binding site for residue EDO A 201 source : AC1 4) chain C residue 568 type sequence F description binding site for residue EDO A 202 source : AC2 5) chain C residue 570 type sequence F description binding site for residue EDO A 202 source : AC2 6) chain C residue 229 type sequence P description binding site for residue EDO B 201 source : AC6 7) chain C residue 220 type sequence X description binding site for residue NI C 601 source : AC8 8) chain C residue 222 type sequence H description binding site for residue NI C 601 source : AC8 9) chain C residue 249 type sequence H description binding site for residue NI C 601 source : AC8 10) chain C residue 275 type sequence H description binding site for residue NI C 601 source : AC8 11) chain C residue 280 type sequence G description binding site for residue NI C 601 source : AC8 12) chain C residue 137 type sequence H description binding site for residue NI C 602 source : AC9 13) chain C residue 139 type sequence H description binding site for residue NI C 602 source : AC9 14) chain C residue 220 type sequence X description binding site for residue NI C 602 source : AC9 15) chain C residue 363 type sequence D description binding site for residue NI C 602 source : AC9 16) chain C residue 34 type sequence D description binding site for residue EDO C 603 source : AD1 17) chain C residue 36 type sequence T description binding site for residue EDO C 603 source : AD1 18) chain C residue 38 type sequence Y description binding site for residue EDO C 603 source : AD1 19) chain C residue 7 type sequence Q description binding site for residue EDO C 604 source : AD2 20) chain C residue 11 type sequence S description binding site for residue EDO C 604 source : AD2 21) chain C residue 286 type sequence D description binding site for residue EDO C 605 source : AD3 22) chain C residue 289 type sequence A description binding site for residue EDO C 605 source : AD3 23) chain C residue 537 type sequence I description binding site for residue EDO C 605 source : AD3 24) chain C residue 539 type sequence I description binding site for residue EDO C 605 source : AD3 25) chain C residue 93 type sequence Y description binding site for residue EDO C 606 source : AD4 26) chain C residue 423 type sequence E description binding site for residue EDO C 606 source : AD4 27) chain C residue 501 type sequence Q description binding site for residue EDO C 606 source : AD4 28) chain C residue 513 type sequence R description binding site for residue EDO C 606 source : AD4 29) chain C residue 514 type sequence I description binding site for residue EDO C 606 source : AD4 30) chain C residue 33 type sequence K description binding site for residue EDO C 607 source : AD5 31) chain C residue 35 type sequence Y description binding site for residue EDO C 607 source : AD5 32) chain C residue 536 type sequence D description binding site for residue EDO C 608 source : AD6 33) chain C residue 538 type sequence D description binding site for residue EDO C 608 source : AD6 34) chain C residue 547 type sequence K description binding site for residue EDO C 608 source : AD6 35) chain C residue 549 type sequence D description binding site for residue EDO C 608 source : AD6 36) chain C residue 550 type sequence G description binding site for residue EDO C 608 source : AD6 37) chain C residue 337 type sequence D description binding site for residue EDO C 609 source : AD7 38) chain C residue 338 type sequence S description binding site for residue EDO C 609 source : AD7 39) chain C residue 544 type sequence Y description binding site for residue EDO C 609 source : AD7 40) chain C residue 35 type sequence Y description binding site for residue EDO C 610 source : AD8 41) chain C residue 83 type sequence Y description binding site for residue EDO C 610 source : AD8 42) chain C residue 97 type sequence I description binding site for residue EDO C 610 source : AD8 43) chain C residue 429 type sequence E description binding site for residue EDO C 610 source : AD8 44) chain C residue 143 type sequence P description binding site for residue EDO C 611 source : AD9 45) chain C residue 189 type sequence G description binding site for residue EDO C 611 source : AD9 46) chain C residue 478 type sequence R description binding site for residue EDO C 611 source : AD9 47) chain C residue 309 type sequence V description binding site for residue EDO C 612 source : AE1 48) chain C residue 557 type sequence P description binding site for residue EDO C 612 source : AE1 49) chain C residue 34 type sequence D description binding site for residue EDO C 613 source : AE2 50) chain C residue 35 type sequence Y description binding site for residue EDO C 613 source : AE2 51) chain C residue 317 type sequence D description binding site for residue EDO C 614 source : AE3 52) chain C residue 327 type sequence Q description binding site for residue EDO C 614 source : AE3 53) chain C residue 65 type sequence N description binding site for residue SO4 C 615 source : AE4 54) chain C residue 204 type sequence S description binding site for residue SO4 C 615 source : AE4 55) chain C residue 205 type sequence I description binding site for residue SO4 C 615 source : AE4 56) chain C residue 558 type sequence V description binding site for residue SO4 C 616 source : AE5 57) chain C residue 559 type sequence K description binding site for residue SO4 C 616 source : AE5 58) chain C residue 560 type sequence E description binding site for residue SO4 C 616 source : AE5 59) chain C residue 137 type sequence H description binding site for residue 2PA C 617 source : AE6 60) chain C residue 139 type sequence H description binding site for residue 2PA C 617 source : AE6 61) chain C residue 170 type sequence A description binding site for residue 2PA C 617 source : AE6 62) chain C residue 220 type sequence X description binding site for residue 2PA C 617 source : AE6 63) chain C residue 222 type sequence H description binding site for residue 2PA C 617 source : AE6 64) chain C residue 249 type sequence H description binding site for residue 2PA C 617 source : AE6 65) chain C residue 275 type sequence H description binding site for residue 2PA C 617 source : AE6 66) chain C residue 280 type sequence G description binding site for residue 2PA C 617 source : AE6 67) chain C residue 323 type sequence H description binding site for residue 2PA C 617 source : AE6 68) chain C residue 363 type sequence D description binding site for residue 2PA C 617 source : AE6 69) chain C residue 366 type sequence A description binding site for residue 2PA C 617 source : AE6 70) chain C residue 367 type sequence M description binding site for residue 2PA C 617 source : AE6 71) chain C residue 11 type sequence S description binding site for residue SO4 C 618 source : AE7 72) chain C residue 12 type sequence Y description binding site for residue SO4 C 618 source : AE7 73) chain C residue 43 type sequence N description binding site for residue SO4 C 618 source : AE7 74) chain C residue 48 type sequence K description binding site for residue SO4 C 618 source : AE7 75) chain C residue 326 type sequence K description binding site for residue SO4 C 618 source : AE7 76) chain C residue 329 type sequence I description binding site for residue SO4 C 618 source : AE7 77) chain C residue 511 type sequence K description binding site for residue SO4 C 619 source : AE8 78) chain C residue 511 type sequence K description binding site for residue SO4 C 619 source : AE8 79) chain C residue 511 type sequence K description binding site for residue SO4 C 619 source : AE8 80) chain C residue 518 type sequence K description binding site for residue SO4 C 620 source : AE9 81) chain C residue 518 type sequence K description binding site for residue SO4 C 620 source : AE9 82) chain C residue 220 type MOD_RES sequence X description N6-carboxylysine => ECO:0000255|HAMAP-Rule:MF_01953, ECO:0000269|PubMed:10368287, ECO:0000269|PubMed:10766443, ECO:0000269|PubMed:11713685, ECO:0000269|PubMed:15038715, ECO:0000269|PubMed:30969470, ECO:0000269|DOI:10.1007/s007750050231, ECO:0007744|PDB:1IE7, ECO:0007744|PDB:1S3T, ECO:0007744|PDB:1UBP, ECO:0007744|PDB:2UBP, ECO:0007744|PDB:4UBP source Swiss-Prot : SWS_FT_FI5 83) chain C residue 323 type ACT_SITE sequence H description Proton donor => ECO:0000305 source Swiss-Prot : SWS_FT_FI1 84) chain C residue 320-336 type prosite sequence MVCHHLKQNIPEDVAFA description UREASE_2 Urease active site. MVCHHLkqnIpeDVaFA source prosite : PS00145 85) chain C residue 130-143 type prosite sequence TAGGIDTHVHFINP description UREASE_1 Urease nickel ligands signature. TAGGIDtHVHfinP source prosite : PS01120 86) chain C residue 137 type BINDING sequence H description BINDING => ECO:0000255|HAMAP-Rule:MF_01953, ECO:0000269|PubMed:10368287, ECO:0000269|PubMed:10766443, ECO:0000269|PubMed:11713685, ECO:0000269|PubMed:15038715, ECO:0000269|PubMed:30969470, ECO:0000269|DOI:10.1007/s007750050231 source Swiss-Prot : SWS_FT_FI2 87) chain C residue 275 type BINDING sequence H description BINDING => ECO:0000255|HAMAP-Rule:MF_01953, ECO:0000269|PubMed:10368287, ECO:0000269|PubMed:10766443, ECO:0000269|PubMed:11713685, ECO:0000269|PubMed:15038715, ECO:0000269|PubMed:30969470, ECO:0000269|DOI:10.1007/s007750050231 source Swiss-Prot : SWS_FT_FI2 88) chain C residue 363 type BINDING sequence D description BINDING => ECO:0000255|HAMAP-Rule:MF_01953, ECO:0000269|PubMed:10368287, ECO:0000269|PubMed:10766443, ECO:0000269|PubMed:11713685, ECO:0000269|PubMed:15038715, ECO:0000269|PubMed:30969470, ECO:0000269|DOI:10.1007/s007750050231 source Swiss-Prot : SWS_FT_FI2 89) chain C residue 139 type BINDING sequence H description BINDING => ECO:0000269|PubMed:30969470 source Swiss-Prot : SWS_FT_FI3 90) chain C residue 170 type BINDING sequence A description BINDING => ECO:0000269|PubMed:30969470 source Swiss-Prot : SWS_FT_FI3 91) chain C residue 222 type BINDING sequence H description BINDING => ECO:0000269|PubMed:30969470 source Swiss-Prot : SWS_FT_FI3 92) chain C residue 249 type BINDING sequence H description BINDING => ECO:0000269|PubMed:30969470 source Swiss-Prot : SWS_FT_FI3 93) chain C residue 366 type BINDING sequence A description BINDING => ECO:0000269|PubMed:30969470 source Swiss-Prot : SWS_FT_FI3 94) chain C residue 220 type BINDING sequence X description via carbamate group => ECO:0000255|HAMAP-Rule:MF_01953, ECO:0000269|PubMed:10368287, ECO:0000269|PubMed:10766443, ECO:0000269|PubMed:11713685, ECO:0000269|PubMed:15038715, ECO:0000269|PubMed:30969470, ECO:0000269|DOI:10.1007/s007750050231 source Swiss-Prot : SWS_FT_FI4

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