eF-site ID 6r9x-A PDB Code 6r9x Chain A click to enlarge Title Human Cyclophilin D in complex with N-cyclopentyl-N'-pyridin-2-ylmethyl-oxalamide Classification ISOMERASE Compound Peptidyl-prolyl cis-trans isomerase F, mitochondrial Source (PPIF_HUMAN) Sequence A:  GNPLVYLDVDANGKPLGRVVLELKADVVPKTAENFRALCT GEKGFGYKGSTFHRVIPSFMCQAGDFTNHNGTGGKSIYGS RFPDENFTLKHVGPGVLSMANAGPNTNGSQFFICTIKTDW LDGKHVVFGHVIEGMDVVKKIESFGSKSGRTSKKIVITDC GQLS Description Functional site 1) chain A residue 97 type sequence R description binding site for residue JW2 A 301 source : AC1 2) chain A residue 102 type sequence F description binding site for residue JW2 A 301 source : AC1 3) chain A residue 103 type sequence M description binding site for residue JW2 A 301 source : AC1 4) chain A residue 105 type sequence Q description binding site for residue JW2 A 301 source : AC1 5) chain A residue 114 type sequence G description binding site for residue JW2 A 301 source : AC1 6) chain A residue 143 type sequence A description binding site for residue JW2 A 301 source : AC1 7) chain A residue 144 type sequence N description binding site for residue JW2 A 301 source : AC1 8) chain A residue 153 type sequence Q description binding site for residue JW2 A 301 source : AC1 9) chain A residue 155 type sequence F description binding site for residue JW2 A 301 source : AC1 10) chain A residue 168 type sequence H description binding site for residue JW2 A 301 source : AC1 11) chain A residue 90-107 type prosite sequence YKGSTFHRVIPSFMCQAG description CSA_PPIASE_1 Cyclophilin-type peptidyl-prolyl cis-trans isomerase signature. YkgStFHRVIpsFMcQAG source prosite : PS00170 12) chain A residue 67 type MOD_RES sequence K description N6-succinyllysine; alternate => ECO:0000250|UniProtKB:Q99KR7 source Swiss-Prot : SWS_FT_FI1 13) chain A residue 86 type MOD_RES sequence K description N6-succinyllysine => ECO:0000250|UniProtKB:Q99KR7 source Swiss-Prot : SWS_FT_FI2 14) chain A residue 175 type MOD_RES sequence I description N6-succinyllysine => ECO:0000250|UniProtKB:Q99KR7 source Swiss-Prot : SWS_FT_FI2 15) chain A residue 190 type MOD_RES sequence K description N6-succinyllysine => ECO:0000250|UniProtKB:Q99KR7 source Swiss-Prot : SWS_FT_FI2 16) chain A residue 167 type MOD_RES sequence K description N6-acetyllysine => ECO:0000250|UniProtKB:Q99KR7 source Swiss-Prot : SWS_FT_FI3 17) chain A residue 203 type MOD_RES sequence C description S-nitrosocysteine => ECO:0000250|UniProtKB:Q99KR7 source Swiss-Prot : SWS_FT_FI4

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