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eF-site ID
|
6qtp-C |
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PDB Code
|
6qtp |
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Chain
|
C |
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click to enlarge
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Title
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2.37A structure of gepotidacin with S.aureus DNA gyrase and uncleaved DNA |
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Classification
|
ISOMERASE |
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Compound
|
DNA gyrase subunit B,DNA gyrase subunit B |
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Source
|
(6QTP) |
|
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Sequence
|
C: |
NERNITSEMRESFLDYAMSVIVARALPDVRDGLKPVHRRI
LYGLNEQGMTPDKSYKKSARIVGDVMGKYHPHGDSSIYEA
MVRMAQDFSYRYPLVDGQGNFGSMDGDGAAAMRYTEARMT
KITLELLRDINKDTIDFIDNYDGNEREPSVLPARFPNLLA
NGASGIAVGMATNIPPHNLTELINGVLSLSKNPDISIAEL
MEDIEGPDFPTAGLILGKSGIRRAYETGRGSIQMRSRAVI
EERGGGRQRIVVTEIPFQVNKARMIEKIAELVRDKKIDGI
TDLRDETSLRTGVRVVIDVRKDANASVILNNLYKQTPLQT
SFGVNMIALVNGRPKLINLKEALVHYLEHQKTVVRRRTQY
NLRKAKDRAHILEGLRIALDHIDEIISTIRESDTDKVAME
SLQQRFKLSEKQAQAILDMRLRRLTGLERDKIEAEYNELL
NYISELETILADEEVLLQLVRDELTEIRDRFGDDRRTEIQ
L
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Description
|
(1) |
DNA gyrase subunit B,DNA gyrase subunit B, DNA gyrase subunit A/DNA Complex
|
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Functional site
|
|
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1)
|
chain |
C |
| residue |
429 |
| type |
|
| sequence |
R
|
| description |
binding site for residue SO4 C 501
|
| source |
: AC5
|
|
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2)
|
chain |
C |
| residue |
68 |
| type |
|
| sequence |
A
|
| description |
binding site for residue JHN E 101
|
| source |
: AC6
|
|
|
3)
|
chain |
C |
| residue |
75 |
| type |
|
| sequence |
M
|
| description |
binding site for residue JHN E 101
|
| source |
: AC6
|
|
|
4)
|
chain |
C |
| residue |
83 |
| type |
|
| sequence |
D
|
| description |
binding site for residue JHN E 101
|
| source |
: AC6
|
|
|
5)
|
chain |
C |
| residue |
121 |
| type |
|
| sequence |
M
|
| description |
binding site for residue JHN E 101
|
| source |
: AC6
|
|
|
6)
|
chain |
C |
| residue |
123 |
| type |
ACT_SITE |
| sequence |
Y
|
| description |
O-(5'-phospho-DNA)-tyrosine intermediate => ECO:0000255|HAMAP-Rule:MF_01897
|
| source |
Swiss-Prot : SWS_FT_FI1
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