eF-site ID 6qpl-B PDB Code 6qpl Chain B click to enlarge Title Crystal structure of Spindlin1 in complex with the inhibitor MS31 Classification CELL CYCLE Compound Spindlin-1 Source (SPIN1_HUMAN) Sequence B:  NIVGCRIQHGWKEGNGPVTQWKGTVLDQVPVNPSLYLIKY DGFDCVYGLELNKDERVSALEVLPDRVLADTMIGKAVEHM FETEDGSKDEWRGMVLARAPVMNTWFYITYEKDPVLYMYQ LLDDYKEGDLRIMPSLVGKQVEYADGSKRTGMVIHQVEAK PSVYFIKFDDDFHIYVYDLVKTSAENLYFQ Description Functional site 1) chain B residue 153 type sequence G description binding site for residue MPD B 301 source : AC1 2) chain B residue 154 type sequence M description binding site for residue MPD B 301 source : AC1 3) chain B residue 171 type sequence E description binding site for residue MPD B 301 source : AC1 4) chain B residue 242 type sequence V description binding site for residue MPD B 301 source : AC1 5) chain B residue 255 type sequence V description binding site for residue MPD B 301 source : AC1 6) chain B residue 62 type sequence W description binding site for residue MPD B 302 source : AC2 7) chain B residue 72 type sequence W description binding site for residue MPD B 302 source : AC2 8) chain B residue 98 type sequence Y description binding site for residue MPD B 302 source : AC2 9) chain B residue 81 type sequence P description binding site for residue DMS B 303 source : AC3 10) chain B residue 185 type sequence Y description binding site for residue DMS B 303 source : AC3 11) chain B residue 186 type sequence K description binding site for residue DMS B 303 source : AC3 12) chain B residue 188 type sequence G description binding site for residue DMS B 303 source : AC3 13) chain B residue 95 type sequence D description binding site for residue JC5 B 305 source : AC5 14) chain B residue 139 type sequence H description binding site for residue JC5 B 305 source : AC5 15) chain B residue 141 type sequence F description binding site for residue JC5 B 305 source : AC5 16) chain B residue 151 type sequence W description binding site for residue JC5 B 305 source : AC5 17) chain B residue 170 type sequence Y description binding site for residue JC5 B 305 source : AC5 18) chain B residue 177 type sequence Y description binding site for residue JC5 B 305 source : AC5 19) chain B residue 179 type sequence Y description binding site for residue JC5 B 305 source : AC5 20) chain B residue 184 type sequence D description binding site for residue JC5 B 305 source : AC5 21) chain B residue 191 type sequence R description binding site for residue GLY B 306 source : AC6 22) chain B residue 269 type sequence Q description binding site for residue GLY B 306 source : AC6 23) chain B residue 101 type sequence E description binding site for residue PO4 B 307 source : AC7 24) chain B residue 107 type sequence R description binding site for residue PO4 B 307 source : AC7 25) chain B residue 146 type sequence G description binding site for residue PO4 B 307 source : AC7 26) chain B residue 224 type sequence D description binding site for residue GOL B 308 source : AC8 27) chain B residue 225 type sequence G description binding site for residue GOL B 308 source : AC8 28) chain B residue 226 type sequence S description binding site for residue GOL B 308 source : AC8 29) chain B residue 173 type SITE sequence D description Histone H3K4me3 and H3R8me2a binding source Swiss-Prot : SWS_FT_FI1 30) chain B residue 180 type SITE sequence Q description Histone H3K4me3 and H3R8me2a binding source Swiss-Prot : SWS_FT_FI1 31) chain B residue 184 type SITE sequence D description Histone H3K4me3 and H3R8me2a binding source Swiss-Prot : SWS_FT_FI1 32) chain B residue 109 type MOD_RES sequence S description Phosphoserine; by AURKA => ECO:0000269|PubMed:22258766 source Swiss-Prot : SWS_FT_FI2

Display surface Download Links