eF-site ID 6qpf-ABCDEFGHIJKL PDB Code 6qpf Chain A, B, C, D, E, F, G, H, I, J, K, L Title Influenza A virus Polymerase Heterotrimer A/duck/Fujian/01/2002(H5N1) Classification RNA BINDING PROTEIN Compound Polymerase acidic protein Source (D3YNB5_9INFA) Sequence A:  MEDFVRQCFNPMIVELAEKAMKEYGEDPKIETNKFAAICT HLEVCFMYSDFHFIDERGESIIVESGDPNALLKHRFEIIE GRDRTMAWTVVNSICNTTGAEKPKFLPDLYDYKENRFIEI GVTRREVHIYYLEKANKIKSEKTHIHIFPFTGEEMATKAD YTLDEESRARIKTRLFTIRQEMASRGLWDSFRQSERGEET IEERFEITGTMRRLADQSLPPNFSSLENFRAYVDGFEPNG CIEGKLSQMSKEVNARIEPFLKTTPRPLRLPDGPPCSQRS KFLLMDALKLSIEDPSHEGEGIPLYDAIKCMKTFFGWKEP NIIKPHEKGINPNYLLAWKQVLAELQDIENEEKIPKKKNM KKTSQLKWALGENMAPEKVDFEDCKDVSDLKQYDSDEPEP RSLASWIQSEFNKACELTDSSWIELDEIGEDVAPIEHIAS MRRNYFTAEVSHCRATEYIMKGVYINTALLNASCAAMDDF QLIPMISKCRTKEGRRKTNLYGFIIKGRSHLRNDTDVVNF VSMEFSLTDPRLEPHKWEKYCVLEIGDMLLRTAIGQVSRP MFLYVRTNGTSKIKMKWGMEMRRCLLQSLQQIESMIEAES SVKEKDMTKEFFENKSETWPIGESPKGVEEGSIGKVCRTL LAKSVFNSLYASPQLEGFSAESRRLLLIVQALRDNLEPGT FDLGGLYEAIEECLINDPWVLLNASWFNSFLTHALR B:  MDVNPTLLFLKVPAQNAISTTFPYTGDPPTGYTMDTVNRT HQYSEKGKWTTNTETGAPQLNPIDGPLPDNHEPSGYAQTD CVLEAMAFLEESHPGIFENSCLETMEVVQQTRVDKLTQGR QTYDWTLNRNQPAATALANTIEVFRSNDLTANESGRLIDF LKDVMESMDKEEMEITAHKKKQRLNKKSYLIRALTLNTTP GMQIRGFVYFVETLARSICEKLEQSGLPVGGNEKKAKLAN VVRKMMTNSQDTELSFTITGDNTKWNENQNPRMFLAMITY ITRNQPDWFRNVLSIAPIMFSNKMARLGKGYQIPAEMLAN IDLKYFNESTRKKIEKIRPLLIDGTASLSPGMMMGMFNML STVLGVSILNLGQKRYTKTTYWWDGLQSSDDFALIVNAPN HEGIQAGVDRFYRTCKLVGINMSKKKSYINRTGTFEFTSF FYRYGFVANFSMELPSFGVSGINESADMSIGVTVIKNNMI NNDLGPATAQMALQLFIKDYRYTYRCHRGDTQIQTRRSFE LKKLWEQTRSKAGLLVSDGGPNLYNIRNLHIPEVCLKWEL MDEDYQGRLCNPLNPFVSHKEIESANNAGPAKSMEYDAVA TTHSWIPKRNRLEDEQMYQKCCNLFEKFFPSSSYRRPVGI SSMVEAMVSRARIDARIDFESGRIKKEEFAEIMKICSTIE ELRRQ C:  MERIKELRDLMSQSRTREILTKTTVDHIAIIKKYTSGRQE KNPALRMKWMMAMKYPITADKRIMEMIPERNEQGQTLWSK VMVSSLAVTWWNRNGPTTSTVHYPKVYKTYFEKVERLKHG TFGPVHFRNQVKIRRRVDVNPGHADLSAKEAQDVIMEVVF PNEVGARILTLTITKEKKEELQDCKIAPLMVAYMLERELV RKTRFLPVAGGTSSVYIEVLHLTQGTCWEQMYTPGGEVRN DDVDQSLIIAARNIVRRATVSTDPLASLLEMCHSTQIGGI RMVDILRQNPTEEQAVDICKAAMGLRISSSFSFGGFTFKR TSGSSVKKEEEVLTGNLQTLKIRVHEGYEEFTMVGRRATA ILRKATRRLIQLIVSGRDEQSIAEAIIVAMVFSQEDCMIK AVRGDLNFVNRANQRLNPMHQLLRHFQKDAKVLFQNWGIE PIDNVMGMIGILPDMTPSTEMSLRGVRVSKMGVDEYSSTE RVVVSIDRFLRVRDQRGNVLLSPEEVSETQGTERLTITYS SSMMWEINGPESVLVNTYQWVIRNWETVKIQWSQDPTMLY NKMEFEPFQSLIPKAARGQYSGFVRTLFQQMRDVVGTFDT VQIIKLLPFTAAPPEQSRMQFSSLTVNVRGSGMRILVRGN SPVFNYNKATKRLTVLGKDAGALGFLILGKEDKRYGPALS INELSNLAKGEKANVLIGQGDVVLVMKRKRDSSILTDSQT ATKRIRM D:  MEDFVRQCFNPMIVELAEKAMKEYGEDPKIETNKFAAICT HLEVCFMYSDFHFIDERGESIIVESGDPNALLKHRFEIIE GRDRTMAWTVVNSICNTTGAEKPKFLPDLYDYKENRFIEI GVTRREVHIYYLEKANKIKSEKTHIHIFPFTGEEMATKAD YTLDEESRARIKTRLFTIRQEMASRGLWDSFRQSERGEET IEERFEITGTMRRLADQSLPPNFSSLENFRAYVDGFEPNG CIEGKLSQMSKEVNARIEPFLKTTPRPLRLPDGPPCSQRS KFLLMDALKLSIEDPSHEGEGIPLYDAIKCMKTFFGWKEP NIIKPHEKGINPNYLLAWKQVLAELQDIENEEKIPKKKNM KKTSQLKWALGENMAPEKVDFEDCKDVSDLKQYDSDEPEP RSLASWIQSEFNKACELTDSSWIELDEIGEDVAPIEHIAS MRRNYFTAEVSHCRATEYIMKGVYINTALLNASCAAMDDF QLIPMISKCRTKEGRRKTNLYGFIIKGRSHLRNDTDVVNF VSMEFSLTDPRLEPHKWEKYCVLEIGDMLLRTAIGQVSRP MFLYVRTNGTSKIKMKWGMEMRRCLLQSLQQIESMIEAES SVKEKDMTKEFFENKSETWPIGESPKGVEEGSIGKVCRTL LAKSVFNSLYASPQLEGFSAESRRLLLIVQALRDNLEPGT FDLGGLYEAIEECLINDPWVLLNASWFNSFLTHALR E:  MDVNPTLLFLKVPAQNAISTTFPYTGDPPTGYTMDTVNRT HQYSEKGKWTTNTETGAPQLNPIDGPLPDNHEPSGYAQTD CVLEAMAFLEESHPGIFENSCLETMEVVQQTRVDKLTQGR QTYDWTLNRNQPAATALANTIEVFRSNDLTANESGRLIDF LKDVMESMDKEEMKQRLNKKSYLIRALTLNTTPGMQIRGF VYFVETLARSICEKLEQSGLPVGGNEKKAKLANVVRKMMT NSQDTELSFTITGDNTKWNENQNPRMFLAMITYITRNQPD WFRNVLSIAPIMFSNKMIPAEMLANIDLKYFNESTRKKIE KIRPLLIDGTASLSPGMMMGMFNMLSTVLGVSILNLGQKR YTKTTYWWDGLQSSDDFALIVNAPNHEGIQAGVDRFYRTC KLVGINMSKKKSYINRTGTFEFTSFFYRYGFVANFSMELP SFGVSGINESADMSIGVTVIKNNMINNDLGPATAQMALQL FIKDYRYTYRCHRGDTQIQTRRSFELKKLWEQTRSKAGLL VSDGGPNLYNIRNLHIPEVCLKWELMDEDYQGRLCNPLNP FVSHKEIESANNAKSMEYDAVATTHSWIPDEQMYQKCCNL FEKFFPSSSYRRPVGISSMVEAMVSRARIDARIDFESGRI KKEEFAEIMKICSTIEELRRQ F:  MERIKELRDLMSQSRTREILTKTTVDHIAIIKKYTSGRQE KNPALRMKWMMAMKYPITADKRIMEMIPERNEQGQTLWSK TNDRVMVSSLAVTWWNRNGPTTSTVHYPKVYKTYFEKVER LKHGTFGPVHFRNQVKIRRRVDVNPGHADLSAKEAQDVIM EVVFPNEVGARILTLTITKEKKEELQDCKIAPLMVAYMLE RELVRKTRFLPVAGGTSSVYIEVLHLTQGTCWEQMYTPGG EVRNDDVDQSLIIAARNIVRRATVSTDPLASLLEMCHSTQ IGGIRMVDILRQNPTEEQAVDICKAAMGLRISSSFSFGGF TFKRTSGSSVKKEEEVLTGNLQTLKIRVHEGYEEFTMVGR RATAILRKATRRLIQLIVSGRDEQSIAEAIIVAMVFSQED CMIKAVRGDLNFVNRANQRLNPMHQLLRHFQKDAKVLFQN WGIEPIDNVMGMIGILPDMTPSTEMSLRGVRVSKMGVDEY SSTERVVVSIDRFLRVRDQRGNVLLSPEEVSETQGTERLT ITYSSSMMWEINGPESVLVNTYQWVIRNWETVKIQWSQDP TMLYNKMEFEPFQSLIPKAARGQYSGFVRTLFQQMRDVVG TFDTVQIIKLLPFTAAPPEQSRMQFSSLTVNVRGSGMRIL VRGNSPVFNYNKATKRLTVLGKDAGALGFLILGKEDKRYG PALSINELSNLAKGEKANVLIGQGDVVLVMKRKRDSSILT DSQTATKRIRM G:  MEDFVRQCFNPMIVELAEKAMKEYGEDPKIETNKFAAICT HLEVCFMYSDFHFIDERGESIIVESGDPNALLKHRFEIIE GRDRTMAWTVVNSICNTTGAEKPKFLPDLYDYKENRFIEI GVTRREVHIYYLEKANKIKSEKTHIHIFPFTGEEMATKAD YTLDEESRARIKTRLFTIRQEMASRGLWDSFRQSERGEET IEERFEITGTMRRLADQSLPPNFSSLENFRAYVDGFEPNG CIEGKLSQMSKEVNARIEPFLKTTPRPLRLPDGPPCSQRS KFLLMDALKLSIEDPSHEGEGIPLYDAIKCMKTFFGWKEP NIIKPHEKGINPNYLLAWKQVLAELQDIENEEKIPKKKNM KKTSQLKWALGENMAPEKVDFEDCKDVSDLKQYDSDEPEP RSLASWIQSEFNKACELTDSSWIELDEIGEDVAPIEHIAS MRRNYFTAEVSHCRATEYIMKGVYINTALLNASCAAMDDF QLIPMISKCRTKEGRRKTNLYGFIIKGRSHLRNDTDVVNF VSMEFSLTDPRLEPHKWEKYCVLEIGDMLLRTAIGQVSRP MFLYVRTNGTSKIKMKWGMEMRRCLLQSLQQIESMIEAES SVKEKDMTKEFFENKSETWPIGESPKGVEEGSIGKVCRTL LAKSVFNSLYASPQLEGFSAESRRLLLIVQALRDNLEPGT FDLGGLYEAIEECLINDPWVLLNASWFNSFLTHALR H:  MDVNPTLLFLKVPAQNAISTTFPYTGDPPTGYTMDTVNRT HQYSEKGKWTTNTETGAPQLNPIDGPLPDNHEPSGYAQTD CVLEAMAFLEESHPGIFENSCLETMEVVQQTRVDKLTQGR QTYDWTLNRNQPAATALANTIEVFRSNDLTANESGRLIDF LKDVMESMDKEEMEITAHFQRKRTIGKKKQRLNKKSYLIR ALTLNTTPGMQIRGFVYFVETLARSICEKLEQSGLPVGGN EKKAKLANVVRKMMTNSQDTELSFTITGDNTKWNENQNPR MFLAMITYITRNQPDWFRNVLSIAPIMFSNKMARLANIDL KYFNESTRKKIEKIRPLLIDGTASLSPGMMMGMFNMLSTV LGVSILNLGQKRYTKTTYWWDGLQSSDDFALIVNAPNHEG IQAGVDRFYRTCKLVGINMSKKKSYINRTGTFEFTSFFYR YGFVANFSMELPSFGVSGINESADMSIGVTVIKNNMINND LGPATAQMALQLFIKDYRYTYRCHRGDTQIQTRRSFELKK LWEQTRSKAGLLVSDGGPNLYNIRNLHIPEVCLKWELMDE DYQGRLCNPLNPFVSHKEIESANNASMEYDAVATTHSWIP KDEQMYQKCCNLFEKFFPSSSYRRPVGISSMVEAMVSRAR IDARIDFESGRIKKEEFAEIMKICSTIEELRRQ I:  MERIKELRDLMSQSRTREILTKTTVDHIAIIKKYTSGRQE KNPALRMKWMMAMKYPITADKRIMEMIPERNEQGQTLWSD RVMVSSLAVTWWNRNGPTTSTVHYPKVYKTYFEKVERLKH GTFGPVHFRNQVKIRRRVDVNPGHADLSAKEAQDVIMEVV FPNEVGARILTLTITKEKKEELQDCKIAPLMVAYMLEREL VRKTRFLPVAGGTSSVYIEVLHLTQGTCWEQMYTPGGEVR NDDVDQSLIIAARNIVRRATVSTDPLASLLEMCHSTQIGG IRMVDILRQNPTEEQAVDICKAAMGLRISSSFSFGGFTFK RTSGSSVKKEEEVLTGNLQTLKIRVHEGYEEFTMVGRRAT AILRKATRRLIQLIVSGRDEQSIAEAIIVAMVFSQEDCMI KAVRGDLNFVNRANQRLNPMHQLLRHFQKDAKVLFQNWGI EPIDNVMGMIGILPDMTPSTEMSLRGVRVSKMGVDEYSST ERVVVSIDRFLRVRDQRGNVLLSPEEVSETQGTERLTITY SSSMMWSVLVNTYQWVIRNWETVKIQWSQDPTMLYNKMEF EPFQSLIPKAARGQYSGFVRTLFQQMRDVVGTFDTVQIIK LLPFTAAPPEQSRMQFSSLTVNVRGSGMRILVRGNSPVFN YNKATKRLTVLGKDAGALGFLILGKEDKRYGPALSINELS NLAKGEKANVLIGQGDVVLVMKRKRDSSILTDSQTATKRI RM J:  MEDFVRQCFNPMIVELAEKAMKEYGEDPKIETNKFAAICT HLEVCFMYSDFHFIDERGESIIVESGDPNALLKHRFEIIE GRDRTMAWTVVNSICNTTGAEKPKFLPDLYDYKENRFIEI GVTRREVHIYYLEKANKIKSEKTHIHIFPFTGEEMATKAD YTLDEESRARIKTRLFTIRQEMASRGLWDSFRQSERGEET IEERFEITGTMRRLADQSLPPNFSSLENFRAYVDGFEPNG CIEGKLSQMSKEVNARIEPFLKTTPRPLRLPDGPPCSQRS KFLLMDALKLSIEDPSHEGEGIPLYDAIKCMKTFFGWKEP NIIKPHEKGINPNYLLAWKQVLAELQDIENEEKIPKKKNM KKTSQLKWALGENMFEDCKDVSDLKQYDSDEPEPRSLASW IQSEFNKACELTDSSWIELDEIGEDVAPIEHIASMRRNYF TAEVSHCRATEYIMKGVYINTALLNASCAAMDDFQLIPMI SKCRTKEGRRKTNLYGFIIKGRSHLRNDTDVVNFVSMEFS LTDPRLEPHKWEKYCVLEIGDMLLRTAIGQVSRPMFLYVR TNGTSKIKMKWGMEMRRCLLQSLQQIESMIEAESSVKEKD MTKEFFENKSETWPIGESPKGVEEGSIGKVCRTLLAKSVF NSLYASPQLEGFSAESRRLLLIVQALRDNLEPGTFDLGGL YEAIEECLINDPWVLLNASWFNSFLTHALR K:  MDVNPTLLFLKVPAQNAISTTFPYTGDPPTGYTMDTVNRT HQYSEKGKWTTNTETGAPQLNPIDGPLPDNHEPSGYAQTD CVLEAMAFLEESHPGIFENSCLETMEVVQQTRVDKLTQGR QTYDWTLNRNQPAATALANTIEVFRSNDLTANESGRLIDF LKDVMESMDKEEMEITAHFGKKKQRLNKKSYLIRALTLNT TPGMQIRGFVYFVETLARSICEKLEQSGLPVGGNEKKAKL ANVVRKMMTNSQDTELSFTITGDNTKWNENQNPRMFLAMI TYITRNQPDWFRNVLSIAPIMFSNKMARLGKGIPAEMLAN IDLKYFNESTRKKIEKIRPLLIDGTASLSPGMMMGMFNML STVLGVSILNLGQKRYTKTTYWWDGLQSSDDFALIVNAPN HEGIQAGVDRFYRTCKLVGINMSKKKSYINRTGTFEFTSF FYRYGFVANFSMELPSFGVSGINESADMSIGVTVIKNNMI NNDLGPATAQMALQLFIKDYRYTYRCHRGDTQIQTRRSFE LKKLWEQTRSKAGLLVSDGGPNLYNIRNLHIPEVCLKWEL MDEDYQGRLCNPLNPFVYDAVATTHSWIPKDEQMYQKCCN LFEKFFPSSSYRRPVGISSMVEAMVSRARIDARIDFESGR IKKEEFAEIMKICSTIEELRRQ L:  MERIKELRDLMSQSRTREILTKTTVDHIAIIKKYTSGRQE KNPALRMKWMMAMKYPITADKRIMEMIPERNEQGQTLWSK TDRVMVSSLAVTWWNRNGPTTSTVHYPKVYKTYFEKVERL KHGTFGPVHFRNQVKIRRRVDVNPGHADLSAKEAQDVIME VVFPNEVGARILTLTITKEKKEELQDCKIAPLMVAYMLER ELVRKTRFLPVAGGTSSVYIEVLHLTQGTCWEQMYTPGGE VRNDDVDQSLIIAARNIVRRATVSTDPLASLLEMCHSTQI GGIRMVDILRQNPTEEQAVDICKAAMGLRISSSFSFGGFT FKRTSGSSVKKEEEVLTGNLQTLKIRVHEGYEEFTMVGRR ATAILRKATRRLIQLIVSGRDEQSIAEAIIVAMVFSQEDC MIKAVRGDLNFVNRANQRLNPMHQLLRHFQKDAKVLFQNW GIEPIDNVMGMIGILPDMTPSTEMSLRGVRVSKMGVDEYS STERVVVSIDRFLRVRDQRGNVLLSPEEVSETQGTERLTI TYSSSMMWEINGPESVLVNTYQWVIRNWETVKIQWSQDPT MLYNKMEFEPFQSLIPKAARGQYSGFVRTLFQQMRDVVGT FDTVQIIKLLPFTAAPPEQSRMQFSSLTVNVRGSGMRILV RGNSPVFNYNKATKRLTVLGKDAGALGFLILGKEDKRYGP ALSINELSNLAKGEKANVLIGQGDVVLVMKRKRDSSILTD SQTATKRIRM Description

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