|
|
eF-site ID
|
6qm7-J |
|
PDB Code
|
6qm7 |
|
Chain
|
J |
|
click to enlarge
|
|
|
Title
|
Leishmania tarentolae proteasome 20S subunit complexed with GSK3494245 |
|
Classification
|
HYDROLASE |
|
Compound
|
Proteasome alpha1 chain |
|
Source
|
ORGANISM_SCIENTIFIC: Leishmania tarentolae; |
|
|
Sequence
|
J: |
SIMAYSGGSVMAMAGKECFVIISDNRLGEQLKTISTEVPK
LHVVNDSIVYGLTGLRTDQQTFANKVQFRTEMYKLREERD
ITGKAFAAMITSMLYEARFGPWFVEPVIGSIDKSTGEVYL
CATDLIGAPCEPEDYVCAGTAAESLHGMCEALWRPGMSPE
ELFEIAAQAMLSACDRDSLSGYGAVAMIVTKDKVTTRLIK
GRKD
|
|
|
Description
|
(1) |
Proteasome alpha1 chain, Proteasome alpha2 chain, Proteasome alpha3 chain, Proteasome alpha4 chain, Proteasome alpha5 chain, Proteasome alpha6 chain, Proteasome alpha7 chain, Proteasome beta1 chain, Proteasome beta2 chain, Proteasome beta3 chain, Proteasome beta4 chain, Proteasome beta5 chain, Proteasome beta6 chain, Proteasome beta7 chain
|
|
Functional site
|
|
|
1)
|
chain |
J |
| residue |
32 |
| type |
|
| sequence |
L
|
| description |
binding site for residue J6E Z 4000
|
| source |
: AC2
|
|
|
2)
|
chain |
J |
| residue |
12-59 |
| type |
prosite |
| sequence |
MAMAGKECFVIISDNRLGEQLKTISTEVPKLHVVNDSIVY
GLTGLRTD
|
| description |
PROTEASOME_BETA_1 Proteasome beta-type subunits signature. VGVvYrdGVVLGADtrategsivadkrcr.KihymapnimccgaGtsAD
|
| source |
prosite : PS00854
|
|
|
|