eF-site ID 6qib-A PDB Code 6qib Chain A click to enlarge Title The crystal structure of Pol2CORE in complex with DNA and an incoming nucleotide, carrying an Fe-S cluster Classification DNA BINDING PROTEIN Compound DNA polymerase epsilon catalytic subunit A Source (6QIB) Sequence A:  ALSAQQLLNASKIDDIDSMMGFERYVPPQYNGRFDAKDID QIPGRVGWLTNMHATLVSQEQGISGVDFYFLDEEGGSFKS TVVYDPYFFIACNDESRVNDVEELVKKYLESCLKSLQIIR KEDLTMDNHLLGLQKTLIKLSFVNSNQLFEARKLLRPILQ DNANNNVQRNIYNVVDAKHLIEDIREYDVPYHVRVSIDKD IRVGKWYKVTQQGFIEDTRKIAFADPVVMAFAIATTKPPL KFPDSAVDQIMMISYMIDGEGFLITNREIISEDIEDFEYT PKPEYPGFFTIFNENDEVALLQRFFEHIRDVRPTVISTFN GDFFDWPFIHNRSKIHGLDMFDEIGFAPDAEGEYKSSYCS HMDCFRWVKRDSYLPQGSQGLKAVTQSKLGYNPIELDPEL MTPYAFEKPQHLSEYSVSDAVATYYLYMKYVHPFIFSLCT IIPLNPDETLRKGTGTLCEMLLMVQAYQHNILLPNKHTDP IERFYDGHLLESETYVGGHVESLEAGVFRSDLKNEFKIDP SAIDELLQELPEALKFSVEVENKSSVDKVTNFEEIKNQIT QKLLELKENNIRNELPLIYHVDVASMYPNIMTTNRLQPDS IKAERDCASCDFNRPGKTCARKLKWAWRGEFFPSKMDEYN MIKRALQNETFPNKKKKVLTFDELSYADQVIHIKKRLTEY SRKVYHRVKVSEIVEREAIVCQRENPFYVDTVKSFRDRRY EFKGLAKTWKGNLSKIDPSDKHARDEAKKMIVLYDSLQLA HKVILNSFYGYVMRKGSRWYSMEMAGITCLTGATIIQMAR ALVERVGRPLELDTDGIWCILPKSFPETYFFTLENGKKLY LSYPCSMLNYRVHQKFTNHQYQELKDPLNYIYETHSENTI FFEVDGPYKAMILPSSKEEGKGIKKRYAVFNEDGSLAELK GFELKRRGELQLIKNFQSDIFKVFLEGDTLEGCYSAVASV CNRWLDVLDSHGLMLEDEDLVSLICENRSMSKTLKEYEGQ KSTSITTARRLGDFLGEDMVKDKGLQCKYIISSKPFNAPV TERAIPVAIFSADIPIKRSFLRRWTLDPSLEDLDIRTIID WGYYRERLGSAIQKIITIPAALQGVSNPVPRVEHPDWLKR KIA Description Functional site 1) chain A residue 665 type sequence C description binding site for residue SF4 A 1201 source : AC1 2) chain A residue 668 type sequence C description binding site for residue SF4 A 1201 source : AC1 3) chain A residue 677 type sequence C description binding site for residue SF4 A 1201 source : AC1 4) chain A residue 678 type sequence A description binding site for residue SF4 A 1201 source : AC1 5) chain A residue 763 type sequence C description binding site for residue SF4 A 1201 source : AC1 6) chain A residue 765 type sequence R description binding site for residue SF4 A 1201 source : AC1 7) chain A residue 640 type sequence D description binding site for residue DTP A 1202 source : AC2 8) chain A residue 641 type sequence V description binding site for residue DTP A 1202 source : AC2 9) chain A residue 642 type sequence A description binding site for residue DTP A 1202 source : AC2 10) chain A residue 643 type sequence S description binding site for residue DTP A 1202 source : AC2 11) chain A residue 644 type sequence M description binding site for residue DTP A 1202 source : AC2 12) chain A residue 645 type sequence Y description binding site for residue DTP A 1202 source : AC2 13) chain A residue 781 type sequence R description binding site for residue DTP A 1202 source : AC2 14) chain A residue 785 type sequence K description binding site for residue DTP A 1202 source : AC2 15) chain A residue 824 type sequence K description binding site for residue DTP A 1202 source : AC2 16) chain A residue 828 type sequence N description binding site for residue DTP A 1202 source : AC2 17) chain A residue 877 type sequence D description binding site for residue DTP A 1202 source : AC2 18) chain A residue 640 type sequence D description binding site for residue CA A 1203 source : AC3 19) chain A residue 641 type sequence V description binding site for residue CA A 1203 source : AC3 20) chain A residue 877 type sequence D description binding site for residue CA A 1203 source : AC3

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