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eF-site ID
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6qhd-B |
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PDB Code
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6qhd |
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Chain
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B |
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click to enlarge
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Title
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Lysine acetylated and tyrosine phosphorylated STAT3 in a complex with DNA |
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Classification
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TRANSCRIPTION |
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Compound
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Signal transducer and activator of transcription 3 |
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Source
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(6QHD) |
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Sequence
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B: |
VVTEKQQMLEQHLQDVRKRVQDLEQKMKVVENLQDDFDFN
YKTLKSQGSVTRQKMQQLEQMLTALDQMRRSIVSELAGLL
SAMEYVQKTLTDEELADWKRRQQIACIGGPPNICLDRLEN
WITSLAESQLQTRQQIKKLEELQQKVSYKGDPIVQHRPML
EERIVELFRNLMKSAFVVERQPCMPMHPDRPLVIKTGVQF
TTKVRLLVKFPELNYQLKIKVCIDKDSGDVAALRGSRKFN
ILGTNTKVMNMEESNNGSLSAEFKHLTLREQRASLIVTEE
LHLITFETEVYHQGLKIDLETHSLPVVVISNICQMPNAWA
SILWYNMLTNNPKNVNFFTKPPIGTWDQVAEVLSWQFSST
TKRGLSIEQLTTLAEKLLGPYSGCQITWAKFCKENMAGKG
FSFWVWLDNIIDLVKKYILALWNEGYIMGFISKERERAIL
STKPPGTFLLRFSESSKEGGVTFTWVETQIQSVEPYTKQQ
LNNMSFAEIIMGYKIILVSPLVYLYPDIPKEEAFGXYCRA
PXLKTKFICVTP
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Description
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Functional site
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|
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1)
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chain |
B |
| residue |
714 |
| type |
MOD_RES |
| sequence |
T
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| description |
Phosphothreonine => ECO:0007744|PubMed:24275569
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| source |
Swiss-Prot : SWS_FT_FI5
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2)
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chain |
B |
| residue |
685 |
| type |
MOD_RES |
| sequence |
X
|
| description |
N6-acetyllysine; alternate => ECO:0000269|PubMed:15653507, ECO:0000269|PubMed:28065600
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| source |
Swiss-Prot : SWS_FT_FI2
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3)
|
chain |
B |
| residue |
601 |
| type |
MOD_RES |
| sequence |
K
|
| description |
N6-acetyllysine; alternate => ECO:0000269|PubMed:28065600
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| source |
Swiss-Prot : SWS_FT_FI1
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|
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4)
|
chain |
B |
| residue |
615 |
| type |
MOD_RES |
| sequence |
K
|
| description |
N6-acetyllysine; alternate => ECO:0000269|PubMed:28065600
|
| source |
Swiss-Prot : SWS_FT_FI1
|
|
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5)
|
chain |
B |
| residue |
705 |
| type |
MOD_RES |
| sequence |
X
|
| description |
Phosphotyrosine; by FER and PTK6 => ECO:0000269|PubMed:12763138, ECO:0000269|PubMed:16568091, ECO:0000269|PubMed:21135090, ECO:0000269|PubMed:22306293, ECO:0000269|PubMed:26293184, ECO:0000269|PubMed:31899195, ECO:0000269|PubMed:32929201, ECO:0007744|PubMed:15592455, ECO:0007744|PubMed:24275569
|
| source |
Swiss-Prot : SWS_FT_FI3
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|
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6)
|
chain |
B |
| residue |
707 |
| type |
MOD_RES |
| sequence |
K
|
| description |
N6-acetyllysine => ECO:0000269|PubMed:28065600
|
| source |
Swiss-Prot : SWS_FT_FI4
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