|
eF-site ID
|
6qc8-.S1 |
PDB Code
|
6qc8 |
Chain
|
S1 |
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Title
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Ovine respiratory complex I FRC open class 2 |
Classification
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ELECTRON TRANSPORT |
Compound
|
NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial |
Source
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ORGANISM_COMMON: Sheep; ORGANISM_SCIENTIFIC: Ovis aries; |
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Sequence
|
S1: |
SNLIEVFVDGQSVMVEPGTTVLQACEKVGMQIPRFCYHER
LSVAGNCRMCLVEIEKAPKVVAACAMPVMKGWNILTNSEK
TKKAREGVMEFLLANHPLDCPICDQGGECDLQDQSMMFGS
DRSRFLEGKRAVEDKNIGPLVKTIMTRCIQCTRCIRFASE
IAGVDDLGTTGRGNDMQVGTYIEKMFMSELSGNIIDICPV
GALTSKPYAFTARPWETRKTESIDVMDAVGSNIVVSTRTG
EVMRILPRMHEDINEEWISDKTRFAYDGLKRQRLTEPMVR
NEKGLLTHTTWEDALSRVAGMLQSCQGNDVAAIAGGLVDA
EALIALKDLLNRVDSDTLCTEEVFPTAGAGTDLRSNYLLN
TTIAGVEEADVVLLVGTNPRFEAPLFNARIRKSWLHNDLK
VALIGSPVDLTYRYDHLGDSPKILQDIASGSHPFSQVLQE
AKKPMVVLGSSALQRNDGAAILAAVSNIAQKIRTSSGVTG
DWKVMNILHRIASQVAALDLGYKPGVEAIRKNPPKMLFLL
GADGGCVTRQDLPKDCFIVYQGHHGDVGAPIADVILPGAA
YTEKSATYVNTEGRAQQTKVAVMPPGLAREDWKIIRALSE
IAGMTLPYDTLDQVRNRLEEVSPNLVRYDDVEGANYFQQA
SELSKLVNQQLLADPLVPPQLTIKDFYMTDSISRASQTMA
KCVKAVTE
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Description
|
(1) |
NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial (E.C.1.6.99.3,7.1.1.2), NDUFV2, NADH:ubiquinone oxidoreductase core subunit S1, NADH:ubiquinone oxidoreductase core subunit S2, NADH:ubiquinone oxidoreductase core subunit S3, NADH:ubiquinone oxidoreductase core subunit S7, NADH dehydrogenase [ubiquinone] iron-sulfur protein 8, mitochondrial, NADH:ubiquinone oxidoreductase subunit V3, NADH dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrial, NADH:ubiquinone oxidoreductase subunit S4, NADH:ubiquinone oxidoreductase subunit A9, NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2, NDUFA5, NADH:ubiquinone oxidoreductase subunit A6, NDUFA7, NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12, Acyl carrier protein, NADH-ubiquinone oxidoreductase chain 3 (E.C.7.1.1.2), NADH-ubiquinone oxidoreductase chain 1 (E.C.7.1.1.2), NADH-ubiquinone oxidoreductase chain 6 (E.C.7.1.1.2), NADH-ubiquinone oxidoreductase chain 4L (E.C.7.1.1.2), NADH-ubiquinone oxidoreductase chain 5 (E.C.7.1.1.2), NADH-ubiquinone oxidoreductase chain 4 (E.C.7.1.1.2), NADH-ubiquinone oxidoreductase chain 2 (E.C.7.1.1.2), NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 11, NADH:ubiquinone oxidoreductase subunit B5, NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8, NADH:ubiquinone oxidoreductase subunit B10, NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial, NADH:ubiquinone oxidoreductase subunit S5, NADH:ubiquinone oxidoreductase subunit A3, NADH:ubiquinone oxidoreductase subunit B3, NADH dehydrogenase [ubiquinone] 1 subunit C2, NADH:ubiquinone oxidoreductase subunit B4, NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13, NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 6, NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 7, NADH:ubiquinone oxidoreductase subunit B9, NADH:ubiquinone oxidoreductase subunit B2, NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8, mitochondrial, NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 11, mitochondrial, NADH dehydrogenase [ubiquinone] 1 subunit C1, mitochondrial, Uncharacterized protein, NADH dehydrogenase 1 alpha subcomplex
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Functional site
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|
1)
|
chain |
S1 |
residue |
101 |
type |
|
sequence |
H
|
description |
binding site for residue SF4 S1 801
|
source |
: AC4
|
|
2)
|
chain |
S1 |
residue |
104 |
type |
|
sequence |
D
|
description |
binding site for residue SF4 S1 801
|
source |
: AC4
|
|
3)
|
chain |
S1 |
residue |
105 |
type |
|
sequence |
C
|
description |
binding site for residue SF4 S1 801
|
source |
: AC4
|
|
4)
|
chain |
S1 |
residue |
108 |
type |
|
sequence |
C
|
description |
binding site for residue SF4 S1 801
|
source |
: AC4
|
|
5)
|
chain |
S1 |
residue |
110 |
type |
|
sequence |
Q
|
description |
binding site for residue SF4 S1 801
|
source |
: AC4
|
|
6)
|
chain |
S1 |
residue |
114 |
type |
|
sequence |
C
|
description |
binding site for residue SF4 S1 801
|
source |
: AC4
|
|
7)
|
chain |
S1 |
residue |
117 |
type |
|
sequence |
Q
|
description |
binding site for residue SF4 S1 801
|
source |
: AC4
|
|
8)
|
chain |
S1 |
residue |
152 |
type |
|
sequence |
R
|
description |
binding site for residue SF4 S1 801
|
source |
: AC4
|
|
9)
|
chain |
S1 |
residue |
205 |
type |
|
sequence |
V
|
description |
binding site for residue SF4 S1 801
|
source |
: AC4
|
|
10)
|
chain |
S1 |
residue |
206 |
type |
|
sequence |
G
|
description |
binding site for residue SF4 S1 801
|
source |
: AC4
|
|
11)
|
chain |
S1 |
residue |
153 |
type |
|
sequence |
C
|
description |
binding site for residue SF4 S1 802
|
source |
: AC5
|
|
12)
|
chain |
S1 |
residue |
154 |
type |
|
sequence |
I
|
description |
binding site for residue SF4 S1 802
|
source |
: AC5
|
|
13)
|
chain |
S1 |
residue |
156 |
type |
|
sequence |
C
|
description |
binding site for residue SF4 S1 802
|
source |
: AC5
|
|
14)
|
chain |
S1 |
residue |
157 |
type |
|
sequence |
T
|
description |
binding site for residue SF4 S1 802
|
source |
: AC5
|
|
15)
|
chain |
S1 |
residue |
159 |
type |
|
sequence |
C
|
description |
binding site for residue SF4 S1 802
|
source |
: AC5
|
|
16)
|
chain |
S1 |
residue |
203 |
type |
|
sequence |
C
|
description |
binding site for residue SF4 S1 802
|
source |
: AC5
|
|
17)
|
chain |
S1 |
residue |
205 |
type |
|
sequence |
V
|
description |
binding site for residue SF4 S1 802
|
source |
: AC5
|
|
18)
|
chain |
S1 |
residue |
41 |
type |
|
sequence |
C
|
description |
binding site for residue FES S1 803
|
source |
: AC6
|
|
19)
|
chain |
S1 |
residue |
42 |
type |
|
sequence |
Y
|
description |
binding site for residue FES S1 803
|
source |
: AC6
|
|
20)
|
chain |
S1 |
residue |
50 |
type |
|
sequence |
G
|
description |
binding site for residue FES S1 803
|
source |
: AC6
|
|
21)
|
chain |
S1 |
residue |
52 |
type |
|
sequence |
C
|
description |
binding site for residue FES S1 803
|
source |
: AC6
|
|
22)
|
chain |
S1 |
residue |
53 |
type |
|
sequence |
R
|
description |
binding site for residue FES S1 803
|
source |
: AC6
|
|
23)
|
chain |
S1 |
residue |
55 |
type |
|
sequence |
C
|
description |
binding site for residue FES S1 803
|
source |
: AC6
|
|
24)
|
chain |
S1 |
residue |
69 |
type |
|
sequence |
C
|
description |
binding site for residue FES S1 803
|
source |
: AC6
|
|
25)
|
chain |
S1 |
residue |
38-55 |
type |
prosite |
sequence |
PRFCYHERLSVAGNCRMC
|
description |
COMPLEX1_75K_1 Respiratory-chain NADH dehydrogenase 75 Kd subunit signature 1. PrfCYherlsvaGnCRmC
|
source |
prosite : PS00641
|
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26)
|
chain |
S1 |
residue |
105-117 |
type |
prosite |
sequence |
CPICDQGGECDLQ
|
description |
COMPLEX1_75K_2 Respiratory-chain NADH dehydrogenase 75 Kd subunit signature 2. CPiCDqGGeCdLQ
|
source |
prosite : PS00642
|
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27)
|
chain |
S1 |
residue |
152-162 |
type |
prosite |
sequence |
RCIQCTRCIRF
|
description |
COMPLEX1_75K_3 Respiratory-chain NADH dehydrogenase 75 Kd subunit signature 3. RCIqCtRCIrF
|
source |
prosite : PS00643
|
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