eF-site ID 6q8a-A PDB Code 6q8a Chain A click to enlarge Title Neisseria gonorrhoeae Leucyl-tRNA Synthetase in Complex with 5'-O-(N-(L-Leucyl)-Sulfamoyl)Cytidine Classification LIGASE Compound Leucine--tRNA ligase Source (SYL_NEIG2) Sequence A:  MQEHYQPAAIEPAAQKKWDDARISNVSEDASKPKYYCLSM FPYPSGKLHMGHVRNYTIGDVLSRFKLLNGFNVMQPMGWD AFGMPAENAAMKNNVAPAAWTYDNIEYMKTQLKSLGFAVD WEREVATCKPEYYRWEQWLFTKLFEKGIVYRKNGTVNWDP VDQTVLANEQVIDGRGWRSGALIEKREIPMYYFKITDYAE ELLNDLDKLEHWPEQVKTMQRNWIGKSRGMTVRFAVSDDS KQGLEGDYAKFLQVYTTRPDTLMGATYVAVAAEHPLATAA AADKPELQAFIAECKAGSVAEADMATMEKKGVPTGRYVVN PLNGDKLEVWIANYVLWGYGDGAVMAVPAHDERDFEFAAK YNLPKKQVIAVGDNAFDANRWQEWYGDKENGVLVNSGDLD GLDFQTAFDAVAAKLQSQGAGEPKTQYRLRDWGISRQRYW GCPIPIVHCEKCGNVPVPADQLPVVLPENVVPDGMGSPLA KMPEFYETSCPCCGGAAKRETDTMDTFIESSWYFFRYMSP KFSDGMVSAESAKYWGAVDQYIGGIEHAILHLLYARFFTK LMRDEGLVNVDEPFERLLTQGMVVCETYYRENDKGGKDWI NPADVELTGLPVVISGTEKMSKSKNNGVDPQELINAYGAD TARLFMMFAAPPEQSLEWSDSGVEGAHRFLRRLWRTVYEY LKQGGAVKAFAGNQDGLSKELKDLRHKLHSTTAKVSDDYG RRQQFNTAIAAVMELLNQYDKTDTGSEQGRAVAQEVLEAA VRLLWPIVPHICETLWSELNGAKLWEAGWPTVDEAALVKS EIITVAADIIVVPGRLVNIV Description Functional site 1) chain A residue 40 type sequence M description binding site for residue HQ5 A 901 source : AC1 2) chain A residue 41 type sequence F description binding site for residue HQ5 A 901 source : AC1 3) chain A residue 42 type sequence P description binding site for residue HQ5 A 901 source : AC1 4) chain A residue 43 type sequence Y description binding site for residue HQ5 A 901 source : AC1 5) chain A residue 49 type sequence H description binding site for residue HQ5 A 901 source : AC1 6) chain A residue 51 type sequence G description binding site for residue HQ5 A 901 source : AC1 7) chain A residue 52 type sequence H description binding site for residue HQ5 A 901 source : AC1 8) chain A residue 55 type sequence N description binding site for residue HQ5 A 901 source : AC1 9) chain A residue 56 type sequence Y description binding site for residue HQ5 A 901 source : AC1 10) chain A residue 80 type sequence D description binding site for residue HQ5 A 901 source : AC1 11) chain A residue 510 type sequence S description binding site for residue HQ5 A 901 source : AC1 12) chain A residue 513 type sequence Y description binding site for residue HQ5 A 901 source : AC1 13) chain A residue 541 type sequence Y description binding site for residue HQ5 A 901 source : AC1 14) chain A residue 543 type sequence G description binding site for residue HQ5 A 901 source : AC1 15) chain A residue 544 type sequence G description binding site for residue HQ5 A 901 source : AC1 16) chain A residue 546 type sequence E description binding site for residue HQ5 A 901 source : AC1 17) chain A residue 547 type sequence H description binding site for residue HQ5 A 901 source : AC1 18) chain A residue 551 type sequence H description binding site for residue HQ5 A 901 source : AC1 19) chain A residue 580 type sequence Q description binding site for residue HQ5 A 901 source : AC1 20) chain A residue 449 type sequence C description binding site for residue ZN A 902 source : AC2 21) chain A residue 452 type sequence C description binding site for residue ZN A 902 source : AC2 22) chain A residue 490 type sequence C description binding site for residue ZN A 902 source : AC2 23) chain A residue 493 type sequence C description binding site for residue ZN A 902 source : AC2 24) chain A residue 42-53 type prosite sequence PYPSGKLHMGHV description AA_TRNA_LIGASE_I Aminoacyl-transfer RNA synthetases class-I signature. PypSGkLHMGHV source prosite : PS00178 25) chain A residue 637 type BINDING sequence K description BINDING => ECO:0000255|HAMAP-Rule:MF_00049 source Swiss-Prot : SWS_FT_FI1

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