eF-site ID 6q8a-A
PDB Code 6q8a
Chain A

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Title Neisseria gonorrhoeae Leucyl-tRNA Synthetase in Complex with 5'-O-(N-(L-Leucyl)-Sulfamoyl)Cytidine
Classification LIGASE
Compound Leucine--tRNA ligase
Source (SYL_NEIG2)
Sequence A:  MQEHYQPAAIEPAAQKKWDDARISNVSEDASKPKYYCLSM
FPYPSGKLHMGHVRNYTIGDVLSRFKLLNGFNVMQPMGWD
AFGMPAENAAMKNNVAPAAWTYDNIEYMKTQLKSLGFAVD
WEREVATCKPEYYRWEQWLFTKLFEKGIVYRKNGTVNWDP
VDQTVLANEQVIDGRGWRSGALIEKREIPMYYFKITDYAE
ELLNDLDKLEHWPEQVKTMQRNWIGKSRGMTVRFAVSDDS
KQGLEGDYAKFLQVYTTRPDTLMGATYVAVAAEHPLATAA
AADKPELQAFIAECKAGSVAEADMATMEKKGVPTGRYVVN
PLNGDKLEVWIANYVLWGYGDGAVMAVPAHDERDFEFAAK
YNLPKKQVIAVGDNAFDANRWQEWYGDKENGVLVNSGDLD
GLDFQTAFDAVAAKLQSQGAGEPKTQYRLRDWGISRQRYW
GCPIPIVHCEKCGNVPVPADQLPVVLPENVVPDGMGSPLA
KMPEFYETSCPCCGGAAKRETDTMDTFIESSWYFFRYMSP
KFSDGMVSAESAKYWGAVDQYIGGIEHAILHLLYARFFTK
LMRDEGLVNVDEPFERLLTQGMVVCETYYRENDKGGKDWI
NPADVELTGLPVVISGTEKMSKSKNNGVDPQELINAYGAD
TARLFMMFAAPPEQSLEWSDSGVEGAHRFLRRLWRTVYEY
LKQGGAVKAFAGNQDGLSKELKDLRHKLHSTTAKVSDDYG
RRQQFNTAIAAVMELLNQYDKTDTGSEQGRAVAQEVLEAA
VRLLWPIVPHICETLWSELNGAKLWEAGWPTVDEAALVKS
EIITVAADIIVVPGRLVNIV
Description


Functional site

1) chain A
residue 40
type
sequence M
description binding site for residue HQ5 A 901
source : AC1

2) chain A
residue 41
type
sequence F
description binding site for residue HQ5 A 901
source : AC1

3) chain A
residue 42
type
sequence P
description binding site for residue HQ5 A 901
source : AC1

4) chain A
residue 43
type
sequence Y
description binding site for residue HQ5 A 901
source : AC1

5) chain A
residue 49
type
sequence H
description binding site for residue HQ5 A 901
source : AC1

6) chain A
residue 51
type
sequence G
description binding site for residue HQ5 A 901
source : AC1

7) chain A
residue 52
type
sequence H
description binding site for residue HQ5 A 901
source : AC1

8) chain A
residue 55
type
sequence N
description binding site for residue HQ5 A 901
source : AC1

9) chain A
residue 56
type
sequence Y
description binding site for residue HQ5 A 901
source : AC1

10) chain A
residue 80
type
sequence D
description binding site for residue HQ5 A 901
source : AC1

11) chain A
residue 510
type
sequence S
description binding site for residue HQ5 A 901
source : AC1

12) chain A
residue 513
type
sequence Y
description binding site for residue HQ5 A 901
source : AC1

13) chain A
residue 541
type
sequence Y
description binding site for residue HQ5 A 901
source : AC1

14) chain A
residue 543
type
sequence G
description binding site for residue HQ5 A 901
source : AC1

15) chain A
residue 544
type
sequence G
description binding site for residue HQ5 A 901
source : AC1

16) chain A
residue 546
type
sequence E
description binding site for residue HQ5 A 901
source : AC1

17) chain A
residue 547
type
sequence H
description binding site for residue HQ5 A 901
source : AC1

18) chain A
residue 551
type
sequence H
description binding site for residue HQ5 A 901
source : AC1

19) chain A
residue 580
type
sequence Q
description binding site for residue HQ5 A 901
source : AC1

20) chain A
residue 449
type
sequence C
description binding site for residue ZN A 902
source : AC2

21) chain A
residue 452
type
sequence C
description binding site for residue ZN A 902
source : AC2

22) chain A
residue 490
type
sequence C
description binding site for residue ZN A 902
source : AC2

23) chain A
residue 493
type
sequence C
description binding site for residue ZN A 902
source : AC2

24) chain A
residue 42-53
type prosite
sequence PYPSGKLHMGHV
description AA_TRNA_LIGASE_I Aminoacyl-transfer RNA synthetases class-I signature. PypSGkLHMGHV
source prosite : PS00178

25) chain A
residue 637
type BINDING
sequence K
description BINDING => ECO:0000255|HAMAP-Rule:MF_00049
source Swiss-Prot : SWS_FT_FI1


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