eF-site ID 6q5b-B PDB Code 6q5b Chain B click to enlarge Title OXA-48_P68A-AVI. Evolutionary trade-offs of OXA-48 mediated ceftazidime-avibactam resistance Classification ANTIBIOTIC Compound Beta-lactamase Source (Q6XEC0_KLEPN) Sequence B:  EWQENKSWNAHFTEHKSQGVVVLWNENKQQGFTNNLKRAN QAFLAASTFXIPNSLIALDLGVVKDEHQVFKWDGQTRDIA TWNRDHNLITAMKYSVVPVYQEFARQIGEARMSKMLHAFD YGNEDISGNVDSFWLDGGIRISATEQISFLRKLYHNKLHV SERSQRIVKQAMLTEANGDYIIRAKTGYSTRIEPKIGWWV GWVELDDNVWFFAMNMDMPTSDGLGLRQAITKEVLKQEKI IP Description Functional site 1) chain B residue 206 type sequence R description binding site for residue CL A 303 source : AC3 2) chain B residue 69 type sequence A description binding site for residue NXL B 301 source : AC5 3) chain B residue 70 type sequence S description binding site for residue NXL B 301 source : AC5 4) chain B residue 118 type sequence S description binding site for residue NXL B 301 source : AC5 5) chain B residue 120 type sequence V description binding site for residue NXL B 301 source : AC5 6) chain B residue 208 type sequence K description binding site for residue NXL B 301 source : AC5 7) chain B residue 209 type sequence T description binding site for residue NXL B 301 source : AC5 8) chain B residue 210 type sequence G description binding site for residue NXL B 301 source : AC5 9) chain B residue 211 type sequence Y description binding site for residue NXL B 301 source : AC5 10) chain B residue 250 type sequence R description binding site for residue NXL B 301 source : AC5 11) chain B residue 184 type sequence S description binding site for residue CL B 302 source : AC6 12) chain B residue 186 type sequence R description binding site for residue CL B 302 source : AC6 13) chain B residue 187 type sequence S description binding site for residue CL B 302 source : AC6 14) chain B residue 68-78 type prosite sequence AASTFXIPNSL description BETA_LACTAMASE_D Beta-lactamase class-D active site. AaSTFKIPnSL source prosite : PS00337

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