eF-site ID 6pbf-C
PDB Code 6pbf
Chain C

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Title ZINC9155420-bound TRPV5 in nanodiscs
Classification TRANSPORT PROTEIN
Compound Transient receptor potential cation channel subfamily V member 5
Source (TRPV5_RABIT)
Sequence C:  WEQYRDRVNMLQQERIRDSPLLQAAKENDLRLLKILLFQQ
RGAVGETALHVAALYDNLEAATLLMEAAPELAKEPALCEP
FVGQTALHIAVMNQNLNLVRALLARGASVSARATGAAFRR
SPHNLIYYGEHPLSFAACVGSEEIVRLLIEHGADIRAQDS
LGNTVLHILILQPNKTFACQMYNLLLSYDEQSLELVPNHQ
GLTPFKLAGVEGNTVMFQHLMQKRKHVQWTCGPLTSTLYD
LTEIDSWGEELSFLELVVSSKKREARQILEQTPVKELVSF
KWKKYGRPYFCVLASLYILYMICFTTCCIYRPLKLRDDNR
TDPRDITILQQKLLQEAYVTHQDNIRLVGELVTVTGAVII
LLLEIPDIFRVGASRYFGQTILGGPFHVIIITYASLVLLT
MVMRLTNMNGEVVPLSFALVLGWCSVMYFARGFQMLGPFT
IMIQKMIFGDLMRFCWLMAVVILGFASAFHITFQTEDPNN
LGEFSDYPTALFSTFELFLTIIDGPANYSVDLPFMYCITY
AAFAIIATLLMLNLFIAMMGDTHWRVAQERDELWRAQVVA
TTVMLERKMPRFLWPRSGICGYEYGLGDRWFLRVENHH
Description


Functional site
1) chain C
residue 564
type
sequence I
description binding site for residue O6V A 1001
source : AC1
2) chain C
residue 491
type
sequence M
description binding site for residue O6V C 1001
source : AC4
3) chain C
residue 494
type
sequence C
description binding site for residue O6V C 1001
source : AC4
4) chain C
residue 409-419
type TOPO_DOM
sequence RVGASRYFGQT
description Cytoplasmic => ECO:0000269|PubMed:29323279
source Swiss-Prot : SWS_FT_FI1
5) chain C
residue 470-492
type TOPO_DOM
sequence RGFQMLGPFTIMIQKMIFGDLMR
description Cytoplasmic => ECO:0000269|PubMed:29323279
source Swiss-Prot : SWS_FT_FI1
6) chain C
residue 557-577
type TRANSMEM
sequence ITYAAFAIIATLLMLNLFIAM
description Helical => ECO:0000269|PubMed:29323279
source Swiss-Prot : SWS_FT_FI2
7) chain C
residue 328-348
type TRANSMEM
sequence YFCVLASLYILYMICFTTCCI
description Helical => ECO:0000269|PubMed:29323279
source Swiss-Prot : SWS_FT_FI2
8) chain C
residue 386-408
type TRANSMEM
sequence LVGELVTVTGAVIILLLEIPDIF
description Helical => ECO:0000269|PubMed:29323279
source Swiss-Prot : SWS_FT_FI2
9) chain C
residue 420-442
type TRANSMEM
sequence ILGGPFHVIIITYASLVLLTMVM
description Helical => ECO:0000269|PubMed:29323279
source Swiss-Prot : SWS_FT_FI2
10) chain C
residue 449-469
type TRANSMEM
sequence GEVVPLSFALVLGWCSVMYFA
description Helical => ECO:0000269|PubMed:29323279
source Swiss-Prot : SWS_FT_FI2
11) chain C
residue 493-513
type TRANSMEM
sequence FCWLMAVVILGFASAFHITFQ
description Helical => ECO:0000269|PubMed:29323279
source Swiss-Prot : SWS_FT_FI2
12) chain C
residue 349-385
type TOPO_DOM
sequence YRPLKLRDDNRTDPRDITILQQKLLQEAYVTHQDNIR
description Extracellular => ECO:0000269|PubMed:29323279
source Swiss-Prot : SWS_FT_FI3
13) chain C
residue 443-448
type TOPO_DOM
sequence RLTNMN
description Extracellular => ECO:0000269|PubMed:29323279
source Swiss-Prot : SWS_FT_FI3
14) chain C
residue 524-544
type INTRAMEM
sequence SDYPTALFSTFELFLTIIDGP
description Pore-forming => ECO:0000269|PubMed:29323279
source Swiss-Prot : SWS_FT_FI4
15) chain C
residue 542
type BINDING
sequence D
description BINDING => ECO:0000269|PubMed:29323279
source Swiss-Prot : SWS_FT_FI5
16) chain C
residue 358
type CARBOHYD
sequence N
description N-linked (GlcNAc...) asparagine => ECO:0000255
source Swiss-Prot : SWS_FT_FI8

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