eF-site ID 6p5v-A PDB Code 6p5v Chain A click to enlarge Title Structure of DCN1 bound to N-((4S,5S)-7-ethyl-4-(4-fluorophenyl)-3-methyl-6-oxo-1-phenyl-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-b]pyridin-5-yl)-3-methylbenzamide Classification LIGASE Compound Lysozyme,DCN1-like protein 1 fusion Source (DCNL1_HUMAN) Sequence A:  HSQDLENLYFQGSMNIFEMLRIDEGLRLKIYKDTEGYYTI GIGHLLTKSPSLNAAKSELDKAIGRNTNGVITKDEAEKLF NQDVDAAVRGILRNAKLKPVYDSLDAVRRAALINMVFQMG ETGVAGFTNSLRMLQQKRWDEAAVNLAKSRWYNQTPNRTK RVITTFRTGTWDAYKNLRKKLEQLYNRYKDPQDENKIGID GIQQFCDDLALDPASISVLIIAWKFRAATQCEFSKQEFMD GMTELGCDSIEKLKAQIPKMEQELKEPGRFKDFYQFTFNF AKNPGQKGLDLEMAIAYWNLVLNGRFKFLDLWNKFLLEHH SIPKDTWNLLLDFSTMIADDMSNYDEEGAWPVLIDDFVEF ARPQIAGTKSTTV Description Functional site 1) chain A residue -7 type sequence E description binding site for residue MPD A 1301 source : AC1 2) chain A residue 104 type sequence F description binding site for residue MPD A 1301 source : AC1 3) chain A residue 105 type sequence Q description binding site for residue MPD A 1301 source : AC1 4) chain A residue 106 type sequence M description binding site for residue MPD A 1301 source : AC1 5) chain A residue 107 type sequence G description binding site for residue MPD A 1301 source : AC1 6) chain A residue 1086 type sequence I description binding site for residue O37 A 1302 source : AC2 7) chain A residue 1087 type sequence Q description binding site for residue O37 A 1302 source : AC2 8) chain A residue 1097 type sequence P description binding site for residue O37 A 1302 source : AC2 9) chain A residue 1114 type sequence Q description binding site for residue O37 A 1302 source : AC2 10) chain A residue 1115 type sequence C description binding site for residue O37 A 1302 source : AC2 11) chain A residue 1116 type sequence E description binding site for residue O37 A 1302 source : AC2 12) chain A residue 1117 type sequence F description binding site for residue O37 A 1302 source : AC2 13) chain A residue 1164 type sequence F description binding site for residue O37 A 1302 source : AC2 14) chain A residue 1180 type sequence A description binding site for residue O37 A 1302 source : AC2 15) chain A residue 1181 type sequence Y description binding site for residue O37 A 1302 source : AC2 16) chain A residue 1184 type sequence L description binding site for residue O37 A 1302 source : AC2 17) chain A residue 1115 type SITE sequence C description Essential for interaction with UBE2M => ECO:0000269|PubMed:28581483 source Swiss-Prot : SWS_FT_FI1

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