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eF-site ID
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6os9-R |
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PDB Code
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6os9 |
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Chain
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R |
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click to enlarge
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Title
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human Neurotensin Receptor 1 (hNTSR1) - Gi1 Protein Complex in canonical conformation (C state) |
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Classification
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SIGNALING PROTEIN |
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Compound
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Neurotensin receptor type 1 |
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Source
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(6OS9) |
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Sequence
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R: |
PSSELDVNTDIYSKVLVTAVYLALFVVGTVGNTVTLFTLA
RKKSLQSLQSTVHYHLGSLALSDLLTLLLAMPVELYNFIW
VHHPWAFGDAGCRGYYFLRDACTYATALNVASLSVERYLA
ICHPFKAKTLMSRSRTKKFISAIWLASALLAVPMLFTMGE
QNRSADGQHAGGLVCTPTIHTATVKVVIQVNTFMSFIFPM
VVISVLNTIIANKLTVMVRQAAEQRVQALRHGVRVLRAVV
IAFVVCWLPYHVRRLMFCYISDEQWTPFLYDFYHYFYMVT
NALFYVSSTINPILYNLVSANFRHIF
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Description
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(1) |
Neurotensin receptor type 1, JMV449, Guanine nucleotide-binding protein G(i) subunit alpha-1, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, scFv16
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Functional site
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1)
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chain |
R |
| residue |
260-313 |
| type |
MOD_RES |
| sequence |
ANKLTVMVRQAAEQRVQALRHGVRVLRAVVIAFV
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| description |
Cysteine methyl ester => ECO:0000250|UniProtKB:P63212
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| source |
Swiss-Prot : SWS_FT_FI2
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2)
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chain |
R |
| residue |
206-234 |
| type |
BINDING |
| sequence |
TMGEQNRSADGQHAGGLVCTPTIHTATVK
|
| description |
BINDING => ECO:0007744|PDB:1KJY, ECO:0007744|PDB:1Y3A, ECO:0007744|PDB:2G83, ECO:0007744|PDB:2GTP, ECO:0007744|PDB:2IK8, ECO:0007744|PDB:2OM2, ECO:0007744|PDB:2XNS, ECO:0007744|PDB:3ONW, ECO:0007744|PDB:3QE0, ECO:0007744|PDB:3QI2, ECO:0007744|PDB:3UMR, ECO:0007744|PDB:3UMS, ECO:0007744|PDB:4G5Q
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| source |
Swiss-Prot : SWS_FT_FI4
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3)
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chain |
R |
| residue |
336-353 |
| type |
BINDING |
| sequence |
PFLYDFYHYFYMVTNALF
|
| description |
BINDING => ECO:0007744|PDB:1KJY, ECO:0007744|PDB:1Y3A, ECO:0007744|PDB:2G83, ECO:0007744|PDB:2GTP, ECO:0007744|PDB:2IK8, ECO:0007744|PDB:2OM2, ECO:0007744|PDB:2XNS, ECO:0007744|PDB:3ONW, ECO:0007744|PDB:3QE0, ECO:0007744|PDB:3QI2, ECO:0007744|PDB:3UMR, ECO:0007744|PDB:3UMS, ECO:0007744|PDB:4G5Q
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| source |
Swiss-Prot : SWS_FT_FI4
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4)
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chain |
R |
| residue |
154-170 |
| type |
prosite |
| sequence |
ATALNVASLSVERYLAI
|
| description |
G_PROTEIN_RECEP_F1_1 G-protein coupled receptors family 1 signature. ATAlNVASLSVERYLaI
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| source |
prosite : PS00237
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