eF-site ID 6oqn-A PDB Code 6oqn Chain A click to enlarge Title Crystal structure of Mcl1 with inhibitor 7 Classification APOPTOSIS Compound Induced myeloid leukemia cell differentiation protein Mcl-1 Source (MCL1_HUMAN) Sequence A:  EDELYRQSLEIISRYLREQATGAKDTKPMGRSGATSRKAL ETLRRVGDGVQRNHETAFQGMLRKLDIKNEDDVKSLSRVM IHVFSDGVTNWGRIVTLISFGAFVAKHLKTINQESCIEPL AESITDVLVRTKRDWLVKQRGWDGFVEFFHV Description Functional site 1) chain A residue 227 type sequence A description binding site for residue N0P A 401 source : AC1 2) chain A residue 250 type sequence M description binding site for residue N0P A 401 source : AC1 3) chain A residue 263 type sequence R description binding site for residue N0P A 401 source : AC1 4) chain A residue 267 type sequence L description binding site for residue N0P A 401 source : AC1 5) chain A residue 270 type sequence F description binding site for residue N0P A 401 source : AC1 6) chain A residue 290 type sequence L description binding site for residue N0P A 401 source : AC1 7) chain A residue 253-272 type prosite sequence VFSDGVTNWGRIVTLISFGA description BH1 Apoptosis regulator, Bcl-2 family BH1 motif signature. VFsDGvtNWGRIVTLIsFGA source prosite : PS01080 8) chain A residue 305-316 type prosite sequence WLVKQRGWDGFV description BH2 Apoptosis regulator, Bcl-2 family BH2 motif signature. WLvkqRGWDgFV source prosite : PS01258 9) chain A residue 209-223 type prosite sequence ALETLRRVGDGVQRN description BH3 Apoptosis regulator, Bcl-2 family BH3 motif signature. AletLRrVGDGVQRN source prosite : PS01259 10) chain A residue 194 type CROSSLNK sequence K description Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin) source Swiss-Prot : SWS_FT_FI1 11) chain A residue 197 type CROSSLNK sequence K description Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin) source Swiss-Prot : SWS_FT_FI1

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