eF-site ID 6oov-ABCD PDB Code 6oov Chain A, B, C, D click to enlarge Title Crystal structure of HMCES SRAP domain in complex with palindromic 3' overhang DNA Classification DNA BINDING PROTEIN/DNA Compound Embryonic stem cell-specific 5-hydroxymethylcytosine-binding protein Source (6OOV) Sequence A:  CGRTSCHLPRDVLTRACAYQDRRGQQRLPEWRDPDKYCPS YNKSPQSNSPVLLSRLHFEKDADSSERIIAPMRWGLVPSW FKESDPSKLQFNTTNCRSDTVMEKRSFKVPLGKGRRCVVL ADGFYEWQRCQGTNQRQPYFIYFPQIKVWDNWRLLTMAGI FDCWEPPEGGDVLYSYTIITVDSCKGLSDIHHRMPAILDG EEAVSKWLDFGEVSTQEALKLIHPTENITFHAVSSVVNNS RNNTPECLAPV B:  CGRTSCHLPRDVLTRACAYQDRRGQQRLPEWRDPDKYCPS YNKSPQSNSPVLLSRLHFEKDADSSERIIAPMRWGLVPSW FKESDPSKLQFNTTNCRSDTVMEKRSFKVPLGKGRRCVVL ADGFYEWQRCGTNQRQPYFIYFPQIKVWDNWRLLTMAGIF DCWEPPEGGDVLYSYTIITVDSCKGLSDIHHRMPAILDGE EAVSKWLDFGEVSTQEALKLIHPTENITFHAVSSVVNNSR NNTPECLAPV C:  CAACGTTGTTT D:  CAACGTTGTTTT Description Functional site 1) chain A residue 2 type ACT_SITE sequence C description Nucleophile => ECO:0000269|PubMed:31235913, ECO:0000305|PubMed:30554877 source Swiss-Prot : SWS_FT_FI1 2) chain B residue 2 type ACT_SITE sequence C description Nucleophile => ECO:0000269|PubMed:31235913, ECO:0000305|PubMed:30554877 source Swiss-Prot : SWS_FT_FI1 3) chain A residue 127 type ACT_SITE sequence E description ACT_SITE => ECO:0000269|PubMed:37519246, ECO:0000269|PubMed:37950866 source Swiss-Prot : SWS_FT_FI2 4) chain B residue 127 type ACT_SITE sequence E description ACT_SITE => ECO:0000269|PubMed:37519246, ECO:0000269|PubMed:37950866 source Swiss-Prot : SWS_FT_FI2 5) chain B residue 127 type SITE sequence E description Required for sensing abasic sites => ECO:0000250|UniProtKB:P76318 source Swiss-Prot : SWS_FT_FI3 6) chain A residue 127 type SITE sequence E description Required for sensing abasic sites => ECO:0000250|UniProtKB:P76318 source Swiss-Prot : SWS_FT_FI3 7) chain B residue 210 type SITE sequence H description Required to stabilize abasic sites => ECO:0000250|UniProtKB:P76318 source Swiss-Prot : SWS_FT_FI4 8) chain A residue 210 type SITE sequence H description Required to stabilize abasic sites => ECO:0000250|UniProtKB:P76318 source Swiss-Prot : SWS_FT_FI4 9) chain B residue 2 type MOD_RES sequence C description Thiazolidine linkage to a ring-opened DNA abasic site => ECO:0000269|PubMed:31235913 source Swiss-Prot : SWS_FT_FI5 10) chain A residue 2 type MOD_RES sequence C description Thiazolidine linkage to a ring-opened DNA abasic site => ECO:0000269|PubMed:31235913 source Swiss-Prot : SWS_FT_FI5

Display surface Download Links