|
|
eF-site ID
|
6okk-T |
|
PDB Code
|
6okk |
|
Chain
|
T |
|
click to enlarge
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Title
|
Cryo-EM structure of the Plasmodium falciparum 80S ribosome bound to the anti-protozoan drug emetine, small subunit |
|
Classification
|
ribosome/inhibitor |
|
Compound
|
18S ribosomal RNA |
|
Source
|
ORGANISM_SCIENTIFIC: Plasmodium falciparum (isolate 3D7); |
|
|
Sequence
|
T: |
VHPKKYGQGSRQCRVCSNKHAIIRKYNINICRQCFRERAD
IIGFKKYR
|
|
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Description
|
(1) |
ribosome
|
|
Functional site
|
|
|
1)
|
chain |
T |
| residue |
19 |
| type |
|
| sequence |
C
|
| description |
binding site for residue ZN T 100
|
| source |
: AJ3
|
|
|
2)
|
chain |
T |
| residue |
22 |
| type |
|
| sequence |
C
|
| description |
binding site for residue ZN T 100
|
| source |
: AJ3
|
|
|
3)
|
chain |
T |
| residue |
24 |
| type |
|
| sequence |
N
|
| description |
binding site for residue ZN T 100
|
| source |
: AJ3
|
|
|
4)
|
chain |
T |
| residue |
37 |
| type |
|
| sequence |
C
|
| description |
binding site for residue ZN T 100
|
| source |
: AJ3
|
|
|
5)
|
chain |
T |
| residue |
40 |
| type |
|
| sequence |
C
|
| description |
binding site for residue ZN T 100
|
| source |
: AJ3
|
|
|
6)
|
chain |
T |
| residue |
20-42 |
| type |
prosite |
| sequence |
RVCSNKHAIIRKYNINICRQCFR
|
| description |
RIBOSOMAL_S14 Ribosomal protein S14 signature. RvCsnkhaiirkyn.INICRqCFR
|
| source |
prosite : PS00527
|
|
|
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