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eF-site ID
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6okk-M |
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PDB Code
|
6okk |
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Chain
|
M |
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click to enlarge
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Title
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Cryo-EM structure of the Plasmodium falciparum 80S ribosome bound to the anti-protozoan drug emetine, small subunit |
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Classification
|
ribosome/inhibitor |
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Compound
|
18S ribosomal RNA |
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Source
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ORGANISM_SCIENTIFIC: Plasmodium falciparum (isolate 3D7); |
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Sequence
|
M: |
KRVQTFGKKKTAVAVATVTNGKGLIKLNGKNLDLVEPYIL
KTKVYEPLWLIGSGKLKNLDIRIRVKGGGQTSQIYAIRQA
IGKGIISYYQKYVDESTKKELKDVLLRYDRSLLVGDTRRC
EPKKFGGKGARARYQKSY
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Description
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(1) |
ribosome
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Functional site
|
|
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1)
|
chain |
M |
| residue |
143 |
| type |
|
| sequence |
Y
|
| description |
binding site for residue MG A 2147
|
| source |
: AG8
|
|
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2)
|
chain |
M |
| residue |
49-59 |
| type |
prosite |
| sequence |
VYEPLWLIGSG
|
| description |
TIM_1 Triosephosphate isomerase active site. VYEPLWLIGSG
|
| source |
prosite : PS00171
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|
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3)
|
chain |
M |
| residue |
72-90 |
| type |
prosite |
| sequence |
GGGQTSQIYAIRQAIGKGI
|
| description |
RIBOSOMAL_S9 Ribosomal protein S9 signature. GGGqtSQiyAirqAiGKGI
|
| source |
prosite : PS00360
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