eF-site ID 6ohu-C PDB Code 6ohu Chain C click to enlarge Title Structure of EBP and tamoxifen Classification membrane protein, isomerase/inhibitor Compound 3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase Source (EBP_HUMAN) Sequence C:  PLHPYWPQHLRLDNFVPNDRPTWHILAGLFSVTGVLVVTT WLLSGRTWRRLSLCWFAVCGFIHLVIEGWFVLYYEDLLGD QAFLSQLWKEYAKGDSRYILGDNFTVCMETITACLWGPLS LWVVIAFLRQHPLRFILQLVVSVGQIYGDVLYFLTEHRDG FQHGELGHPLYFWFYFVFMNALWLVLPGVLVLDAVKHLTH AQSTLD Description Functional site 1) chain C residue 35 type sequence L description binding site for residue CTX C 301 source : AC2 2) chain C residue 39 type sequence T description binding site for residue CTX C 301 source : AC2 3) chain C residue 75 type sequence I description binding site for residue CTX C 301 source : AC2 4) chain C residue 79 type sequence I description binding site for residue CTX C 301 source : AC2 5) chain C residue 80 type sequence E description binding site for residue CTX C 301 source : AC2 6) chain C residue 111 type sequence Y description binding site for residue CTX C 301 source : AC2 7) chain C residue 122 type sequence E description binding site for residue CTX C 301 source : AC2 8) chain C residue 188 type sequence Y description binding site for residue CTX C 301 source : AC2 9) chain C residue 192 type sequence M description binding site for residue CTX C 301 source : AC2 10) chain C residue 193 type sequence N description binding site for residue CTX C 301 source : AC2 11) chain C residue 196 type sequence W description binding site for residue CTX C 301 source : AC2 12) chain C residue 29-49 type TRANSMEM sequence WHILAGLFSVTGVLVVTTWLL description Helical => ECO:0000255 source Swiss-Prot : SWS_FT_FI1 13) chain C residue 66-86 type TRANSMEM sequence LCWFAVCGFIHLVIEGWFVLY description Helical => ECO:0000255 source Swiss-Prot : SWS_FT_FI1 14) chain C residue 121-141 type TRANSMEM sequence METITACLWGPLSLWVVIAFL description Helical => ECO:0000255 source Swiss-Prot : SWS_FT_FI1 15) chain C residue 185-205 type TRANSMEM sequence FWFYFVFMNALWLVLPGVLVL description Helical => ECO:0000255 source Swiss-Prot : SWS_FT_FI1

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