eF-site ID 6ohu-AB PDB Code 6ohu Chain A, B click to enlarge Title Structure of EBP and tamoxifen Classification membrane protein, isomerase/inhibitor Compound 3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase Source (EBP_HUMAN) Sequence A:  PLHPYWPQHLRLDNFVPNDRPTWHILAGLFSVTGVLVVTT WLLSGRTWRRLSLCWFAVCGFIHLVIEGWFVLYYEDLLGD QAFLSQLWKEYAKGDSRYILGDNFTVCMETITACLWGPLS LWVVIAFLRQHPLRFILQLVVSVGQIYGDVLYFLTEHRDG FQHGELGHPLYFWFYFVFMNALWLVLPGVLVLDAVKHLTH AQSTLD B:  PLHPYWPQHLRLDNFVPNDRPTWHILAGLFSVTGVLVVTT WLLSGRTWRRLSLCWFAVCGFIHLVIEGWFVLYYEDLLGD QAFLSQLWKEYAKGDSRYILGDNFTVCMETITACLWGPLS LWVVIAFLRQHPLRFILQLVVSVGQIYGDVLYFLTEHRDG FQHGELGHPLYFWFYFVFMNALWLVLPGVLVLDAVKHLTH AQSTLD Description Functional site 1) chain A residue 35 type sequence L description binding site for residue CTX A 301 source : AC1 2) chain A residue 36 type sequence F description binding site for residue CTX A 301 source : AC1 3) chain A residue 39 type sequence T description binding site for residue CTX A 301 source : AC1 4) chain A residue 75 type sequence I description binding site for residue CTX A 301 source : AC1 5) chain A residue 79 type sequence I description binding site for residue CTX A 301 source : AC1 6) chain A residue 80 type sequence E description binding site for residue CTX A 301 source : AC1 7) chain A residue 100 type sequence L description binding site for residue CTX A 301 source : AC1 8) chain A residue 101 type sequence W description binding site for residue CTX A 301 source : AC1 9) chain A residue 188 type sequence Y description binding site for residue CTX A 301 source : AC1 10) chain A residue 192 type sequence M description binding site for residue CTX A 301 source : AC1 11) chain A residue 193 type sequence N description binding site for residue CTX A 301 source : AC1 12) chain A residue 196 type sequence W description binding site for residue CTX A 301 source : AC1 13) chain B residue 35 type sequence L description binding site for Di-peptide CTX B 301 and ILE B 75 source : AC3 14) chain B residue 71 type sequence V description binding site for Di-peptide CTX B 301 and ILE B 75 source : AC3 15) chain B residue 72 type sequence C description binding site for Di-peptide CTX B 301 and ILE B 75 source : AC3 16) chain B residue 73 type sequence G description binding site for Di-peptide CTX B 301 and ILE B 75 source : AC3 17) chain B residue 74 type sequence F description binding site for Di-peptide CTX B 301 and ILE B 75 source : AC3 18) chain B residue 76 type sequence H description binding site for Di-peptide CTX B 301 and ILE B 75 source : AC3 19) chain B residue 77 type sequence L description binding site for Di-peptide CTX B 301 and ILE B 75 source : AC3 20) chain B residue 79 type sequence I description binding site for Di-peptide CTX B 301 and ILE B 75 source : AC3 21) chain B residue 80 type sequence E description binding site for Di-peptide CTX B 301 and ILE B 75 source : AC3 22) chain B residue 111 type sequence Y description binding site for Di-peptide CTX B 301 and ILE B 75 source : AC3 23) chain B residue 188 type sequence Y description binding site for Di-peptide CTX B 301 and ILE B 75 source : AC3 24) chain B residue 192 type sequence M description binding site for Di-peptide CTX B 301 and ILE B 75 source : AC3 25) chain B residue 193 type sequence N description binding site for Di-peptide CTX B 301 and ILE B 75 source : AC3 26) chain B residue 196 type sequence W description binding site for Di-peptide CTX B 301 and ILE B 75 source : AC3 27) chain A residue 29-49 type TRANSMEM sequence WHILAGLFSVTGVLVVTTWLL description Helical => ECO:0000255 source Swiss-Prot : SWS_FT_FI1 28) chain A residue 66-86 type TRANSMEM sequence LCWFAVCGFIHLVIEGWFVLY description Helical => ECO:0000255 source Swiss-Prot : SWS_FT_FI1 29) chain A residue 121-141 type TRANSMEM sequence METITACLWGPLSLWVVIAFL description Helical => ECO:0000255 source Swiss-Prot : SWS_FT_FI1 30) chain A residue 185-205 type TRANSMEM sequence FWFYFVFMNALWLVLPGVLVL description Helical => ECO:0000255 source Swiss-Prot : SWS_FT_FI1 31) chain B residue 29-49 type TRANSMEM sequence WHILAGLFSVTGVLVVTTWLL description Helical => ECO:0000255 source Swiss-Prot : SWS_FT_FI1 32) chain B residue 66-86 type TRANSMEM sequence LCWFAVCGFIHLVIEGWFVLY description Helical => ECO:0000255 source Swiss-Prot : SWS_FT_FI1 33) chain B residue 121-141 type TRANSMEM sequence METITACLWGPLSLWVVIAFL description Helical => ECO:0000255 source Swiss-Prot : SWS_FT_FI1 34) chain B residue 185-205 type TRANSMEM sequence FWFYFVFMNALWLVLPGVLVL description Helical => ECO:0000255 source Swiss-Prot : SWS_FT_FI1

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