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Title
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Herpes simplex virus type 1 (HSV-1) portal vertex-adjacent capsid/CATC, asymmetric unit |
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Classification
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VIRAL PROTEIN |
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Compound
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Major capsid protein |
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Source
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ORGANISM_COMMON: HHV-1; ORGANISM_SCIENTIFIC: Human herpesvirus 1 strain KOS; |
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Sequence
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5: |
PNDDTEQALDKILRGTMRGGAALIGSPRHHLTRQVILTDL
CQPNADRAGTLLLALRHPADLPHLAHQRAPPGRQTERLGE
AWGQLMEATALGSGRAESGCTRAGLVSFNFLVAACAASYD
ARDAADAVRAHVTANYRGTRVGARLDRFSECLRAMVHTHV
FPHEVMRFFGGLVSWVTQDELASVTAVCAGPQEAAHTGHP
GRPRSAVILPACAFVDLDAELGLGGPGAAFLYLVFTYRQR
RDQELCCVYVIKSQLPPRGLEPALERLFGRLRITNTIHGT
EDMTPPAPNRNPDFPLAGLAANPQTPRCSAGQVTNPQFAD
RLYRWQPDLRGRPTARTCTYAAFAELGMMPEDSPRCLHRT
ERFGAVSVPVVILEGVVWRPGEWRACA
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| 6: |
ADGFETDIAIPSGISRPDAAALQRCEGRVVFLPTIRRQLT
LADVAHESFVSGGVSPDTLGLLLAYRRRFPAVITRVLPTR
IVACPLDVGLTHAGTVNLRNTSPVDLCNGDPISLVPPVFE
DVRLDSLDLTLRFPVPLPSPLAREIVARLVARGIRDLPDL
NVLYYNGSRLSLLALGPVNAELRSLVLNMVYSITEGTTII
LTLIPRLFALSAQDGYVNALLQMQSVTREAAQLIHPEGER
RLPLYEALVAWLTHAGQLGDTLALAPVVRVCTFDGAAVVR
SGDMAPVIRYP
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| 7: |
MLADGFETDIAIPSGISRPDAAALQRCEGRVVFLPTIRRQ
LTLADVAHESFVSGGVSPDTLGLLLAYRRRFPAVITRVLP
TRIVACPLDVGLTHAGTVNLRNTSPVDLCNGDPISLVPPV
FEGQATDVRLDSLDLTLRFPVPLPSPLAREIVARLVARGI
RDLNPPDLNVLYYNGSRLSLLADVQQLGPVNAELRSLVLN
MVYSITEGTTIILTLIPRLFALSAQDGYVNALLQMQSVTR
EAAQLIHPEAPALMQDGERRLPLYEALVAWLTHAGQLGDT
LALAPVVRVCTFDGAAVVRSGDMAPVIRYP
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| A: |
MLADGFETDIAIPSGISRPDAAALQRCEGRVVFLPTIRRQ
LTLADVAHESFVSGGVSPDTLGLLLAYRRRFPAVITRVLP
TRIVACPLDVGLTHAGTVNLRNTSPVDLCNGDPISLVPPV
FEGQATDVRLDSLDLTLRFPVPLPSPLAREIVARLVARGI
RDLNPPDLNVLYYNGSRLSLLADVQQLGPVNAELRSLVLN
MVYSITEGTTIILTLIPRLFALSAQDGYVNALLQMQSVTR
EAAQLIHPEAPALMQDGERRLPLYEALVAWLTHAGQLGDT
LALAPVVRVCTFDGAAVVRSGDMAPVIRYP
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| B: |
QRTGRSALAVLIRACYRLQQQLQRTRRALLHHSDAVLTSL
HHVRMLLG
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| C: |
MNAHLANEVQYDLGHVPGRPSSLVHVIISSECLAAAGIPL
AALMRANFQVEIQTRAHATGDCTPWCTAFAAYVPADAVGE
LLAPVVPAHPGLLPRASSAGGLFVSLPVVCDAQGVYDPYA
VAALRLAWGSGASCARVILFSYDELVPPNTRYAADSTRIM
RVCRHLCRYVALLGAAAPPAAKEAAAHLSMGLGPPISPEE
QLTAPGGDTTAAQDVSIAQENEEILALVQRSLVEWLDRGW
EALAGGDRPDWLWSRRSISVVLRHHYGTKQRFVVVSYENS
VAWGGRRARPPLLSSALATALTEACAAERVVRPHQLSPAG
QAELLLRFPALEVPLRHPRPVLPPFDIAAEVAFTARIHLA
CLRALGQAIRAALQGGPRISQRLRYDFGPDQRAWLGEVTR
RFPILLENLMRAVEGTAPDAFFHTAYALAVLAHLGGRVVP
LGDDLPARFADSDGHYVFDYYSTSGDTLRLNNRPIAVAMD
GDVSKREQSKCRFMEAVPSTAPRRVCEQYLPGESYAYLCL
GFNRRLCGIVVFPGGFAFTINIAAYLSLSDPVARAAVLRF
CRKVS
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| D: |
GSPRHHLTRQVILTDLCQPNADRAGTLLLALRHPADLPHL
AHQRAPPGRQTERLGEAWGQLMEATALGSGRAESGCTRAG
LVSFNFLVAACAASYDARDAADAVRAHVTANYRGTRVGAR
LDRFSECLRAMVHTHVFPHEVMRFFGGLVSWVTQDELASV
TAVCAGPQEAAHTGHPGRPRSAVILPACAFVDLDAELGLG
GPGAAFLYLVFTYRQRRDQELCCVYVIKSQLPPRGLEPAL
ERLFGRLRITNTIHGTEDMTPPAPNRNPDFPLAGLAANPQ
TPRCSAGQVTNPQFADRLYRWQPDLRGRPTARTCTYAAFA
ELGMMPEDSPRCLHRTERFGAVSVPVVILEGVVWRPGEWR
ACA
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| E: |
VPQFHRPSTVTTDSVRALGMRGLVLATNNSQFIMDNNHPH
PQGTQGAVREFLRGQAAALTDLGLAHANNTFTPQPMFAGD
APAAWLRPAFGLRRTYSPFVV
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| F: |
VPQFHRPSTVTTDSVRALGMRGLVLATNNSQFIMDNNHPH
PQGTQGAVREFLRGQAAALTDLGLAHANNTFTPQPMFAGD
APAAWLRPAFGLRRTYSPFVV
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| G: |
MDPYCPFDALDVWEHRRFIVADSRNFITPEFPRDFWMSPV
FNLPRETAAEQVVVLQAQRTAAAAALENAAMQAAELPVDI
ERRLRPIERNVH
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| H: |
ADGFETDIAIPSGISRPDAAALQRCEGRVVFLPTIRRQLT
LADVAHESFVSGGVSPDTLGLLLAYRRRFPAVITRVLPTR
IVACPLDVGLTHAGTVNLRNTSPVDLCNGDPISLVPPVFE
DVRLDSLDLTLRFPVPLPSPLAREIVARLVARGIRDLPDL
NVLYYNGSRLSLLALGPVNAELRSLVLNMVYSITEGTTII
LTLIPRLFALSAQDGYVNALLQMQSVTREAAQLIHPEGER
RLPLYEALVAWLTHAGQLGDTLALAPVVRVCTFDGAAVVR
SGDMAPVIRYP
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| K: |
WEHRRFIVADSRNFITPEFPRDFWMSPVFNLPRETAAEQV
VVLQAQRTAAAAALENAAMQAAELPVDIERRLRPIERNV
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| L: |
VPQFHRPSTVTTDSVRALGMRGLVLATNNSQFIMDNNHPH
PQGTQGAVREFLRGQAAALTDLGLAHANNTFTPQPMFAGD
APAAWLRPAFGLRRTYSPFVV
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| O: |
QRTGRSALAVLIRACYRLQQQLQRTRRALLHHSDAVLTSL
HHVRMLLG
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| P: |
VPQFHRPSTVTTDSVRALGMRGLVLATNNSQFIMDNNHPH
PQGTQGAVREFLRGQAAALTDLGLAHANNTFTPQPMFAGD
APAAWLRPAFGLRRTYSPFVV
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| S: |
GYRYAAAMVPTGSLLSTIEVASHRRLFDFFSRVRSDANSL
YDVEFDALLGSYCNTLSLVRFLELGLSVACVCTKFPELAY
MNEGRVQFEVHQPLIARDGPHPIEQPTHNYMTKIIDRRAL
NAAFSLATEAIALLTGEALDGTGISAHRQLRAIQQLARNV
QAVLGAFERGTADQMLHVLLEKAPPLALLLPMQRYLDNGR
LATRVARATLVAELKRSFCETSFFLGKAGHRREAVEAWLV
DLTTATQPSVAVPRLTHADTRGRPVDGVLVTTAPIKQRLL
QSFLKVEDTEADVPVTYGEMVLNTLDELESAPQTTRVRAD
LVSIGEKLIFLEALEKRIYAATNVPYPLVGAMDLTFVLPL
GLFNPVMERFAAHAGDLVPAPGHPDPRAFPPRQLFFWGKD
RQVLRLSLEHAIGTVCHPSLMNVDAAVGGLNRDPVEAANP
YGAYVAAPAGPAADMQQLFLNAWGQRLAHGRVRWVAEGQM
TPEQFMQPDNANLALELHPAFDFFVGVADVELPGGDVPPA
GPGEIQATWRVVNGNLPLALCPAAFRDARGLELGVGRHAM
APATIAAVRGAFEDRNYPAVFYLLQAAIHGSEHVFCALAR
LVVQCITSYWNNTRCAAFVNDYSLVSYVVTYLGGDLPEEC
MAVYRDLVAHVEALAQLVDDFTLTGPELGGQAQAELNHLM
RDPALLPPLVWDCDALMRRAALDRHRDCRVSAGGHDPVYA
AACNVATADFNRNDGQLLHNTQARAADAADDRPHRGADWT
VHHKIYYYVMVPAFSRGRCCTAGVRFDRVYATLQNMVVPE
ITPGEDCPSDPVTDPAHPLHPANLVANTVNAMFHNGRVVV
DGPAMLTLQVLAHNMAERTTALLCSAAPDAGANTASTTNM
RIFDGALHAGILLMAPQHLDHTIQNGDYFYPLPVHALFAG
ADHVANAPNFPPALRDLSRQVPLVPPALGANYFSSIRQPV
VQHVRESAAGENALTYALMAGYFKISPVALHHQLKTGLHP
GFGFTVVRQDRFVTENVLFSERASEAYFLGQLQVARHETG
GGVNFTLTQPRGNVDLGVGYTAVVATATVRNPVTDMGNLP
QNFYLGRGAPPLLDNAAAVYLRNAVVAGNRLGPAQPVPVF
GCAQVPRRAGMDHGQDAVCEFIATPVSTDVNYFRRPCNPR
GRAAGGVYAGDKEGDVTALMYDHGQSDPSRAFAATANPWA
SQRFSYGDLLYNGAYHLNGASPVLSPCFKFFTSADIAAKH
RCLERLIVETGSAVSTATAASDVQFKRPPGCRELVEDPCG
LFQEAYPLTCASDPALLRSARNGEAHARETHFAQYLVYDA
SPLKGLAL
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| T: |
RDPPGYRYAAAMVPTGSLLSTIEVASHRRLFDFFSRVRSD
ANSLYDVEFDALLGSYCNTLSLVRFLELGLSVACVCTKFP
ELAYMNEGRVQFEVHQPLIARDGPHPIEQPTHNYMTKIID
RRALNAAFSLATEAIALLTGEALDGTGISAHRQLRAIQQL
ARNVQAVLGAFERGTADQMLHVLLEKAPPLALLLPMQRYL
DNGRLATRVARATLVAELKRSFCETSFFLGKAGHRREAVE
AWLVDLTTATQPSVAVPRLTHADTRGRPVDGVLVTTAPIK
QRLLQSFLKVEDTEADVPVTYGEMVLNGANLVTALVMGKA
VRSLDDVGRHLLEMQEEQLDLNRQTLDELESAPQTTRVRA
DLVSIGEKLIFLEALEKRIYAATNVPYPLVGAMDLTFVLP
LGLFNPVMERFAAHAGDLVPAPGHPDPRAFPPRQLFFWGK
DRQVLRLSLEHAIGTVCHPSLMNVDAAVGGLNRDPVEAAN
PYGAYVAAPAGPAADMQQLFLNAWGQRLAHGRVRWVAEGQ
MTPEQFMQPDNANLALELHPAFDFFVGVADVELPGGDVPP
AGPGEIQATWRVVNGNLPLALCPAAFRDARGLELGVGRHA
MAPATIAAVRGAFEDRNYPAVFYLLQAAIHGSEHVFCALA
RLVVQCITSYWNNTRCAAFVNDYSLVSYVVTYLGGDLPEE
CMAVYRDLVAHVEALAQLVDDFTLTGPELGGQAQAELNHL
MRDPALLPPLVWDCDALMRRAALDRHRDCRVSAGGHDPVY
AAACNVATADFNRNDGQLLHNTQARAADAADDRPHRGADW
TVHHKIYYYVMVPAFSRGRCCTAGVRFDRVYATLQNMVVP
EITPGEDCPSDPVTDPAHPLHPANLVANTVNAMFHNGRVV
VDGPAMLTLQVLAHNMAERTTALLCSAAPDAGANTASTTN
MRIFDGALHAGILLMAPQHLDHTIQNGDYFYPLPVHALFA
GADHVANAPNFPPALRDLSRQVPLVPPALGANYFSSIRQP
VVQHVRESAAGENALTYALMAGYFKISPVALHHQLKTGLH
PGFGFTVVRQDRFVTENVLFSERASEAYFLGQLQVARHET
GGGVNFTLTQPRGNVDLGVGYTAVVATATVRNPVTDMGNL
PQNFYLGRGAPPLLDNAAAVYLRNAVVAGNRLGPAQPVPV
FGCAQVPRRAGMDHGQDAVCEFIATPVSTDVNYFRRPCNP
RGRAAGGVYAGDKEGDVTALMYDHGQSDPSRAFAATANPW
ASQRFSYGDLLYNGAYHLNGASPVLSPCFKFFTSADIAAK
HRCLERLIVETGSAVSTATAASDVQFKRPPGCRELVEDPC
GLFQEAYPLTCASDPALLRSARNGEAHARETHFAQYLVYD
ASPLKGLAL
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| W: |
PPGYRYAAAMVPTGSLLSTIEVASHRRLFDFFSRVRSDAN
SLYDVEFDALLGSYCNTLSLVRFLELGLSVACVCTKFPEL
AYMNEGRVQFEVHQPLIARDGPHPIEQPTHNYMTKIIDRR
ALNAAFSLATEAIALLTGEALDGTGISAHRQLRAIQQLAR
NVQAVLGAFERGTADQMLHVLLEKAPPLALLLPMQRYLDN
GRLATRVARATLVAELKRSFCETSFFLGKAGHRREAVEAW
LVDLTTATQPSVAVPRLTHADTRGRPVDGVLVTTAPIKQR
LLQSFLKVEDTEADVPVTYGEMVLNGANLVTALVMGKAVR
SLDDVGRHLLEMQEEQLDLNRQTLDELESAPQTTRVRADL
VSIGEKLIFLEALEKRIYAATNVPYPLVGAMDLTFVLPLG
LFNPVMERFAAHAGDLVPAPGHPDPRAFPPRQLFFWGKDR
QVLRLSLEHAIGTVCHPSLMNVDAAVGGLNRDPVEAANPY
GAYVAAPAGPAADMQQLFLNAWGQRLAHGRVRWVAEGQMT
PEQFMQPDNANLALELHPAFDFFVGVADVELPGGDVPPAG
PGEIQATWRVVNGNLPLALCPAAFRDARGLELGVGRHAMA
PATIAAVRGAFEDRNYPAVFYLLQAAIHGSEHVFCALARL
VVQCITSYWNNTRCAAFVNDYSLVSYVVTYLGGDLPEECM
AVYRDLVAHVEALAQLVDDFTLTGPELGGQAQAELNHLMR
DPALLPPLVWDCDALMRRAALDRHRDCRVSAGGHDPVYAA
ACNVATADFNRNDGQLLHNTQARAADAADDRPHRGADWTV
HHKIYYYVMVPAFSRGRCCTAGVRFDRVYATLQNMVVPEI
TPGEDCPSDPVTDPAHPLHPANLVANTVNAMFHNGRVVVD
GPAMLTLQVLAHNMAERTTALLCSAAPDAGANTASTTNMR
IFDGALHAGILLMAPQHLDHTIQNGDYFYPLPVHALFAGA
DHVANAPNFPPALRDLSRQVPLVPPALGANYFSSIRQPVV
QHVRESAAGENALTYALMAGYFKISPVALHHQLKTGLHPG
FGFTVVRQDRFVTENVLFSERASEAYFLGQLQVARHETGG
GVNFTLTQPRGNVDLGVGYTAVVATATVRNPVTDMGNLPQ
NFYLGRGAPPLLDNAAAVYLRNAVVAGNRLGPAQPVPVFG
CAQVPRRAGMDHGQDAVCEFIATPVSTDVNYFRRPCNPRG
RAAGGVYAGDKEGDVTALMYDHGQSDPSRAFAATANPWAS
QRFSYGDLLYNGAYHLNGASPVLSPCFKFFTSADIAAKHR
CLERLIVETGSAVSTATAASDVQFKRPPGCRELVEDPCGL
FQEAYPLTCASDPALLRSARNGEAHARETHFAQYLVYDAS
PLKGLAL
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| X: |
YDVEFDALLGSYCNTLSLVRFLELGLSVACVCTKFPELAY
MNEGRVQFEVHQPLIARDGPHPIEQPTHNYMTKIIDRRAL
NAAFSLATEAIALLTHRQLRAIQQLARNVQAVLGAFERGT
ADQMLHVLLEKAPPLALLLPMQRYLDNTRVARATLVAELK
RSFCETSFFLGKAGHRREAVEAWLVDLTTATQPSVAVPRL
THADTRGRPVDGVLVTTAPIKQRLLQSFLKVEDTEADVPV
TYGEMVLNGANLVTALVMGKAVRSLDDVGRHLLEMQEEQL
DLNRQTLDELESAPQTTRVRADLVSIGEKLIFLEALEKRI
YAATNVPYPLVGAMDLTFVLPLGLFNPVMERFAAHAGDLV
PAPGHPDPRAFPPRQLFFWGKDRQVLRLSLEHAIGTVCHP
SLMNVDAAVGGLNRDPVEAANPYGAYVAAPAGPAADMQQL
FLNAWGQRLAHGRVRWVAEGQMTPEQFMQPDNANLALELH
PAFDFFVGVADVELPGGDVPPAGPGEIQATWRVVNGNLPL
ALCPAAFRDARGLELGVGRHAMAPATIAAVRGAFEDRNYP
AVFYLLQAAIHGSEHVFCALARLVVQCITSYWNNTRCAAF
VNDYSLVSYVVTYLGGDLPEECMAVYRDLVAHVEALAQLV
DDFTLTGPELGGQAQAELNHLMRDPALLPPLVWDCDALMR
RAALDRHRDCRVSAGGHDPVYAAACNVATADFNRNDGQLL
HNTQARAADAADDRPHRGADWTVHHKIYYYVMVPAFSRGR
CCTAGVRFDRVYATLQNMVVPEITPGEDCPSDPVTDPAHP
LHPANLVANTVNAMFHNGRVVVDGPAMLTLQVLAHNMAER
TTALLCSAAPDAGANTASTTNMRIFDGALHAGILLMAPQH
LDHTIQNGDYFYPLPVHALFAGADHVANAPNFPPALRDLS
RQVPLVPPALGANYFSSIRQPVVQHVRESAAGENALTYAL
MAGYFKISPVALHHQLKTGLHPGFGFTVVRQDRFVTENVL
FSERASEAYFLGQLQVARHETGGGVNFTLTQPRGNVDLGV
GYTAVVATATVRNPVTDMGNLPQNFYLGRGAPPLLDNAAA
VYLRNAVVAGNRLGPAQPVPVFGCAQVPRRAGMDHGQDAV
CEFIATPVSTDVNYFRRPCNPRGRAAGGVYAGDKEGDVTA
LMYDHGQSDPSRAFAATANPWASQRFSYGDLLYNGAYHLN
GASPVLSPCFKFFTSADIAAKHRCLERLIVETGSAVSTAT
AASDVQFKRPPGCRELVEDPCGLFQEAYPLTCASDPALLR
SARNGEAHARETHFAQYLVYDASPLKGLAL
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Description
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(1) |
Major capsid protein, Small capsomere-interacting protein, Triplex capsid protein 1, Triplex capsid protein 2, Capsid vertex component 1, Capsid vertex component 2, Large tegument protein deneddylase (E.C.3.4.19.12,3.4.22.-)
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