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eF-site ID
|
6o9z-L |
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PDB Code
|
6o9z |
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Chain
|
L |
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click to enlarge
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Title
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Electron cryo-microscopy of the eukaryotic translation initiation factor 2B bound to eukaryotic translation initiation factor 2 from Homo sapiens |
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Classification
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TRANSLATION |
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Compound
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Translation initiation factor eIF-2B subunit epsilon |
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Source
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(IF2A_HUMAN) |
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Sequence
|
L: |
CRFYQHKFPEVEDVVMVNVRSIAEMGAYVSLLEYNNIEGM
ILLSELXRRRIRSINKLIRIGRNECVVVIRVDKEKGYIDL
SKRRVSPEEAIKCEDKFTKSKTVYSILRHVAEVLEYTKDE
QLESLFQRTAWVFDDKYKRPGYGAYDAFKHAVSDPSILDS
LDLNEDEREVLINNIN
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Description
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(1) |
Translation initiation factor eIF-2B subunit epsilon, Translation initiation factor eIF-2B subunit beta, Translation initiation factor eIF-2B subunit delta, Translation initiation factor eIF-2B subunit alpha, Translation initiation factor eIF-2B subunit gamma, Eukaryotic translation initiation factor 2 subunit 1
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Functional site
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|
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1)
|
chain |
L |
| residue |
48 |
| type |
MOD_RES |
| sequence |
S
|
| description |
Phosphoserine; by HRI => ECO:0000250|UniProtKB:P83268
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| source |
Swiss-Prot : SWS_FT_FI1
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|
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2)
|
chain |
L |
| residue |
51 |
| type |
MOD_RES |
| sequence |
X
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| description |
Phosphoserine => ECO:0007744|PubMed:19690332, ECO:0007744|PubMed:24275569
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| source |
Swiss-Prot : SWS_FT_FI2
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|
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3)
|
chain |
L |
| residue |
140 |
| type |
MOD_RES |
| sequence |
K
|
| description |
N6-acetyllysine => ECO:0007744|PubMed:19608861
|
| source |
Swiss-Prot : SWS_FT_FI3
|
|
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4)
|
chain |
L |
| residue |
157 |
| type |
MOD_RES |
| sequence |
S
|
| description |
Phosphoserine => ECO:0007744|PubMed:23186163
|
| source |
Swiss-Prot : SWS_FT_FI4
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