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eF-site ID
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6o9z-A |
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PDB Code
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6o9z |
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Chain
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A |
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Title
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Electron cryo-microscopy of the eukaryotic translation initiation factor 2B bound to eukaryotic translation initiation factor 2 from Homo sapiens |
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Classification
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TRANSLATION |
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Compound
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Translation initiation factor eIF-2B subunit epsilon |
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Source
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(IF2A_HUMAN) |
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Sequence
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A: |
PPLQAVLVADSFDRRFFPISKDQPRVLLPLANVALIDYTL
EFLTATGVQETFVFCCWKAAQIKEHLLKSKWCRPTSLNVV
RIITSELYRSLGDVLRDVDAKALVRSDFLLVYGDVISNIN
ITRALEEHRLRRKLEKNVSVMTMIFKESSPSHPTRCHEDN
VVVAVDSTTNRVLHFQKTQGLRRFAFPLSLFQGSSDGVEV
RYDLLDCHISICSPQVAQLFTDNFDYQTRDDFVRGLLVNE
EILGNQIHMHVTAKEYGARVSNLHMYSAVCADVIRRWVYP
LTPEANFTDSTTQSCTHSRHNIYRGPEVSLGHGSILEENV
LLGSGTVIGSNCFITNSVIGPGCHIGDNVVLDQTYLWQGV
RVAAGAQIHQSLLCDNAEVKERVTLKPRSVLTSQVVVGPN
ITLPEGSVISLHPPDAEEDEDDGEFS
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Description
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(1) |
Translation initiation factor eIF-2B subunit epsilon, Translation initiation factor eIF-2B subunit beta, Translation initiation factor eIF-2B subunit delta, Translation initiation factor eIF-2B subunit alpha, Translation initiation factor eIF-2B subunit gamma, Eukaryotic translation initiation factor 2 subunit 1
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Functional site
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1)
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chain |
A |
| residue |
61 |
| type |
CROSSLNK |
| sequence |
K
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| description |
Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin) => ECO:0000250|UniProtKB:Q64350
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| source |
Swiss-Prot : SWS_FT_FI8
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2)
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chain |
A |
| residue |
103 |
| type |
CROSSLNK |
| sequence |
K
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| description |
Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin) => ECO:0000250|UniProtKB:Q64350
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| source |
Swiss-Prot : SWS_FT_FI8
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3)
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chain |
A |
| residue |
141 |
| type |
CROSSLNK |
| sequence |
K
|
| description |
Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin) => ECO:0000250|UniProtKB:Q64350
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| source |
Swiss-Prot : SWS_FT_FI8
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4)
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chain |
A |
| residue |
217 |
| type |
CROSSLNK |
| sequence |
K
|
| description |
Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin) => ECO:0000250|UniProtKB:Q64350
|
| source |
Swiss-Prot : SWS_FT_FI8
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