eF-site ID 6o8c-A PDB Code 6o8c Chain A click to enlarge Title Crystal structure of STING CTT in complex with TBK1 Classification IMMUNE SYSTEM Compound Serine/threonine-protein kinase TBK1 Source (STING_HUMAN) Sequence A:  GLDGICQSTSNHLWLLSDILGQGATANVFRGRHKKTGDLY AVKVFNNISFLRPVDVQMREFEVLKKLNHKNIVKLFAIEE ETTTRHKVLIMEFCPCGSLYTVLEEPSNAYGLPESEFLIV LRDVVGGMNHLRENGIVHRDIKPGNIMRVIGEDGQSVYKL TDFGAATEEYLHPDMYERAVLRKDHQKKYGATVDLWSVGV TFYHAATGSLPFRPFEGPRRNKEVMYKIITGKPSGAISGV QKAENGPIDWSGDMPLSCSLSQGLQALLTPVLANILEADQ EKCWGFDQFFAETSDVLHRMVIHVFSLQHMTAHKIYIHSY NTAAVFHELVYKQTKIVSSNQELIYEGRRLVLELGRLAQH FPKTTEENPIFVTSREQLNTVGLRYEKISLPKIHPRYDLD GDASMAKAVTGVVCYACRTASTLLLYQELMRKGVRWLVEL VKDDYNETVHKKTEVVITLDFCIRNIEKTVKVVNLEAAEL GEISDIHTKLLRLSSSQGTIESSLQDISSRLSPGGLLADT WAHQEGTHPRDRNVEKLQVLLNCITEIYYQFKKDKAERRL AYNEEQIHKFDKQKLYYHATKAMSHFSEECVRKYEAFKDK SEEWMRKMLHLRKQLLSLTNQCFDIEEEVSKYQDYT Description Functional site 1) chain A residue 15 type sequence L description binding site for residue BX7 A 701 source : AC1 2) chain A residue 16 type sequence G description binding site for residue BX7 A 701 source : AC1 3) chain A residue 17 type sequence Q description binding site for residue BX7 A 701 source : AC1 4) chain A residue 18 type sequence G description binding site for residue BX7 A 701 source : AC1 5) chain A residue 21 type sequence A description binding site for residue BX7 A 701 source : AC1 6) chain A residue 23 type sequence V description binding site for residue BX7 A 701 source : AC1 7) chain A residue 36 type sequence A description binding site for residue BX7 A 701 source : AC1 8) chain A residue 38 type sequence K description binding site for residue BX7 A 701 source : AC1 9) chain A residue 86 type sequence M description binding site for residue BX7 A 701 source : AC1 10) chain A residue 87 type sequence E description binding site for residue BX7 A 701 source : AC1 11) chain A residue 88 type sequence F description binding site for residue BX7 A 701 source : AC1 12) chain A residue 89 type sequence C description binding site for residue BX7 A 701 source : AC1 13) chain A residue 92 type sequence G description binding site for residue BX7 A 701 source : AC1 14) chain A residue 93 type sequence S description binding site for residue BX7 A 701 source : AC1 15) chain A residue 96 type sequence T description binding site for residue BX7 A 701 source : AC1 16) chain A residue 139 type sequence G description binding site for residue BX7 A 701 source : AC1 17) chain A residue 142 type sequence M description binding site for residue BX7 A 701 source : AC1 18) chain A residue 156 type sequence T description binding site for residue BX7 A 701 source : AC1 19) chain A residue 401 type MOD_RES sequence K description Phosphoserine; by TBK1 => ECO:0000269|PubMed:25636800, ECO:0000269|PubMed:27302953, ECO:0000269|PubMed:32753499 source Swiss-Prot : SWS_FT_FI4 20) chain A residue 15-38 type prosite sequence LGQGATANVFRGRHKKTGDLYAVK description PROTEIN_KINASE_ATP Protein kinases ATP-binding region signature. LGQGATANVFrGrhkktgdl..........YAVK source prosite : PS00107

Display surface Download Links