eF-site ID 6o5x-ABCD PDB Code 6o5x Chain A, B, C, D click to enlarge Title Crystal Structure of multi-drug resistant HIV-1 protease PR-S17 with substrate analog CA-p2 Classification HYDROLASE, Viral Protein Compound HIV-1 protease PR-S17 Source (I7BFC3_9HIV1) Sequence A:  PQITLWQRPIVTIKIGGQLREALLDTGADDTVLEDIDLPG RWKPKLIVGIGGFVKVRQYEQVPIEIAGHKVVGTVLIGPT PSNIIGRNLMTQLGATLNF B:  PQITLWQRPIVTIKIGGQLREALLDTGADDTVLEDIDLPG RWKPKLIVGIGGFVKVRQYEQVPIEIAGHKVVGTVLIGPT PSNIIGRNLMTQLGATLNF C:  PQITLWQRPIVTIKIGGQLREALLDTGADDTVLEDIDLPG RWKPKLIVGIGGFVKVRQYEQVPIEIAGHKVVGTVLIGPT PSNIIGRNLMTQLGATLNF D:  PQITLWQRPIVTIKIGGQLREALLDTGADDTVLEDIDLPG RWKPKLIVGIGGFVKVRQYEQVPIEIAGHKVVGTVLIGPT PSNIIGRNLMTQLGATLNF Description Functional site 1) chain A residue 8 type sequence R description binding site for residue CL A 101 source : AC1 2) chain A residue 40 type sequence G description binding site for residue CL A 102 source : AC2 3) chain A residue 41 type sequence R description binding site for residue CL A 102 source : AC2 4) chain A residue 48 type sequence V description binding site for residue CL A 103 source : AC3 5) chain A residue 12 type sequence T description binding site for residue CL A 104 source : AC4 6) chain A residue 67 type sequence A description binding site for residue CL A 104 source : AC4 7) chain A residue 8 type sequence R description binding site for residue 0Q4 B 101 source : AC5 8) chain A residue 23 type sequence L description binding site for residue 0Q4 B 101 source : AC5 9) chain A residue 25 type sequence D description binding site for residue 0Q4 B 101 source : AC5 10) chain A residue 27 type sequence G description binding site for residue 0Q4 B 101 source : AC5 11) chain A residue 28 type sequence A description binding site for residue 0Q4 B 101 source : AC5 12) chain A residue 29 type sequence D description binding site for residue 0Q4 B 101 source : AC5 13) chain A residue 30 type sequence D description binding site for residue 0Q4 B 101 source : AC5 14) chain A residue 48 type sequence V description binding site for residue 0Q4 B 101 source : AC5 15) chain A residue 49 type sequence G description binding site for residue 0Q4 B 101 source : AC5 16) chain B residue 8 type sequence R description binding site for residue 0Q4 B 101 source : AC5 17) chain B residue 25 type sequence D description binding site for residue 0Q4 B 101 source : AC5 18) chain B residue 27 type sequence G description binding site for residue 0Q4 B 101 source : AC5 19) chain B residue 28 type sequence A description binding site for residue 0Q4 B 101 source : AC5 20) chain B residue 29 type sequence D description binding site for residue 0Q4 B 101 source : AC5 21) chain B residue 30 type sequence D description binding site for residue 0Q4 B 101 source : AC5 22) chain B residue 46 type sequence L description binding site for residue 0Q4 B 101 source : AC5 23) chain B residue 47 type sequence I description binding site for residue 0Q4 B 101 source : AC5 24) chain B residue 48 type sequence V description binding site for residue 0Q4 B 101 source : AC5 25) chain B residue 49 type sequence G description binding site for residue 0Q4 B 101 source : AC5 26) chain B residue 50 type sequence I description binding site for residue 0Q4 B 101 source : AC5 27) chain B residue 82 type sequence S description binding site for residue 0Q4 B 101 source : AC5 28) chain D residue 45 type sequence K description binding site for residue 0Q4 B 101 source : AC5 29) chain D residue 46 type sequence L description binding site for residue 0Q4 B 101 source : AC5 30) chain B residue 73 type sequence G description binding site for residue CL B 102 source : AC6 31) chain B residue 74 type sequence T description binding site for residue CL B 102 source : AC6 32) chain B residue 88 type sequence N description binding site for residue CL B 102 source : AC6 33) chain B residue 54 type sequence V description binding site for residue CL B 103 source : AC7 34) chain B residue 55 type sequence K description binding site for residue CL B 103 source : AC7 35) chain B residue 61 type sequence Q description binding site for residue NA B 104 source : AC8 36) chain C residue 4 type sequence T description binding site for residue CL C 101 source : AC9 37) chain C residue 6 type sequence W description binding site for residue CL C 101 source : AC9 38) chain C residue 7 type sequence Q description binding site for residue CL C 101 source : AC9 39) chain B residue 46 type sequence L description binding site for residue CL C 102 source : AD1 40) chain C residue 8 type sequence R description binding site for residue CL C 102 source : AD1 41) chain C residue 47 type sequence I description binding site for residue CL C 103 source : AD2 42) chain C residue 48 type sequence V description binding site for residue CL C 103 source : AD2 43) chain C residue 8 type sequence R description binding site for residue CL C 104 source : AD3 44) chain C residue 12 type sequence T description binding site for residue CL C 105 source : AD4 45) chain B residue 45 type sequence K description binding site for residue 0Q4 D 101 source : AD5 46) chain B residue 46 type sequence L description binding site for residue 0Q4 D 101 source : AD5 47) chain C residue 8 type sequence R description binding site for residue 0Q4 D 101 source : AD5 48) chain C residue 23 type sequence L description binding site for residue 0Q4 D 101 source : AD5 49) chain C residue 25 type sequence D description binding site for residue 0Q4 D 101 source : AD5 50) chain C residue 27 type sequence G description binding site for residue 0Q4 D 101 source : AD5 51) chain C residue 28 type sequence A description binding site for residue 0Q4 D 101 source : AD5 52) chain C residue 29 type sequence D description binding site for residue 0Q4 D 101 source : AD5 53) chain C residue 48 type sequence V description binding site for residue 0Q4 D 101 source : AD5 54) chain C residue 49 type sequence G description binding site for residue 0Q4 D 101 source : AD5 55) chain D residue 8 type sequence R description binding site for residue 0Q4 D 101 source : AD5 56) chain D residue 23 type sequence L description binding site for residue 0Q4 D 101 source : AD5 57) chain D residue 25 type sequence D description binding site for residue 0Q4 D 101 source : AD5 58) chain D residue 27 type sequence G description binding site for residue 0Q4 D 101 source : AD5 59) chain D residue 28 type sequence A description binding site for residue 0Q4 D 101 source : AD5 60) chain D residue 29 type sequence D description binding site for residue 0Q4 D 101 source : AD5 61) chain D residue 30 type sequence D description binding site for residue 0Q4 D 101 source : AD5 62) chain D residue 46 type sequence L description binding site for residue 0Q4 D 101 source : AD5 63) chain D residue 47 type sequence I description binding site for residue 0Q4 D 101 source : AD5 64) chain D residue 48 type sequence V description binding site for residue 0Q4 D 101 source : AD5 65) chain D residue 49 type sequence G description binding site for residue 0Q4 D 101 source : AD5 66) chain D residue 50 type sequence I description binding site for residue 0Q4 D 101 source : AD5 67) chain D residue 81 type sequence P description binding site for residue 0Q4 D 101 source : AD5 68) chain D residue 82 type sequence S description binding site for residue 0Q4 D 101 source : AD5 69) chain D residue 74 type sequence T description binding site for residue CL D 102 source : AD6 70) chain D residue 88 type sequence N description binding site for residue CL D 102 source : AD6 71) chain A residue 22-33 type prosite sequence ALLDTGADDTVL description ASP_PROTEASE Eukaryotic and viral aspartyl proteases active site. ALLDTGADDTVL source prosite : PS00141

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