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eF-site ID
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6o5b-G |
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PDB Code
|
6o5b |
|
Chain
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G |
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click to enlarge
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Title
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Monomer of a cation channel |
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Classification
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TRANSPORT PROTEIN |
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Compound
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Calcium uniporter protein, mitochondrial |
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Source
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(EMRE_HUMAN) |
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Sequence
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G: |
VTVVYQNGLPVISVRLPSRRERCQFTLKPISDSVGVFLRQ
LQEEDRGIDRVAIYSPDGVRVAASTGIDLLLLDDFKLVIN
DLTYHVRPPKNDVKTLVQQLYTTLCIEQHQLNKERELIER
LEDLKEQLAPLEKVRIEISRKAEKRTTLVLWGGLAYMATQ
FGILARLTWWEYSWDIMEPVTYFITYGSAMAMYAYFVMTR
QEYVYPEARDRQYLLFFHKGAKKSRFDLEKYNQLKDAIAQ
AEMDLKRLRD
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Description
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Functional site
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|
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1)
|
chain |
G |
| residue |
264 |
| type |
|
| sequence |
E
|
| description |
binding site for residue CA G 401
|
| source |
: AC1
|
|
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2)
|
chain |
G |
| residue |
234-255 |
| type |
TRANSMEM |
| sequence |
LVLWGGLAYMATQFGILARLTW
|
| description |
Helical => ECO:0000269|PubMed:31080062, ECO:0000269|PubMed:32494073, ECO:0000269|PubMed:32762847, ECO:0000269|PubMed:32862359, ECO:0007744|PDB:6K7X, ECO:0007744|PDB:6K7Y, ECO:0007744|PDB:6O58, ECO:0007744|PDB:6O5B, ECO:0007744|PDB:6WDN, ECO:0007744|PDB:6WDO, ECO:0007744|PDB:6XJV, ECO:0007744|PDB:6XJX
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| source |
Swiss-Prot : SWS_FT_FI2
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3)
|
chain |
G |
| residue |
263-284 |
| type |
TRANSMEM |
| sequence |
MEPVTYFITYGSAMAMYAYFVM
|
| description |
Helical => ECO:0000269|PubMed:31080062, ECO:0000269|PubMed:32494073, ECO:0000269|PubMed:32762847, ECO:0000269|PubMed:32862359, ECO:0007744|PDB:6K7X, ECO:0007744|PDB:6K7Y, ECO:0007744|PDB:6O58, ECO:0007744|PDB:6O5B, ECO:0007744|PDB:6WDN, ECO:0007744|PDB:6WDO, ECO:0007744|PDB:6XJV, ECO:0007744|PDB:6XJX
|
| source |
Swiss-Prot : SWS_FT_FI2
|
|
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4)
|
chain |
G |
| residue |
256-262 |
| type |
TOPO_DOM |
| sequence |
WEYSWDI
|
| description |
Mitochondrial intermembrane => ECO:0000305|PubMed:27099988, ECO:0000305|PubMed:27642048, ECO:0000305|PubMed:31080062, ECO:0000305|PubMed:32762847
|
| source |
Swiss-Prot : SWS_FT_FI3
|
|
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5)
|
chain |
G |
| residue |
264 |
| type |
BINDING |
| sequence |
E
|
| description |
BINDING => ECO:0000269|PubMed:31080062, ECO:0000269|PubMed:32494073, ECO:0000269|PubMed:32862359, ECO:0007744|PDB:6K7X, ECO:0007744|PDB:6K7Y, ECO:0007744|PDB:6O58, ECO:0007744|PDB:6O5B, ECO:0007744|PDB:6WDO
|
| source |
Swiss-Prot : SWS_FT_FI5
|
|
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6)
|
chain |
G |
| residue |
92 |
| type |
MOD_RES |
| sequence |
S
|
| description |
Phosphoserine; by CaMK2 => ECO:0000305|PubMed:23051746
|
| source |
Swiss-Prot : SWS_FT_FI6
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|
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7)
|
chain |
G |
| residue |
97 |
| type |
MOD_RES |
| sequence |
C
|
| description |
S-glutathionyl cysteine => ECO:0000269|PubMed:28262504
|
| source |
Swiss-Prot : SWS_FT_FI7
|
|
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8)
|
chain |
G |
| residue |
332 |
| type |
MOD_RES |
| sequence |
K
|
| description |
N6-acetyllysine => ECO:0000250|UniProtKB:Q3UMR5
|
| source |
Swiss-Prot : SWS_FT_FI8
|
|
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