eF-site ID 6o5b-ABCDEFGHIJKL PDB Code 6o5b Chain A, B, C, D, E, F, G, H, I, J, K, L click to enlarge Title Monomer of a cation channel Classification TRANSPORT PROTEIN Compound Calcium uniporter protein, mitochondrial Source (EMRE_HUMAN) Sequence A:  DVTVVYQNGLPVISVRLPSRRERCQFTLKPISDSVGVFLR QLQEEDRGIDRVAIYSPDGVRVAASTGIDLLLLDDFKLVI NDLTYHVRPPKRDLLSHENAATLNDVKTLVQQLYTTLCIE QHQLNKERELIERLEDLKEQLAPLEKVRIEISRKAEKRTT LVLWGGLAYMATQFGILARLTWWEYSWDIMEPVTYFITYG SAMAMYAYFVMTRQEYVYPEARDRQYLLFFHKGAKKSRFD LEKYNQLKDAIAQAEMDLKRLRDPLQVHLPLRQ B:  VIVTRSGAILPKPVKMSFGLLRVFSIVIPFLYVGTLISKN FAALLEEHD C:  DVTVVYQNGLPVISVRLPSRRERCQFTLKPISDSVGVFLR QLQEEDRGIDRVAIYSPDGVRVAASTGIDLLLLDDFKLVI NDLTYHVRPPKRDLLSHENAATLNDVKTLVQQLYTTLCIE QHQLNKERELIERLEDLKEQLAPLEKVRIEISRKAEKRTT LVLWGGLAYMATQFGILARLTWWEYSWDIMEPVTYFITYG SAMAMYAYFVMTRQEYVYPEARDRQYLLFFHKGAKKSRFD LEKYNQLKDAIAQAEMDLKRLRDPLQVH D:  VIVTRSGAILPKPVKMSFGLLRVFSIVIPFLYVGTLISKN FAALLEEHD E:  DVTVVYQNGLPVISVRLPSRRERCQFTLKPISDSVGVFLR QLQEEDRGIDRVAIYSPDGVRVAASTGIDLLLLDDFKLVI NDLTYHVRPPKRDLLSHENAATLNDVKTLVQQLYTTLCIE QHQLNKERELIERLEDLKEQLAPLEKVRIEISRKAEKRTT LVLWGGLAYMATQFGILARLTWWEYSWDIMEPVTYFITYG SAMAMYAYFVMTRQEYVYPEARDRQYLLFFHKGAKKSRFD LEKYNQLKDAIAQAEMDLKRLRDPLQVHLP F:  VIVTRSGAILPKPVKMSFGLLRVFSIVIPFLYVGTLISKN FAALLEEHD G:  VTVVYQNGLPVISVRLPSRRERCQFTLKPISDSVGVFLRQ LQEEDRGIDRVAIYSPDGVRVAASTGIDLLLLDDFKLVIN DLTYHVRPPKNDVKTLVQQLYTTLCIEQHQLNKERELIER LEDLKEQLAPLEKVRIEISRKAEKRTTLVLWGGLAYMATQ FGILARLTWWEYSWDIMEPVTYFITYGSAMAMYAYFVMTR QEYVYPEARDRQYLLFFHKGAKKSRFDLEKYNQLKDAIAQ AEMDLKRLRD H:  VIVTRSGAILPKPVKMSFGLLRVFSIVIPFLYVGTLISKN FAALLEEH I:  DVTVVYQNGLPVISVRLPSRRERCQFTLKPISDSVGVFLR QLQEEDRGIDRVAIYSPDGVRVAASTGIDLLLLDDFKLVI NDLTYHVRPPK J:  DVTVVYQNGLPVISVRLPSRRERCQFTLKPISDSVGVFLR QLQEEDRGIDRVAIYSPDGVRVAASTGIDLLLLDDFKLVI NDLTYHVRPPK K:  DVTVVYQNGLPVISVRLPSRRERCQFTLKPISDSVGVFLR QLQEEDRGIDRVAIYSPDGVRVAASTGIDLLLLDDFKLVI NDLTYHVRPPK L:  DVTVVYQNGLPVISVRLPSRRERCQFTLKPISDSVGVFLR QLQEEDRGIDRVAIYSPDGVRVAASTGIDLLLLDDFKLVI NDLTYHVRPPK Description Functional site 1) chain A residue 264 type sequence E description binding site for residue CA G 401 source : AC1 2) chain C residue 264 type sequence E description binding site for residue CA G 401 source : AC1 3) chain E residue 264 type sequence E description binding site for residue CA G 401 source : AC1 4) chain G residue 264 type sequence E description binding site for residue CA G 401 source : AC1 5) chain F residue 53-64 type TOPO_DOM sequence SGAILPKPVKMS description Mitochondrial matrix => ECO:0000305|PubMed:27099988, ECO:0000305|PubMed:27642048 source Swiss-Prot : SWS_FT_FI1 6) chain D residue 53-64 type TOPO_DOM sequence SGAILPKPVKMS description Mitochondrial matrix => ECO:0000305|PubMed:27099988, ECO:0000305|PubMed:27642048 source Swiss-Prot : SWS_FT_FI1 7) chain B residue 53-64 type TOPO_DOM sequence SGAILPKPVKMS description Mitochondrial matrix => ECO:0000305|PubMed:27099988, ECO:0000305|PubMed:27642048 source Swiss-Prot : SWS_FT_FI1 8) chain H residue 53-64 type TOPO_DOM sequence SGAILPKPVKMS description Mitochondrial matrix => ECO:0000305|PubMed:27099988, ECO:0000305|PubMed:27642048 source Swiss-Prot : SWS_FT_FI1 9) chain F residue 65-84 type TRANSMEM sequence FGLLRVFSIVIPFLYVGTLI description Helical => ECO:0000255 source Swiss-Prot : SWS_FT_FI2 10) chain A residue 266-283 type TRANSMEM sequence VTYFITYGSAMAMYAYFV description Helical => ECO:0000255 source Swiss-Prot : SWS_FT_FI2 11) chain G residue 234-256 type TRANSMEM sequence LVLWGGLAYMATQFGILARLTWW description Helical => ECO:0000255 source Swiss-Prot : SWS_FT_FI2 12) chain G residue 266-283 type TRANSMEM sequence VTYFITYGSAMAMYAYFV description Helical => ECO:0000255 source Swiss-Prot : SWS_FT_FI2 13) chain D residue 65-84 type TRANSMEM sequence FGLLRVFSIVIPFLYVGTLI description Helical => ECO:0000255 source Swiss-Prot : SWS_FT_FI2 14) chain B residue 65-84 type TRANSMEM sequence FGLLRVFSIVIPFLYVGTLI description Helical => ECO:0000255 source Swiss-Prot : SWS_FT_FI2 15) chain H residue 65-84 type TRANSMEM sequence FGLLRVFSIVIPFLYVGTLI description Helical => ECO:0000255 source Swiss-Prot : SWS_FT_FI2 16) chain E residue 234-256 type TRANSMEM sequence LVLWGGLAYMATQFGILARLTWW description Helical => ECO:0000255 source Swiss-Prot : SWS_FT_FI2 17) chain E residue 266-283 type TRANSMEM sequence VTYFITYGSAMAMYAYFV description Helical => ECO:0000255 source Swiss-Prot : SWS_FT_FI2 18) chain C residue 234-256 type TRANSMEM sequence LVLWGGLAYMATQFGILARLTWW description Helical => ECO:0000255 source Swiss-Prot : SWS_FT_FI2 19) chain C residue 266-283 type TRANSMEM sequence VTYFITYGSAMAMYAYFV description Helical => ECO:0000255 source Swiss-Prot : SWS_FT_FI2 20) chain A residue 234-256 type TRANSMEM sequence LVLWGGLAYMATQFGILARLTWW description Helical => ECO:0000255 source Swiss-Prot : SWS_FT_FI2 21) chain A residue 257-265 type TOPO_DOM sequence EYSWDIMEP description Mitochondrial intermembrane => ECO:0000305|PubMed:27099988, ECO:0000305|PubMed:27642048 source Swiss-Prot : SWS_FT_FI3 22) chain G residue 257-265 type TOPO_DOM sequence EYSWDIMEP description Mitochondrial intermembrane => ECO:0000305|PubMed:27099988, ECO:0000305|PubMed:27642048 source Swiss-Prot : SWS_FT_FI3 23) chain A residue 92 type MOD_RES sequence S description Phosphoserine; by CaMK2 => ECO:0000305|PubMed:23051746 source Swiss-Prot : SWS_FT_FI5 24) chain L residue 92 type MOD_RES sequence S description Phosphoserine; by CaMK2 => ECO:0000305|PubMed:23051746 source Swiss-Prot : SWS_FT_FI5 25) chain I residue 92 type MOD_RES sequence S description Phosphoserine; by CaMK2 => ECO:0000305|PubMed:23051746 source Swiss-Prot : SWS_FT_FI5 26) chain G residue 92 type MOD_RES sequence S description Phosphoserine; by CaMK2 => ECO:0000305|PubMed:23051746 source Swiss-Prot : SWS_FT_FI5 27) chain J residue 92 type MOD_RES sequence S description Phosphoserine; by CaMK2 => ECO:0000305|PubMed:23051746 source Swiss-Prot : SWS_FT_FI5 28) chain K residue 92 type MOD_RES sequence S description Phosphoserine; by CaMK2 => ECO:0000305|PubMed:23051746 source Swiss-Prot : SWS_FT_FI5 29) chain E residue 92 type MOD_RES sequence S description Phosphoserine; by CaMK2 => ECO:0000305|PubMed:23051746 source Swiss-Prot : SWS_FT_FI5 30) chain C residue 92 type MOD_RES sequence S description Phosphoserine; by CaMK2 => ECO:0000305|PubMed:23051746 source Swiss-Prot : SWS_FT_FI5 31) chain E residue 332 type MOD_RES sequence K description N6-acetyllysine => ECO:0000250|UniProtKB:Q3UMR5 source Swiss-Prot : SWS_FT_FI6 32) chain C residue 332 type MOD_RES sequence K description N6-acetyllysine => ECO:0000250|UniProtKB:Q3UMR5 source Swiss-Prot : SWS_FT_FI6 33) chain A residue 332 type MOD_RES sequence K description N6-acetyllysine => ECO:0000250|UniProtKB:Q3UMR5 source Swiss-Prot : SWS_FT_FI6 34) chain G residue 332 type MOD_RES sequence K description N6-acetyllysine => ECO:0000250|UniProtKB:Q3UMR5 source Swiss-Prot : SWS_FT_FI6

Display surface Download Links