eF-site ID 6o0o-A PDB Code 6o0o Chain A click to enlarge Title crystal structure of BCL-2 G101V mutation with S55746 Classification APOPTOSIS Compound Apoptosis regulator Bcl-2,Bcl-2-like protein 1,Apoptosis regulator Bcl-2 Source (BCL2_HUMAN) Sequence A:  YDNREIVMKYIHYKLSQRGYEWDAEVVHLTLRQAVDDFSR RYRRDFAEMSSQLHLTPFTARGRFATVVEELFRDGVNWGR IVAFFEFGGVMCVESVNREMSPLVDNIALWMTEYLNRHLH TWIQDNGGWDAFVELYG Description Functional site 1) chain A residue 63 type sequence F description binding site for residue F3Q A 201 source : AC1 2) chain A residue 67 type sequence Y description binding site for residue F3Q A 201 source : AC1 3) chain A residue 70 type sequence D description binding site for residue F3Q A 201 source : AC1 4) chain A residue 71 type sequence F description binding site for residue F3Q A 201 source : AC1 5) chain A residue 74 type sequence M description binding site for residue F3Q A 201 source : AC1 6) chain A residue 88 type sequence R description binding site for residue F3Q A 201 source : AC1 7) chain A residue 92 type sequence V description binding site for residue F3Q A 201 source : AC1 8) chain A residue 95 type sequence E description binding site for residue F3Q A 201 source : AC1 9) chain A residue 96 type sequence L description binding site for residue F3Q A 201 source : AC1 10) chain A residue 104 type sequence G description binding site for residue F3Q A 201 source : AC1 11) chain A residue 105 type sequence R description binding site for residue F3Q A 201 source : AC1 12) chain A residue 108 type sequence A description binding site for residue F3Q A 201 source : AC1 13) chain A residue 112 type sequence F description binding site for residue F3Q A 201 source : AC1 14) chain A residue 96-114 type prosite sequence LFRDGVNWGRIVAFFEFGG description BH1 Apoptosis regulator, Bcl-2 family BH1 motif signature. LFrDGv.NWGRIVAFFeFGG source prosite : PS01080 15) chain A residue 147-158 type prosite sequence WIQDNGGWDAFV description BH2 Apoptosis regulator, Bcl-2 family BH2 motif signature. WIqdnGGWDaFV source prosite : PS01258 16) chain A residue 10-30 type prosite sequence DNREIVMKYIHYKLSQRGYEW description BH4_1 Apoptosis regulator, Bcl-2 family BH4 motif signature. DNREIVmKYIHYKLSQRGYeW source prosite : PS01260

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