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eF-site ID
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6nm9-D |
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PDB Code
|
6nm9 |
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Chain
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D |
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click to enlarge
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Title
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CryoEM structure of the LbCas12a-crRNA-AcrVA4 dimer |
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Classification
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UNKNOWN FUNCTION/RNA |
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Compound
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AcrVA4 |
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Source
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(6NM9) |
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Sequence
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D: |
MSKLEKFTNCYSLSKTLRFKAIPVGKTQENIDNKRLLVED
EKRAEDYKGVKKLLDRYYLSFINDVLHSIKLKNLNNYISL
FRKKTRTEKENKELENLEINLRKEIAKAFKGNEGYKSLFK
KDIIETILPEFLDDKDEIALVNSFNGFTTAFTGFFDNREN
MFSEEAKSTSIAFRCINENLTRYISNMDIFEKVDAIFDKH
EVQEIKEKILNSDYDVEDFFEGEFFNFVLTQEGIDVYNAI
IGGFVTESGEKIKGLNEYINLYNQKTKQKLPKFKPLYKQV
EGYTSDEEVLEVFRNTLNKNSEIFSSIKKLEKLFKNFDEY
SSAGIFVKNGPAISTISKDIFGEWNVIRDKWNAEYDDIHL
KKKAVVTEKYEDDRRKSFKKIGSFSLEQLQEYADADLSVV
EKLKEIIIQKVDEIYKVYGSSEKLFDADFVLEKSLKKNDA
VVAIMKDLLDSVKSFENYIKAFFGEKETNRDESFYGDFVL
AYDILLKVDHIYDAIRNYVTQKPYSKDKFKLYFQNPQFMG
GWDKDKETDYRATILRYGSKYYLAIMDKKYAKCLQKIDKD
DVNGNYEKINYKLLPGPNKMLPKVFFSKKWMAYYNSEDIQ
KIYKNGTFKKGDMFNLNDCHKLIDFFKDSISRYPKWSNAY
DFNFSETEKYKDIAGFYREVEEQGYKVSFESASKKEVDKL
VEEGKLYMFQIYNKDFSDKSHGTPNLHTMYFKLLFDENNH
GQIRLSGGAELFMRRASLKKEELVVHPANSPIANKNPDNP
KKTTTLSYDVYKDKRFSEDQYELHIPIAINKCPKNIFKIN
TEVRVLLKHDDNPYVIGIDRGERNLLYIVVVDGKGNIVEQ
YSLNEIINNFNGIRIKTDYHSLLDKKEKERFEARQNWTSI
ENIKELKAGYISQVVHKICELVEKYDAVIALEDLNSGFKN
SRVKVEKQVYQKFEKMLIDKLNYMVDKKSNPCATGGALKG
YQITNKFESFKSMSTQNGFIFYIPAWLTSKIDPSTGFVNL
LKTKYTSIADSKKFISSFDRIMYVPEEDLFEFALDYKNFS
RTDADYIKKWKLYSYGNRIRIFFDWEEVCLTSAYKELFNK
YGINYQQDIRALLCEQSDKAFYSSFMALMSLMLQMRNSIT
GRTDVDFLISPVKNSDGIFYDSRNYEAQENAILPKNADAN
GAYNIARKVLWAIGQFKKAEDEKLDKVKIAISNKEWLEYA
QTSVK
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Description
|
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Functional site
|
|
|
1)
|
chain |
D |
| residue |
716 |
| type |
|
| sequence |
T
|
| description |
binding site for residue MG D 1301
|
| source |
: AC4
|
|
|
2)
|
chain |
D |
| residue |
718 |
| type |
|
| sequence |
N
|
| description |
binding site for residue MG D 1301
|
| source |
: AC4
|
|
|
|