eF-site ID 6nje-A PDB Code 6nje Chain A click to enlarge Title Crystal structure of the motor domain of human kinesin family member 22 Classification TRANSPORT PROTEIN Compound Kinesin-like protein KIF22 Source (KIF22_HUMAN) Sequence A:  LYFQGPPARVRVAVRLRPFVCSLEIANWRNHQETLKYQFD AFYGERSTQQDIYAGSVQPILRHLLEGQNASVLAYGPTGA GKTHTMLGSPEQPGVIPRALMDLLQLTREEGAEGRPWALS VTMSYLEIYQEKVLDLLDPASGDLVIREDCRGNILIPGLS QKPISSFADFERHFLPASRRSSRSHAVLLVKVDQRERLAP FRQREGKLYLIDLAGSEDNRRTGAINTSLFVLGKVVDALN QGLPRVPYRDSKLTRLLQDSLGGSAHSILIANIAPERRFY LDTVSALNFAARSKEVI Description Functional site 1) chain A residue 134 type sequence T description binding site for residue MG A 801 source : AC1 2) chain A residue 49 type sequence R description binding site for residue ADP A 802 source : AC2 3) chain A residue 51 type sequence R description binding site for residue ADP A 802 source : AC2 4) chain A residue 52 type sequence P description binding site for residue ADP A 802 source : AC2 5) chain A residue 128 type sequence P description binding site for residue ADP A 802 source : AC2 6) chain A residue 129 type sequence T description binding site for residue ADP A 802 source : AC2 7) chain A residue 130 type sequence G description binding site for residue ADP A 802 source : AC2 8) chain A residue 131 type sequence A description binding site for residue ADP A 802 source : AC2 9) chain A residue 132 type sequence G description binding site for residue ADP A 802 source : AC2 10) chain A residue 133 type sequence K description binding site for residue ADP A 802 source : AC2 11) chain A residue 134 type sequence T description binding site for residue ADP A 802 source : AC2 12) chain A residue 135 type sequence H description binding site for residue ADP A 802 source : AC2 13) chain A residue 45 type sequence R description binding site for residue CL A 803 source : AC3 14) chain A residue 97 type sequence R description binding site for residue CL A 803 source : AC3 15) chain A residue 120 type sequence N description binding site for residue CL A 804 source : AC4 16) chain A residue 336 type sequence S description binding site for residue CL A 804 source : AC4 17) chain A residue 337 type sequence A description binding site for residue CL A 804 source : AC4 18) chain A residue 99 type sequence T description binding site for residue CL A 805 source : AC5 19) chain A residue 100 type sequence Q description binding site for residue CL A 805 source : AC5 20) chain A residue 143 type sequence Q description binding site for residue CL A 805 source : AC5 21) chain A residue 35 type sequence L description binding site for residue NA A 806 source : AC6 22) chain A residue 36 type sequence Y description binding site for residue NA A 806 source : AC6 23) chain A residue 37 type sequence F description binding site for residue NA A 806 source : AC6 24) chain A residue 38 type sequence Q description binding site for residue NA A 806 source : AC6 25) chain A residue 39 type sequence G description binding site for residue NA A 806 source : AC6 26) chain A residue 127 type BINDING sequence G description BINDING => ECO:0000255|PROSITE-ProRule:PRU00283 source Swiss-Prot : SWS_FT_FI1 27) chain A residue 268-279 type prosite sequence GKLYLIDLAGSE description KINESIN_MOTOR_1 Kinesin motor domain signature. GKLyLIDLAGSE source prosite : PS00411

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