eF-site ID 6nig-ABCD PDB Code 6nig Chain A, B, C, D click to enlarge Title Crystal structure of the human TLR2-Diprovocim complex Classification IMMUNE SYSTEM/AGONIST Compound Toll-like receptor 2,Variable lymphocyte receptor B Source (Q2YE02_EPTST) Sequence A:  SLSCDRNGICKGSSGSLNSIPSGLTEAVKSLDLSNNRITY ISNSDLQRCVNLQALVLTSNGINTIEEDSFSSLGSLEHLD LSYNYLSNLSSSWFKPLSSLTFLNLLGNPYKTLGETSLFS HLTKLQILRVGNMDTFTKIQRKDFAGLTFLEELEIDASDL QSYEPKSLKSIQNVSHLILHMKQHILLLEIFVDVTSSVEC LELRDTDLDTFHFSELSTNSLIKKFTFRNVKITDESLFQV MKLLNQISGLLELEFDDCTLNGVGNFRASDNDRVIDPGKV ETLTIRRLHIPRFYLFYDLSTLYSLTERVKRITVENSKVF LVPCLLSQHLKSLEYLDLSENLMVEEYLKNSACEDAWPSL QTLILRQNHLASLEKTGETLLTLKNLTNIDISKNSFHSMP ETCQWPEKMKYLNLSSTRIHSVTGCIPKTLEILDVSNNNL NLFSLNLPQLKELYISRNKLMTLPDASLLPMLLVLKISRN QLKSVPDGIFDRLTSLQKIWLHTNPWDCSCPRIDYLSRWL NKNSQKEQGSAKCSGSGKPVRSIICP B:  SLSCDRNGICKGSSGSLNSIPSGLTEAVKSLDLSNNRITY ISNSDLQRCVNLQALVLTSNGINTIEEDSFSSLGSLEHLD LSYNYLSNLSSSWFKPLSSLTFLNLLGNPYKTLGETSLFS HLTKLQILRVGNMDTFTKIQRKDFAGLTFLEELEIDASDL QSYEPKSLKSIQNVSHLILHMKQHILLLEIFVDVTSSVEC LELRDTDLDTFHFSELSTGETNSLIKKFTFRNVKITDESL FQVMKLLNQISGLLELEFDDCTLNGVGNFRASDIDPGKVE TLTIRRLHIPRFYLFYDLSTLYSLTERVKRITVENSKVFL VPCLLSQHLKSLEYLDLSENLMVEEYLKNSACEDAWPSLQ TLILRQNHLASLEKTGETLLTLKNLTNIDISKNSFHSMPE TCQWPEKMKYLNLSSTRIHSVTGCIPKTLEILDVSNNNLN LFSLNLPQLKELYISRNKLMTLPDASLLPMLLVLKISRNQ LKSVPDGIFDRLTSLQKIWLHTNPWDCSCPRIDYLSRWLN KNSQKEQGSAKCSGSGKPVRSIICP C:  SLSCDRNGICKGSSGSLNSIPSGLTEAVKSLDLSNNRITY ISNSDLQRCVNLQALVLTSNGINTIEEDSFSSLGSLEHLD LSYNYLSNLSSSWFKPLSSLTFLNLLGNPYKTLGETSLFS HLTKLQILRVGNMDTFTKIQRKDFAGLTFLEELEIDASDL QSYEPKSLKSIQNVSHLILHMKQHILLLEIFVDVTSSVEC LELRDTDLDTFHFSELSTGETNSLIKKFTFRNVKITDESL FQVMKLLNQISGLLELEFDDCTLNGVGNFRASDNDRVIDP GKVETLTIRRLHIPRFYLFYDLSTLYSLTERVKRITVENS KVFLVPCLLSQHLKSLEYLDLSENLMVEEYLKNSACEDAW PSLQTLILRQNHLASLEKTGETLLTLKNLTNIDISKNSFH SMPETCQWPEKMKYLNLSSTRIHSVTGCIPKTLEILDVSN NNLNLFSLNLPQLKELYISRNKLMTLPDASLLPMLLVLKI SRNQLKSVPDGIFDRLTSLQKIWLHTNPWDCSCPRIDYLS RWLNKNSQKEQGSAKCSGSGKPVRSIICP D:  SLSCDRNGICKGSSGSLNSIPSGLTEAVKSLDLSNNRITY ISNSDLQRCVNLQALVLTSNGINTIEEDSFSSLGSLEHLD LSYNYLSNLSSSWFKPLSSLTFLNLLGNPYKTLGETSLFS HLTKLQILRVGNMDTFTKIQRKDFAGLTFLEELEIDASDL QSYEPKSLKSIQNVSHLILHMKQHILLLEIFVDVTSSVEC LELRDTDLDTFHFSELSTGETNSLIKKFTFRNVKITDESL FQVMKLLNQISGLLELEFDDCTLNGVGNFRASDVIDPGKV ETLTIRRLHIPRFYLFYDLSTLYSLTERVKRITVENSKVF LVPCLLSQHLKSLEYLDLSENLMVEEYLKNSACEDAWPSL QTLILRQNHLASLEKTGETLLTLKNLTNIDISKNSFHSMP ETCQWPEKMKYLNLSSTRIHSVTGCIPKTLEILDVSNNNL NLFSLNLPQLKELYISRNKLMTLPDASLLPMLLVLKISRN QLKSVPDGIFDRLTSLQKIWLHTNPWDCSCPRIDYLSRWL NKNSQKEQGSAKCSGSGKPVRSIICP Description Functional site 1) chain A residue 349 type SITE sequence F description Interaction with bacterial lipopeptide source Swiss-Prot : SWS_FT_FI1 2) chain B residue 349 type SITE sequence F description Interaction with bacterial lipopeptide source Swiss-Prot : SWS_FT_FI1 3) chain C residue 349 type SITE sequence F description Interaction with bacterial lipopeptide source Swiss-Prot : SWS_FT_FI1 4) chain D residue 349 type SITE sequence F description Interaction with bacterial lipopeptide source Swiss-Prot : SWS_FT_FI1 5) chain A residue 114 type CARBOHYD sequence N description N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:15173186, ECO:0000269|PubMed:17889651 source Swiss-Prot : SWS_FT_FI2 6) chain D residue 114 type CARBOHYD sequence N description N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:15173186, ECO:0000269|PubMed:17889651 source Swiss-Prot : SWS_FT_FI2 7) chain D residue 199 type CARBOHYD sequence N description N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:15173186, ECO:0000269|PubMed:17889651 source Swiss-Prot : SWS_FT_FI2 8) chain D residue 442 type CARBOHYD sequence N description N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:15173186, ECO:0000269|PubMed:17889651 source Swiss-Prot : SWS_FT_FI2 9) chain A residue 199 type CARBOHYD sequence N description N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:15173186, ECO:0000269|PubMed:17889651 source Swiss-Prot : SWS_FT_FI2 10) chain A residue 442 type CARBOHYD sequence N description N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:15173186, ECO:0000269|PubMed:17889651 source Swiss-Prot : SWS_FT_FI2 11) chain B residue 114 type CARBOHYD sequence N description N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:15173186, ECO:0000269|PubMed:17889651 source Swiss-Prot : SWS_FT_FI2 12) chain B residue 199 type CARBOHYD sequence N description N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:15173186, ECO:0000269|PubMed:17889651 source Swiss-Prot : SWS_FT_FI2 13) chain B residue 442 type CARBOHYD sequence N description N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:15173186, ECO:0000269|PubMed:17889651 source Swiss-Prot : SWS_FT_FI2 14) chain C residue 114 type CARBOHYD sequence N description N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:15173186, ECO:0000269|PubMed:17889651 source Swiss-Prot : SWS_FT_FI2 15) chain C residue 199 type CARBOHYD sequence N description N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:15173186, ECO:0000269|PubMed:17889651 source Swiss-Prot : SWS_FT_FI2 16) chain C residue 442 type CARBOHYD sequence N description N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:15173186, ECO:0000269|PubMed:17889651 source Swiss-Prot : SWS_FT_FI2 17) chain A residue 414 type CARBOHYD sequence N description N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:17889651 source Swiss-Prot : SWS_FT_FI3 18) chain B residue 414 type CARBOHYD sequence N description N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:17889651 source Swiss-Prot : SWS_FT_FI3 19) chain C residue 414 type CARBOHYD sequence N description N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:17889651 source Swiss-Prot : SWS_FT_FI3 20) chain D residue 414 type CARBOHYD sequence N description N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:17889651 source Swiss-Prot : SWS_FT_FI3

Display surface Download Links