|
|
eF-site ID
|
6nig-A |
|
PDB Code
|
6nig |
|
Chain
|
A |
|
click to enlarge
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|
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Title
|
Crystal structure of the human TLR2-Diprovocim complex |
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Classification
|
IMMUNE SYSTEM/AGONIST |
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Compound
|
Toll-like receptor 2,Variable lymphocyte receptor B |
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Source
|
(Q2YE02_EPTST) |
|
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Sequence
|
A: |
SLSCDRNGICKGSSGSLNSIPSGLTEAVKSLDLSNNRITY
ISNSDLQRCVNLQALVLTSNGINTIEEDSFSSLGSLEHLD
LSYNYLSNLSSSWFKPLSSLTFLNLLGNPYKTLGETSLFS
HLTKLQILRVGNMDTFTKIQRKDFAGLTFLEELEIDASDL
QSYEPKSLKSIQNVSHLILHMKQHILLLEIFVDVTSSVEC
LELRDTDLDTFHFSELSTNSLIKKFTFRNVKITDESLFQV
MKLLNQISGLLELEFDDCTLNGVGNFRASDNDRVIDPGKV
ETLTIRRLHIPRFYLFYDLSTLYSLTERVKRITVENSKVF
LVPCLLSQHLKSLEYLDLSENLMVEEYLKNSACEDAWPSL
QTLILRQNHLASLEKTGETLLTLKNLTNIDISKNSFHSMP
ETCQWPEKMKYLNLSSTRIHSVTGCIPKTLEILDVSNNNL
NLFSLNLPQLKELYISRNKLMTLPDASLLPMLLVLKISRN
QLKSVPDGIFDRLTSLQKIWLHTNPWDCSCPRIDYLSRWL
NKNSQKEQGSAKCSGSGKPVRSIICP
|
|
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Description
|
|
Functional site
|
|
|
1)
|
chain |
A |
| residue |
414 |
| type |
CARBOHYD |
| sequence |
N
|
| description |
N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:17889651
|
| source |
Swiss-Prot : SWS_FT_FI3
|
|
|
2)
|
chain |
A |
| residue |
349 |
| type |
SITE |
| sequence |
F
|
| description |
Interaction with bacterial lipopeptide
|
| source |
Swiss-Prot : SWS_FT_FI1
|
|
|
3)
|
chain |
A |
| residue |
114 |
| type |
CARBOHYD |
| sequence |
N
|
| description |
N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:15173186, ECO:0000269|PubMed:17889651
|
| source |
Swiss-Prot : SWS_FT_FI2
|
|
|
4)
|
chain |
A |
| residue |
199 |
| type |
CARBOHYD |
| sequence |
N
|
| description |
N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:15173186, ECO:0000269|PubMed:17889651
|
| source |
Swiss-Prot : SWS_FT_FI2
|
|
|
5)
|
chain |
A |
| residue |
442 |
| type |
CARBOHYD |
| sequence |
N
|
| description |
N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:15173186, ECO:0000269|PubMed:17889651
|
| source |
Swiss-Prot : SWS_FT_FI2
|
|
|
|